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... Abstract Increasing evidence indicates that airway remodeling plays an important part in asthmapathogenesis. However, mechanisms underlying airway remodeling are not yet fully elucidated.Plasminogen activator inhibitor (PAI)-1 is the main inhibitor of the fibrinolytic system and isknown to play...

... Abstract Adrenal insufficiency (AI) is a potentially life-threatening condition and it is of utmost importance to identify and adequately manage affected individuals. Diagnosis is often delayed, probably partly because diseases of the adrenal or pituitary region that cause primary AI (PAI...

... by a disease in the adrenal cortex itself called primary AI (PAI), or by lack of stimulation by adrenocorticotropic hormone (ACTH), named secondary AI (SAI). The 2 forms have lack of cortisol and adrenal androgens in common, but differ in relation to aldosterone which is deficient in PAI, but adequately...