... Abstract For the risk of maternal and fetal complications, gestational diabetes mellitus (GDM) requires strict care. When lifestyle intervention (i.e., nutritional medical therapy and physical activity) is not effective in keeping blood glucose at target, a pharmacological treatment is needed...

... Abstract Surgery aimed at hearing rehabilitation risks damaging residual inner ear function, especially cochlear implant surgery. Pharmacological intervention to reduce this risk has shown great promise in animal models. The challenge is to deliver medication to the appropriate part...

... of anti-inflammatory drugs under the perspective of current pharmacological and neurophysiological data. This evaluation included the use of nonsteroidal anti-inflammatory drugs (NSAIDs) as adjunctive treatment to conventional pharmacotherapy as well as the use of natural products exerting anti...

... be attenuated or reduced by both pharmacological and non-pharmacological interventions. Alvarez-Jimenez et al. [ 23 ] undertook a meta-analysis and found that nutritional counselling, cognitive-behavioural therapy and individual or group interventions could reduce weight gain. Curtis et al. [ 24 ] demonstrated...

... allergic reactions, should they occur. The pharmacological management of acute food-induced allergic reactions is dependent on the underlying pathophysiology of the allergic reaction and the severity of clinical symptoms and signs. Mild to moderate symptoms of an immunoglobulin E-mediated acute allergic...

... successful treatment strategy for panic disorder. This chapter also includes treatment recommendations for pregnant or lactating women, children, adolescents, elderly patients, and patients who are non-responsive to standard treatments. Pharmacological treatment of panic disorder emerged in 1959...

... placebo-controlled studies [ 50 , 51 ]. The findings of a meta-analytic review demonstrate that pharmacological and psychological treatments, when delivered singly, have broadly similar efficacy in acute treatment [ 52 ]. However, acute treatment with cognitive therapy (group or individual) is possibly...

... permit. When health and nutrition are not limiting factors, the growth patterns and adult heights achieved by humans are remarkably constrained, as evidenced by the relatively limited variation in adult stature for both males and females. It is against this background that pharmacological intervention...

... Abstract The first section of this chapter details current, marketed pharmacological treatments for Alzheimer’s disease, the extent of efficacy, adverse effects, and the controversies surrounding their use, including when to treat, for how long, expected effects, and long-term adversity...

... inflammatory diseases such as periodontitis. This chapter focuses on the shift in emphasis from the periodontal infection to periodontal inflammation as the target for pharmacological interventions for treatment of periodontal diseases. What Is Unique about Periodontal Diseases? Anatomically, teeth...

... these two organ systems, but also an appreciation of the pharmacological effects of agents targeting one organ and their influence on the other. For instance, treatment of cardiovascular diseases and risk factors may influence, in a beneficial or harmful way, renal function and progression of renal injury...

...- found effect on the treatment of schizophrenia, but the cognitive deficits associated with this disorder have been insufficiently addressed. It is therefore critical to con- tinue the search for novel pharmacological approaches to achieve meaningful gains in this regard. The following molecular targets...

... because of their implication inthe amyloid cascade, randomized controlled trials have yielded largely negative results. Therefore,pharmacological as well as fundamental research that better underpins the complex pathophysiologyof this devastating disease constitutes one of the biggest challenges...