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Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491034
EISBN: 978-3-318-06409-4
... concentrations. Hypercalcemia may be distinguished in parathyroid-hypercalcemia and nonparathyroid hypercalcemia. The most common disorders include primary hyperparathyroidism (PHPT), malignancy, granulomatous diseases, and medications. PHPT is a disease characterized by excessive secretion of PTH. PHPT is most...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491035
EISBN: 978-3-318-06409-4
.... Asymptomatic primary hyperparathyroidism (PHPT) is viewed as a milder presentation of classical PHPT [ 1 ]. Despite meeting biochemical criteria for the diagnosis, asymptomatic patients often do not meet other criteria for surgery, and many patients without symptoms are observed without surgery. Over time...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
10.1159/000486076
EISBN: 978-3-318-06339-4
... Abstract Primary hyperparathyroidism (PHPT) is a common disorder of mineral metabolism characterized by hypercalcemia and incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands. PHPT is most often asymptomatic, but it does increase the risk...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491037
EISBN: 978-3-318-06409-4
... Abstract Individuals with a familial predisposition to the development of parathyroid tumors constitute a small minority of all patients with primary hyperparathyroidism (PHPT). These familial syndromes exhibit Mendelian inheritance patterns and the main causative genes in most families have...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 49
Published: 26 April 2018
10.1159/000486003
EISBN: 978-3-318-06335-6
.... Fig. 1 Spectrum of biochemical presentations of parathyroid disorders. PTH, parathormone; SHPT, secondary hyperparathyroidism; PHPT, primary hyperparathyroidism; HypoPT, hypoparathyroidism; PseudohypoPT, pseudohypoparathyroidism; FHH, familial hypocalciuric hypercalcemia; MEN1, multiple endocrine...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491036
EISBN: 978-3-318-06409-4
... primary hyperparathyroidism (PHPT) associated with persistent normal serum calcium levels, which has been recognized as a distinct entity from hypercalcemic PHPT (HPHPT) by the last international consensus. Normocalcemic PHPT (NPHPT) affects about 6-8% of PHPT patients. Although hypercalcemia is absent...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491038
EISBN: 978-3-318-06409-4
... early parathyroidectomy for young patients to survive. Recent discoveries in the genetic basis and new findings in therapeutic approaches have led to a great interest in these rare diseases. A minority of cases of primary hyperparathyroidism (PHPT) are not sporadic, but rather genetically...
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Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/isbn.978-3-318-06409-4
EISBN: 978-3-318-06409-4
Book Chapter
Series: Endocrine Development
Volume: 28
Published: 11 June 2015
10.1159/000380998
EISBN: 978-3-318-05467-5
... is rare in children and is a much less common problem than hypocalcaemia. In adulthood, the causes are most frequently malignancy and primary hyperparathyroidism (PHPT). In children, however, the aetiologies are diverse and age specific, and many have an underlying genetic basis. Hypercalcaemia...
Book Chapter
Series: Endocrine Development
Volume: 26
Published: 15 September 2014
10.1159/000363165
EISBN: 978-3-318-02721-1
... of RET mutated gene carriers, even before the clinical evidence of the disease. In MEN2A about 50% of patients develop a tumor in the adrenal medulla called pheochromocytoma (Pheo) and less frequently primary hyperparathyroidism (PHPT) (25%) [ 4 ]. Pheo in MEN2A is usually nonmalignant (limited...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491039
EISBN: 978-3-318-06409-4
... Abstract Parathyroid carcinoma (PC) is a rare endocrine malignancy, accounting for <1% of all cases of sporadic primary hyperparathyroidism (PHPT) and up to 15% in the hereditary hyperparathyroidism-jaw tumor syndrome. Genomic alterations identified in PC are mostly represented by CDC73...
Book Chapter
Series: Frontiers in Diabetes
Volume: 22
Published: 10 April 2014
10.1159/000357251
EISBN: 978-3-318-02598-9
... sensitivity ( b ) and first-phase beta cell sensitivity to glucose ( c ) of patients with primary hyperparathyroidism (PHPT-Pre) with normal glucose tolerance (NGT-PHPT-Pre) and impaired glucose tolerance (IGT-PHPT-Pre) before surgery, compared with primary hyperparathyroidism patients after surgery (PHPT...
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Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
10.1159/isbn.978-3-318-06339-4
EISBN: 978-3-318-06339-4
Book
Book Cover Image
Series: Frontiers of Hormone Research
Volume: 49
Published: 26 April 2018
10.1159/isbn.978-3-318-06335-6
EISBN: 978-3-318-06335-6
Book
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Series: Progress in Surgery
Volume: 18
Published: 07 May 1986
10.1159/isbn.978-3-318-04148-4
EISBN: 978-3-318-04148-4
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
EISBN: 978-3-318-06339-4
... in patients with primary hyperparathyroidism (PHPT) and coexistent vitamin D deficiency on serum 25(OH) D, calcium and PTH levels: a meta-analysis and review of literature. Clin Endocrinol (Oxf) 2014;80:797-803. 47. Rolighed L, Vestergaard P, Heickendorff L, et al: BMD improvements after operation...
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Series: Contributions to Nephrology
Volume: 79
Published: 04 July 1990
10.1159/isbn.978-3-318-03343-4
EISBN: 978-3-318-03343-4
Book
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Published: 23 April 2002
10.1159/isbn.978-3-318-00811-1
EISBN: 978-3-318-00811-1
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Published: 04 August 2009
10.1159/isbn.978-3-8055-9150-8
EISBN: 978-3-8055-9150-8
Book
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Series: Frontiers in Diabetes
Volume: 22
Published: 10 April 2014
10.1159/isbn.978-3-318-02598-9
EISBN: 978-3-318-02598-9