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Book
Book Cover Image
Series: Developments in Ophthalmology
Volume: 61
Published: 27 May 2021
10.1159/isbn.978-3-318-06854-2
EISBN: 978-3-318-06854-2
Book
Series: Concepts in Toxicology
Volume: 4
Published: 01 September 1987
Book Chapter
Book Chapter
Series: Progress in Neurological Surgery
Volume: 34
Published: 28 May 2019
10.1159/000493078
EISBN: 978-3-318-06422-3
... conditions includes eye metastases, advanced glaucoma, age-related macular degeneration, hemangioblastoma, pseudotumors, and vegetative pain. Radiosurgery of ocular disorders depends on close cooperation with ophthalmologists who are decisive in determining whether radiosurgery is indicated and in the follow...
Book Chapter
Series: Developments in Ophthalmology
Volume: 59
Published: 28 April 2017
10.1159/000458487
EISBN: 978-3-318-06040-9
... Abstract There is a large body of evidence from clinical and experimental studies indicating that the long-term use of topical drugs may induce ocular surface changes, causing ocular discomfort, dry eye, conjunctival inflammation, subconjunctival fibrosis, corneal surface impairment...
Book
Book Cover Image
Series: ESASO Course Series
Volume: 7
Published: 06 April 2016
10.1159/isbn.978-3-318-05619-8
EISBN: 978-3-318-05619-8
Book Chapter
Series: Developments in Ophthalmology
Volume: 57
Published: 04 April 2016
10.1159/000442498
EISBN: 978-3-318-05820-8
... in axial elongation after cataract extraction, the magnitude of this effect is much less than what has been reported in animal models. Choosing an intraocular lens (IOL) power for implantation into a child's eye is complicated by continued ocular growth, the inaccuracy of IOL power calculation formulas...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431129
EISBN: 978-3-318-05565-8
... Abstract Systematic study of the mechanisms underlying pathological ocular neovascularization has yielded a wealth of knowledge about pro- and anti-angiogenic factors that modulate diseases such as neovascular age-related macular degeneration. The evidence implicating vascular endothelial...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431131
EISBN: 978-3-318-05565-8
... for understanding pharmacotherapeutics that may be useful in treating retinal disease. History Like the field of immunology, the field of ocular immunology and inflammation has grown rapidly over the past years. This chapter covers broad concepts in immunology important in ocular disease as well as basic...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000434694
EISBN: 978-3-318-05565-8
... Abstract Hydrogel as an ocular drug delivery platform holds great potential. Hydrogels are three-dimensional, hydrophilic, polymeric networks capable of absorbing large amounts of water or biological fluids. They have the ability to swell in an aqueous solvent system, holding solvents within...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431195
EISBN: 978-3-318-05565-8
... of the lacrimal drainage system, contaminated eye drops, contact lens wear, a contralateral ocular prosthesis and active infection elsewhere in the body. Intraoperative risk factors include prolonged surgery, secondary IOL implantation, posterior capsular rupture, vitreous loss, iris prolapse, contaminated...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000438953
EISBN: 978-3-318-05565-8
..., the suppression was greater than that achieved with anti-VEGF DARPin alone. Similarly, strong suppression of retinal NV was also achieved with 1.85 µg of anti-PDGF-BB DARPin. These findings suggest that PDGF is a valid target for the treatment of ocular NV. Several clinical trials evaluating the role of PDGF...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000434698
EISBN: 978-3-318-05565-8
... Abstract Ocular gene therapy involves the introduction of an exogenous gene product to a host's cellular and genetic machinery for endogenous production of a desired gene product. The eye represents an ideal target organ due to its easy visibility and accessibility, and several trials have...
Book Chapter
Book: Cornea
Series: ESASO Course Series
Volume: 6
Published: 11 August 2015
10.1159/000381489
EISBN: 978-3-318-05453-8
... Abstract The ocular surface (OS) is a functional unit comprising the eyelids and blink reflexes, tear film and tear glands, the conjunctival mucus membrane and substantia propria, and the corneal epithelium and Bowman's zone. Its health is crucial for vision. The OS can be affected by a variety...
Book Chapter
Series: ESASO Course Series
Volume: 1
Published: 24 May 2012
10.1159/000336684
EISBN: 978-3-8055-9991-7
... Abstract Ocular ischemic syndrome (OIS) is caused by reduction of global blood flow to the eye. OIS is usually related to unilateral or bilateral atherosclerotic disease of the internal carotid artery, which can produce anterior and/or posterior segment ischemia, leading to neovascularization...
Book Chapter
Series: Developments in Ophthalmology
Volume: 50
Published: 20 April 2012
10.1159/000334791
EISBN: 978-3-8055-9938-2
... Abstract There is a large body of evidence from clinical and experimental studies that the long-term use of topical drugs may induce ocular surface changes, causing ocular discomfort, dry eye, conjunctival inflammation, subconjunctival fibrosis, corneal surface impairment, and, as a consequence...
Book Chapter
Book: Anti-VEGF
Series: Developments in Ophthalmology
Volume: 46
Published: 13 August 2010
10.1159/000320006
EISBN: 978-3-8055-9530-8
... Abstract Angiogenesis is defined as the formation of new blood vessels from the existing vasculature. It is a highly coordinated process occurring during development of the retinal vasculature, ocular wound healing, and in pathological conditions. Complex interactions are involved between non...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315014
EISBN: 978-3-8055-9419-6
... to be in enhancing wound healing by promoting a process called ‘restitution’. Studies evaluating TFF3 properties and effects at the ocular surface using in vivo as well as in vitro models have revealed a pivotal role of TFF3 in corneal wound healing. Subsequent studies in osteoarthritic cartilage seem to draw...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315016
EISBN: 978-3-8055-9419-6
... Abstract The ocular surface is in constant contact with the environment (e.g. when using one’s fingers to insert a contact lens) and thus also with diverse bacteria, bacterial components and their pathogen associated molecules. Dysfunctions of the tear film structure or decreased moistening...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315024
EISBN: 978-3-8055-9419-6
... Abstract Purpose: The structure of the lid margin is insufficiently understood and defined, although it is of obvious importance in ocular surface integrity. Methods: The structure and function of the different zones of the lid margin are explained with a focus on dry eye disease. Results...