... cyst and biliary tract carcinoma. The pancreas consists embryologically of theventral and dorsal anlagen, and is divided into two pancreata by the distribution of pancreaticpolypeptide (PP)-islets. Anomalies based on two pancreata are pancreas divisum and annularpancreas. ...

... is a rare malformation, and it is generally accepted that the ring formationoriginates from a single ventral pancreas, as suggested by Lecco. However, an annularpancreas may also originate from paired ventral pancreata, thus supporting Baldwin’shypothesis. Here, we attempt to clarify the pathogenesis...

... in January 1923. The challenges were 2-fold: supply of raw bovine or porcine pancreata and the need to use large amounts of alcohol. Despite this, in February the MRC accepted the results of the studies and the first British-made insulin was supplied to hospitals on April 12, 1923 [ 16 ]. The demand...

... and histological evaluation of pancreata from patients with a mitochondrial gene mutation associated with impaired insulin secretion. Biochem Biophys Res Commun 1999;259:149-156. 18. Gebhart SS, Shoffner JM, Koontz D, Kaufman A, Wallace D: Insulin resistance associated with maternally inherited diabetes...

... segment. Am J Transplant 2013;13:2550-2557. 46. Berney T, Johnson PR: Donor pancreata: evolving approaches to organ allocation for whole pancreas versus islet transplantation. Transplantation 2010;90:238-243. 47. Merani S, Shapiro AM: Current status of pancreatic islet transplantation. Clin Sci...

..., he wrote: “In order to obtain a pancreatic preparation that is not too toxic, all proteins of the pancreas must be removed” [ 3 ]. At first, Zülzer tried to obtain pancreata from the slaughterhouse, but this proved to be very difficult. Then he came up with the idea of sacrificing large dogs...

... mutations than do healthy controls [ 6 ]. Suboptimal CFTR function causes impaired epithelial ion transport, and may result in hyperviscous pancreatic secretions that may encounter difficulty in draining from pancreata with divisum anatomy. Endoscopic access to the dorsal pancreatic duct...

... in diabetic pregnancy. Recently, decreased autophagy was demonstrated in term placentae and pancreata of stillborn offspring of gestational diabetes mellitus pregnancies [ 62 ], thereby demonstrating the importance of this mechanism in diabetic gestation. Hampered autophagy may be a bridging process which...

... mitochondrial DNA mutation in single pancreatic beta cells. Diabetologia 2003;46:296-299. 17. Otabe S, Yasuda K, Mori Y, Shimokawa K, Kadowaki H, Jimi A, et al: Molecular and histological evaluation of pancreata from patients with a mitochondrial gene mutation associated with impaired insulin secretion...

... within this region show differential temporal imprinting status between adult and fetal pancreata and genotype-specific methylation status [ 24 ]. Importantly, genome-wide epigenetic maps can be overlaid with disease-associated SNPs to suggest variants that regulate gene activity, and variants from...

... segment. Am J Transplant 2013;13:2550-2557. 46. Berney T, Johnson PR: Donor pancreata: evolving approaches to organ allocation for whole pancreas versus islet transplantation. Transplantation 2010;90:238-243. 47. Merani S, Shapiro AM: Current status of pancreatic islet transplantation. Clin Sci...

..., a variety of exogenous food toxins, pancreatic duct anomalies and a possible genetic predisposition. Diabetes is usually severe and insulin required, although histopathological and immunohistochemical studies have documented a partial preservation of insulin-positive cells in pancreata of patients...