1-20 of 128 Search Results for

omeprazole

Sort by
Book Chapter
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
10.1159/000350626
EISBN: 978-3-318-02416-6
... Abstract Proton pump inhibitors (PPIs), such as omeprazole, lansoprazole, rabeprazole, esomeprazole, and pantoprazole, are metabolized by cytochrome P450 2C19 (CYP2C19) in the liver. There are genetic differences in the activity of this enzyme. The genotypes of CYP2C19 are classified into four...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
...: Continuous intravenous infusion of omeprazole in elderly patients with peptic ulcer bleeding. Results of a placebo-controlled multicenter study. Scand J Gastroenterol 1997;32:328-333. 5. Schaffalitzky de Muckadell OB, Havelund T, Harling H, Boesby S, Snel P, Vreeburg EM, et al: Effect of omeprazole...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
10.1159/000350629
EISBN: 978-3-318-02416-6
... treatment with tNSAIDs. They have all shown similar results, with PPIs being superior to H 2 -RAs in healing tNSAID-induced gastroduodenal lesions. A large multicenter study (n = 541) compared two doses of omeprazole (20 and 40 mg/day) with ranitidine (40 mg/day), showing PPI to be more effective...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
10.1159/000350631
EISBN: 978-3-318-02416-6
... with ranitidine and triple therapy with bismuth, metronidazole, and tetracycline [ 10 ]. Inhibition of acid secretion by a PPI, omeprazole, given twice a day in combination with amoxicillin has achieved eradication rates as high as those seen with classical triple therapy [ 11 ]. Classical triple therapy...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
..., Tulassay Z, Juhasz L, Racz I, Howard JM, van Rensburg CJ, et al: A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-Associated Ulcer Treatment (ASTRONAUT) study group. N Engl J Med...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
... the omeprazole dose (40 mg b.d. vs. 20 mg b.d.) in dual therapy with amoxicillin increases the cure rate of Helicobacter pylori infection in duodenal ulcer patients. Aliment Pharmacol Ther 1997;11:515-522. 12. Lind T, Veldhuyzen ZS, Unge P, et al: Eradication of Helicobacter pylori using one-week triple...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
... omeprazol treatment. Gut 1996;39:649-653. 3. Gillen D, Wirz AA, Ardill JE, et al: Rebound hypersecretion after omeprazole and its relation to on-treatment acid suppression and Helicobacter pylori status. Gastroenterology 1999;116:239-247. 4. Gillen D, Wirz AA, Neithercut WD, et al: Helicobacter...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
10.1159/000350632
EISBN: 978-3-318-02416-6
... are both high-dose administration, or that intravenous pantoprazole does not actually produce the same benefit as omeprazole or esomeprazole. A much larger study from China produced a quite different result. When 875 patients with peptic ulcer bleeding were randomized to receive either the standard regimen...
Book
Book Cover Image
Series: Progress in Basic and Clinical Pharmacology
Volume: 11
Published: 19 February 2004
10.1159/isbn.978-3-318-01034-3
EISBN: 978-3-318-01034-3
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
... Pharmacol Ther 1996;60:661-666. 11. Xie HG, Kim RB, Stein CM, et al: Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent. Br J Clin Pharmacol 1999;48:402-408. 12. Furuta T, Ohashi K, Kosuge K, et al: CYP2C19 genotype status and effect of omeprazole...
Book
Book Cover Image
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
10.1159/isbn.978-3-318-02416-6
EISBN: 978-3-318-02416-6
Book
Book Cover Image
Series: Progress in Basic and Clinical Pharmacology
Volume: 11
Published: 10 November 1999
10.1159/isbn.978-3-318-00233-1
EISBN: 978-3-318-00233-1
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
.... Veldhuyzen van Zanten SJ, Chiba N, Armstrong D, et al: A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in Helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study. Am J Gastroenterol 2005;100:1477-1488. 23. Sakurai K, Nagahara A, Inoue K, et al...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
10.1159/000350635
EISBN: 978-3-318-02416-6
..., an increase in both basal and maximal acid levels was observed 14 days after treatment [ 2 , 3 , 4 ]. Waldum et al. [ 2 ] compared gastric acid secretion before omeprazole administration and 14 days after withdrawal of the drug following a 3-month therapy in patients with gastroesophageal reflux disease...
Book
Book Cover Image
Series: Frontiers of Gastrointestinal Research
Volume: 20
Published: 04 December 1991
10.1159/isbn.978-3-318-03643-5
EISBN: 978-3-318-03643-5
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
... CB, Heijerman HG: Effect of omeprazole 40 mg once daily on intraduodenal and intragastric pH in H. pylori -negative healthy subjects. Dig Dis Sci 1997;42:2304-2309. 51. Cai J, Zhou W, Luo HS, Peng LV: Effect of proton pump inhibitor on amylase release from isolated pancreatic acini. In Vitro...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
..., Carlsson E, Lindberg P: A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole. Nat Rev Drug Discov 2003;2:132-139. 5. Sjöstrand SE, Ryberg B, Olbe L: Stimulation and inhibition of acid secretion in the isolated guinea pig gastric mucosa. Acta Physiol Scand 1978;184(suppl...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 32
Published: 23 September 2013
EISBN: 978-3-318-02416-6
.... Pharmacotherapy 2008;28:951-959. 8. Roux C, Briot K, Gossec L, Kolta S, Blenk T, Felsenberg D, Reid DM, Eastell R, Glüer CC: Increase in vertebral fracture risk in postmenopausal women using omeprazole. Calcif Tissue Int 2009;84:13-19. 9. de Vries F, Cooper AL, Cockle SM, van Staa TP, Cooper C: Fracture...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 27
Published: 13 November 2009
EISBN: 978-3-8055-9309-0
... 2006;23:985-995 44. Khuroo MS, Yattoo GN, Javid G, Khan BA, Shah AA, Gulzar GM, Sodi JS: A comparison of omeprazole and placebo for bleeding peptic ulcer. N Engl J Med 1997;336:1054-1058 45. Lau JY, Sung JJ, Lee KK, Yung MY, Wong SK, Wu JC, Chan FK, Ng EK, You JH, Lee CW, Chan AC, Chung SC: Effect...