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Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 39
Published: 03 August 2016
EISBN: 978-3-318-05865-9
... to prevent epilepsy or to improve the disease. Summary: This chapter reviews new data on patterns of epilepsy with remission and relapse, prognostic factors for seizure outcome, and innovative patient-related outcome measures. Applying this knowledge presents opportunities to improve the drug treatment...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 54
Published: 17 December 2021
EISBN: 978-3-318-06791-0
.... In this chapter, we shall discuss hypothalamic-pituitary morbidity and outcome of childhood-onset craniopharyngioma patients and future perspectives for improvement. Introduction Craniopharyngioma (CP) is a histologically low-grade tumor (WHO grade 1) of the sellar/parasellar region, which has...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 22
Published: 11 February 2020
EISBN: 978-3-318-06621-0
... Abstract This section gives a brief overview of exposure assessment and current outcome definitions in neonatology. Although the comparison of exposure and outcome data is a cornerstone of modern neonatology, patient-focused outcome definitions which were defined by the United States Food...
Book Chapter
Series: Frontiers in Diabetes
Volume: 28
Published: 03 January 2020
EISBN: 978-3-318-06612-8
..., the hyperglycemia and adverse pregnancy outcome (HAPO) study provided the best evidence base to support answers to some of these questions – yet, some remain unsolved and others are still a matter of debate. Translating clinical evidence to practice guidelines is not a pure matter of science, but other...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
EISBN: 978-3-318-06341-7
... Abstract It is well established that nutrition during the first 1,000 days of life can have a long-term effect on growth, metabolic outcome, and long-term health. We review the long-term anthropometric follow-ups of children with risk of later morbidity: (a) very-low-birth-weight (VLBW) infants...
Book Chapter
Series: Endocrine Development
Volume: 33
Published: 28 June 2018
EISBN: 978-3-318-06143-7
... to a specific condition, such as coexisting autoimmune disorders or following irradiation. When patients are transferred from paediatric to adult services, the aim is to optimize care continuity, clinical and biological outcomes, and the quality of life of the individuals such that they become adept at self...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 39
Published: 03 August 2016
EISBN: 978-3-318-05865-9
... for the evaluation of outcomes and for the critical appraisal of findings. Summary: In stroke research, outcomes are mainly represented by composite end points focusing on the occurrence of cardiovascular and cerebrovascular events in trials on primary and secondary prevention and by measures of recovery...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 84
Published: 18 January 2016
EISBN: 978-3-318-05599-3
... Abstract Preterm birth and survival rates are rising globally, and consequently there is a growing necessity to safeguard life-long health. Epidemiological and other studies from around the world point to a higher risk of adverse adult health outcomes following preterm birth. These reports...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 37
Published: 17 November 2015
EISBN: 978-3-318-05597-9
... Abstract Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 15% of all strokes and is a leading cause of disability, with a one-month mortality rate of 40%. Whereas factors predicting short-term mortality are well known, data regarding long-term outcome are scarce...
Book Chapter
Series: Fast Facts Collection 2006-2015
Published: 09 November 2015
EISBN: 978-1-910797-09-9
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 76
Published: 11 February 2015
EISBN: 978-3-318-02787-7
... Abstract Velopharyngeal insufficiency (VPI) affects speech, swallowing, and many psychosocial aspects of life in a way best measured by quality-of-life (QOL) instruments. QOL instruments are patient-reported outcome instruments that provide a method of measuring the value that patients place...
Book Chapter
Series: Endocrine Development
Volume: 26
Published: 15 September 2014
EISBN: 978-3-318-02721-1
... Abstract Screening for a disease begins a process that should lead to confirmation of the diagnosis, establishment of the etiology, optimal treatment and documentation of outcome. In newborns referred for an elevated thyroid-stimulating hormone (TSH) level on the screening specimen, a detailed...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 29
Published: 23 September 2013
EISBN: 978-3-318-02464-7
... and quality of life. From this perspective, recent literature has considered duration of illness (DI) and duration of untreated illness (DUI), two important variables influencing outcome in many psychiatric conditions including anxiety disorders. The DUI has been defined as the interval between the onset...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 106
Published: 12 February 2013
EISBN: 978-3-318-02266-7
... be associated with later health outcomes. Different studies have shown a reduced growth in infants with symptomatic allergy to cow's milk (expressed with atopic eczema) during the first year of life. Differences in weight and length progression between atopic infants and healthy children are significant from...
Book Chapter
Series: Endocrine Development
Volume: 23
Published: 26 November 2012
EISBN: 978-3-318-02245-2
... for the diagnosis of GHD and what then is the ultimate goal of MRI examination? Is MRI phenotype imaging informative? Does a diagnosis of MRI phenotype affect the work-up of patients with GHD? Can MRI phenotype predict the outcome of patients with GHD? And, finally, what is the contribution of these MRI findings...
Book Chapter
Series: Frontiers of Oral Biology
Volume: 16
Published: 27 June 2012
EISBN: 978-3-318-02108-0
... outcomes are constantly reviewed as new evidence unfolds but for many children born with a cleft, basic care will be more rapidly improved through examination of quality of outcomes than the higher level scientific exploration of gene-environment interactions and clinical trials. There are good examples...