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Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441875
EISBN: 978-3-318-05651-8
... in allergic rhinitis. The allergic response is a complex process involving interactions among several chemical mediators. These mediators, namely histamine [ 1 ], bradykinin [ 2 ], cysteinyl leukotrienes (CysLTs) [ 2 ], platelet-activating factor (PAF) [ 3 ], prostaglandin D 2 (PGD 2 ) [ 4...
Book Chapter
Published: 05 December 1990
10.1159/000419704
EISBN: 978-3-318-05025-7
... Abstract A method was developed to study the interaction of platelets and leukocytes on PAF - or LPS - induced pulmonary obstruction in rats and to evaluate drug effects on lung microembolization. Following injection of 51Chromium labelled homologous platelets into urethane-anesthetized rats...
Book Chapter
Series: Progress in Respiratory Research
Volume: 39
Published: 31 August 2010
10.1159/000320821
EISBN: 978-3-8055-9567-4
...The target Leukotrienes, prostaglandins and platelet activating factor (PAF) have been implicated to various extents in asthma pathophysiology ( Fig. 1 ). For example, the leukotrienes are known to have profound biochemical and physiological effects even in picomolar concentrations, including...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 95
Published: 02 June 2010
10.1159/000315939
EISBN: 978-3-8055-9442-4
...-mediated anaphylaxis in the mouse model [ 23 ]. Two distinct pathways of systemic anaphylaxis: (a) in the classical pathway, mast cells, IgE and histamine play important roles, and by contrast (b) in the alternative pathway, basophils, IgG and PAF play the major roles. Fig. 1...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
EISBN: 978-3-318-05651-8
... A, Lorini M, Bianco A, Miadonna A: Study of the effect of paf-acether on human nasal airways. Allergy 1991;46:466-471. 19. Austin CE, Foreman JC: The effect of platelet-activating factor on the responsiveness of the human nasal airway. Br J Pharmacol 1993;110:113-118. 20. Turner PJ, Dear JW, Foreman...
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Series: Progress in Applied Microcirculation
Volume: 7
Published: 13 June 1985
10.1159/isbn.978-3-318-04066-1
EISBN: 978-3-318-04066-1
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 33
Published: 14 October 2013
10.1159/000351889
EISBN: 978-3-318-02459-3
... of the first outpatient or admission day. ECG monitoring, Holter ECG and specific blood tests such as brain natriuretic peptide and D-dimer are also simultaneously recommended to confirm cardioembolic etiology in specialized clinics. To detect paroxysmal AF (PAF), repeated, long monitoring ECG is essential...
Book
Book Cover Image
Published: 04 July 1985
10.1159/isbn.978-3-318-04669-4
EISBN: 978-3-318-04669-4
Book Chapter
Series: Progress in Respiratory Research
Volume: 42
Published: 13 March 2015
EISBN: 978-3-318-02657-3
.... Bethesda, National Cancer Institute, 2009, chapt 8. 2. Pergadia ML, Der-Avakian A, D'Souza MS, Madden PAF, Heath AC, Shiffman S, Markou A, Pizzagalli DA: Association between nicotine withdrawal and reward responsiveness in humans and rats. JAMA Psychiatry 2014;71:1238-1245. 3. Gilbert DG: Smoking...
Book Chapter
Series: Current Problems in Dermatology
Volume: 40
Published: 10 February 2011
EISBN: 978-3-8055-9616-9
...: 36-40 8. Schnuch A: Der IVDK - eine kurze Synopsis. Akt Dermatol 2009; 35: 94-98 9. Schnuch A: PAFS : population-adjusted frequency of sensitization. I. Influence of sex and age. Contact Dermatitis 1996; 34: 377-382 10. Schnuch A Geier J Uter W Frosch PJ Lehmacher W Aberer W...
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Series: Chemical Immunology and Allergy
Volume: 44
Published: 19 October 1988
10.1159/isbn.978-3-318-01525-6
EISBN: 978-3-318-01525-6
Book Chapter
Published: 05 December 1990
10.1159/000419684
EISBN: 978-3-318-05025-7
... are elicited by FMLP, ADP and PAF in a concentration-dependent manner, due to the activation and aggregation of neutrophils (PMN) and platelets. These effects can be antagonized by exogenously applied adenosine, PGE1 and PGE2 in physiological concentrations. Cultured vascular endothelial cells also inhibit...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 101
Published: 21 May 2015
10.1159/000371702
EISBN: 978-3-318-02341-1
... of platelet-activating factor (PAF)-acetylhydrolase are associated with an increased risk of severe, life-threatening anaphylaxis [ 9 ]. Table 2 Risk factors for anaphylaxis and anaphylaxis-related death Symptoms of food reactions typically begin within seconds to hours after the ingestion...
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Series: Chemical Immunology and Allergy
Volume: 49
Published: 21 March 1990
10.1159/isbn.978-3-318-01627-7
EISBN: 978-3-318-01627-7