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Book Chapter
Series: Progress in Neurological Surgery
Volume: 35
Published: 18 December 2020
10.1159/000509574
EISBN: 978-3-318-06795-8
... Abstract Trigeminal branch stimulation is a type of peripheral nerve stimulation (PNS) used to treat a variety of craniofacial pain disorders. Common indications include trigeminal neuralgia, trigeminal neuropathic pain, trigeminal deafferentation pain, trigeminal postherpetic neuralgia...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 35
Published: 18 December 2020
10.1159/000509622
EISBN: 978-3-318-06795-8
... Abstract The introduction of peripheral neuromodulation to treat headache and facial pain two decades ago opened up the field to non-neurosurgical practitioners, given the relatively low risk and technical ease of the procedure. These procedures, primarily occipital nerve stimulation (ONS...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 35
Published: 18 December 2020
10.1159/000509653
EISBN: 978-3-318-06795-8
... Abstract Since its original introduction several decades ago, peripheral nerve stimulation (PNS) of the craniofacial region has been traditionally performed using devices intended for spinal cord stimulation applications with inevitably high rate of technical challenges and procedural...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 35
Published: 18 December 2020
10.1159/000509665
EISBN: 978-3-318-06795-8
... for peripheral nerve stimulation, available until the last decade, utilised frequencies in the range 1–100 Hz. With the commercial introduction of 10-kHz spinal cord stimulation, there has been renewed interest in peripheral applications of kHz frequency neuromodulation. High-frequency biphasic stimulation...
Book
Book Chapter
Series: Frontiers in Diabetes
Volume: 26
Published: 11 December 2017
10.1159/000480046
EISBN: 978-3-318-06145-1
... Abstract Peripheral arterial disease is a major risk factor for amputation in patients with diabetes. Its presentation is different from that of the occlusive arterial disease in patients without diabetes. In diabetes, peripheral arterial disease develops at a younger age and women and men...
Book Chapter
Series: Endocrine Development
Volume: 32
Published: 21 August 2017
10.1159/000475734
EISBN: 978-3-318-05974-8
... intake and energy homeostasis and their effects on peripheral tissues versus central nervous system actions. Research on the field of childhood obesity is critical as glucose intolerance and hypertension often develop already during childhood and are strongly associated in adulthood...
Book Chapter
Series: Current Problems in Dermatology
Volume: 50
Published: 01 September 2016
10.1159/000446012
EISBN: 978-3-318-05889-5
... with and activate pruriceptors on the sensory nerve fibers. These peripheral fibers convey signals from the skin to the dorsal root and trigeminal ganglia and on to the spinal cord and brain where central processing of the itch sensation occurs. A discussion of the nature and sources of itch stimuli and receptors...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 38
Published: 04 April 2016
10.1159/000442568
EISBN: 978-3-318-05606-8
... of the front during World War I (WWI) contributed to a dramatic increase in knowledge about peripheral nerve injuries. Silas Weir Mitchell's original experience with respect to these injuries, and particularly causalgia, during the American Civil War was further expanded in Europe during WWI. Following...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438895
EISBN: 978-3-318-02789-1
... Abstract There are many etiologies of peripheral precocious puberty (PPP) with diverse manifestations resulting from exposure to androgens, estrogens, or both. The clinical presentation depends on the underlying process and may be acute or gradual. The primary goals of therapy are to halt...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/000434651
EISBN: 978-3-318-02809-6
... Abstract Peripheral nerve stimulation (PNS) has been in use for over 50 years to treat patients suffering from chronic pain who have failed conservative treatments. Despite this long history, the devices being used have changed very little. In fact, current PNS technology was developed...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/000434666
EISBN: 978-3-318-02809-6
... Abstract Peripheral nerve stimulation (PNS) generally refers to stimulation of a named nerve via direct placement of a lead next to the nerve either via a percutaneous or open approach; in peripheral nerve field stimulation (PNFS), leads are subcutaneously placed to stimulate the region...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/000434667
EISBN: 978-3-318-02809-6
... Abstract Pain in extremities may occur in a variety of central and peripheral neuropathic and nociceptive syndromes, some of which may respond to central neuromodulation procedures. Peripheral neuromodulation techniques, either as a stand-alone therapy or as an adjuvant to spinal cord...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/000434669
EISBN: 978-3-318-02809-6
... Abstract Some of the more common peripherally mediated pain disorders are postamputation stump pain and phantom pain. These disabling conditions have proven difficult to treat. Here we aim to illustrate an option to treat postamputation pain using peripheral neurostimulation techniques...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/000434670
EISBN: 978-3-318-02809-6
... or elbow, ankle or knee to target specific peripheral nerves. There is no need for creating strain-relief ‘loops' in subcutaneous leads to accommodate the large ranges of motion associated with normal joint biomechanics. Thus, a percutaneous ‘injectable' implantation of a short contact array becomes...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/000434674
EISBN: 978-3-318-02809-6
... Abstract The number of peripheral nerve stimulation (PNS) indications, targets, and devices is expanding, yet the development of the technology has been slow because many devices used for PNS do not have formal regulatory approval. Manufacturers have not sought Food and Drug Administration (FDA...
Book
Book Cover Image
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
10.1159/isbn.978-3-318-02809-6
EISBN: 978-3-318-02809-6
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000362429
EISBN: 978-3-318-02600-9
... Abstract The identification of peripheral biomarkers for schizophrenia is of great clinical importance, with the potential to considerably improve its diagnosis, treatment and prognosis. However, despite intense research efforts and the discovery of several potential candidates for markers...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358178
EISBN: 978-3-318-02600-9
... the exact nature of the constituents of cells, organs and tissues, and to quantify their levels, biological psychiatric research has produced a wealth of data on blood and other peripheral tissues. Notwithstanding an amount of suggestive evidence for depression biomarkers produced by many investigators...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 28
Published: 27 February 2013
10.1159/000346362
EISBN: 978-3-318-02311-4
... Abstract Evidence suggests that inflammation, an innate immune response facilitating recovery from injury and pathogenic invasion, is positively associated with age-related cognitive decline and may play a role in risk for dementia. Physiological pathways linking the peripheral immune...