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oligosaccharide

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Book Chapter
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
10.1159/000518201
EISBN: 978-3-318-06296-0
... Human milk oligosaccharides Secretors Nonsecretors Synbiotics Infant health Key Messages Human milk oligosaccharides (HMOs) are a group of more than 150 different unconjugated carbohydrates (glycans), and their composition varies greatly between women and is dynamic over...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505338
EISBN: 978-3-318-06685-2
... norovirus strains. In our current work, we tried to decipher the HBGA specificity of the most prevalent and clinically relevant norovirus GII.4 subfamily (Sydney 2012, JX459908) and its preferences for human milk oligosaccharides (HMOs) as potential anti-infectives. The structural evidence provided can...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
10.1159/000455401
EISBN: 978-3-318-06031-7
... of exclusive breast feeding and the absence of human breast milk oligosaccharides in cow's milk- and soy milk-based formulas were noted. David Dallas and J. Bruce German (Oregon State University and University of California, Davis, USA) began with an elegant presentation highlighting the complexity...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505339
EISBN: 978-3-318-06685-2
... Abstract Oligosaccharides are a group of complex glycans that are present in the milk of most mammals. However, human milk is unique as the concentrations of human milk oligosaccharides (HMOs) are much higher than those of other mammals, and their structural composition is more complex...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
10.1159/000455400
EISBN: 978-3-318-06031-7
... Abstract Human milk oligosaccharides are key components of human milk and appear in various compositions and concentrations in all human milks. In regulatory sense human milk oligosaccharides are classified as novel foods or novel food ingredients requiring safety assessment. In addition...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519390
EISBN: 978-3-318-07015-6
... determinants, and were associated with short- and long-term outcome. In another study, the effects of caesarean birth on infant gut microbiota could be alleviated by human milk oligosaccharides (HMOs) in mothers’ milk. In addition, 58 infants fed with a formula enriched with 2 HMOs had microbiota closer...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490306
EISBN: 978-3-318-06341-7
... Abstract Human milk oligosaccharides (HMOs) are the third most abundant component of human milk. So far, more than 150 different and structurally distinct HMOs have been identified. HMO composition varies substantially between women, but remains fairly constant over the course of lactation...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
10.1159/000455398
EISBN: 978-3-318-06031-7
... Abstract It is a great success that biotechnological means are available today to produce amounts of single human milk oligosaccharides (HMOs) in a purity which allows performing metabolic and functional studies even in humans. As recent data indicate that there is a link between the Lewis...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490292
EISBN: 978-3-318-06341-7
... Abstract Human milk oligosaccharides (HMOs) are elongations of the milk sugar lactose by galactose, N-acetylglucosamine, fucose; and sialic acid. The HMO composition of breast milk is strongly influenced by polymorphisms of the maternal fucosyltransferases, FUT2 and FUT3, and by the stage...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 97
Published: 12 May 2023
10.1159/000528992
EISBN: 978-3-318-07170-2
... Abstract Human milk contains all nutritive and bioactive compounds to give infants the best possible start in life. Human milk bioactives cover a broad range of components, including immune cells, antimicrobial proteins, microbes, and human milk oligosaccharides (HMOs). Over the last decade...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519388
EISBN: 978-3-318-07015-6
... Abstract The benefits of breastfeeding, such as reduced risk of gastrointestinal and respiratory tract infections, depend largely on the presence of bioactive compounds in breast milk, including human milk oligosaccharides (HMOs). The presence of HMOs represents one of the largest differences...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 62
Published: 12 August 2008
10.1159/000146322
EISBN: 978-3-8055-8554-5
... Abstract Human milk contains a high concentration of diverse soluble oligosaccharides, carbohydratepolymers formed from a small number of monosaccharides. Novel methods combiningliquid chromatography with high resolution mass spectrometry have identifiedapproximately 200 unique oligosaccharides...
Book Chapter
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519405
EISBN: 978-3-318-07015-6
... in particular. At the same time, challenges create opportunities for potential interventions to help shape healthy microbial communities. Interventions include the use of human milk, the use of specific human milk bioactives like human milk oligosaccharides (HMOs), as well as the use of probiotics...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
EISBN: 978-3-318-06296-0
...References References 1. Bode L. Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology. 2012;22:1147–62. 2. Kobata A. Structures and application of oligosaccharides in human milk. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86:731–47. 3. Azad MB, Robertson B, Atakora F...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 97
Published: 12 May 2023
EISBN: 978-3-318-07170-2
...References References 1. Sprenger N, Tytgat HL, Binia A, et al. Biology of human milk oligosaccharides: from basic science to clinical evidence. J Hum Nutr Diet. 2022;35(2):280–99. 2. Korpela K, de Vos WM. Early life colonization of the human gut: microbes matter everywhere. Curr Opin...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
EISBN: 978-3-318-06685-2
...References References 1. Bode L: Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology 2012;22:1147–1162. 2. Jantscher-Krenn E, Bode L: Structure-function relationships of human milk oligosaccharides. Adv Nutr 2012;3:383S–391S. 3. Azad MB, Robertson B, Atakora F, et...