1-20 of 620 Search Results for

nmol

Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Book Chapter
Series: Frontiers of Hormone Research
Volume: 37
Published: 17 November 2008
10.1159/000175841
EISBN: 978-3-8055-8623-8
... testosterone are found to be around the lower limit of normal (˜9.0 nmol/l; µg/l=nmol/lx0.288), some measure of bioactive testosterone should be sought. This may be a free (non-protein-bound) or bioavailable (free plus albumin-bound) testosterone and may be measured (laborious and time-consuming and therefore...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 49
Published: 26 April 2018
10.1159/000485999
EISBN: 978-3-318-06335-6
... studies suggest a bidirectional pathogenic relationship. In fact, reduced T (-2.21 [-2.43 to -1.98] nmol/L) at baseline predicts incident MetS. On the other hand, MetS at study entry increases the risk of developing HG (OR 2.46 [1.77-3.42]). The bidirectional pathogenic link between MetS and HG is further...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 37
Published: 17 November 2008
10.1159/000175839
EISBN: 978-3-8055-8623-8
..., or cardiovascular disease. All these conditions are associated with a high prevalence of hypogonadism. Pharmacological therapy with opiates and corticosteroids are also known to cause hypogonadism. Hypogonadal symptoms are precipitated at different testosterone levels. Total testosterone levels of less than 8 nmol...
Book Chapter
Series: Endocrine Development
Volume: 17
Published: 24 November 2009
10.1159/000262532
EISBN: 978-3-8055-9303-8
... (200 nmol/l) with serum cortisol ≤5 µg/dl (140 nmol/l). For the insulin tolerance test [ 8 ], 0.1 U/kg of human regular insulin was injected and serum cortisol and glucose were measured at baseline and at 30, 60, 90 and 120 min after insulin administration. The test was positive if the cortisol...
Book Chapter
Series: Endocrine Development
Volume: 28
Published: 11 June 2015
10.1159/000381000
EISBN: 978-3-318-05467-5
... published in 2010 [ 2 ] defined a level of 50 nmol/l as meeting the needs of 97.5% of the population, whereas the Endocrine Society Clinical Practice Guideline published in 2011 defined vitamin D deficiency as a level <50 nmol/l, with levels of between 52.5 and 72.5 nmol/l regarded as vitamin D...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 46
Published: 23 May 2016
10.1159/000443913
EISBN: 978-3-318-05840-6
... function. It is easy and quick to perform. Very low (<100 nmol/l) or high (>500 nmol/l) morning cortisol levels obviate the need for dynamic tests. Alternatives to plasma total cortisol are free plasma cortisol and salivary cortisol measurement in case of suspected increased or decreased CBG...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
10.1159/000486065
EISBN: 978-3-318-06339-4
... Abstract North American and European authorities have identified thresholds up to 50 nmol/L serum 25-hydroxyvitamin D (25[OH]D) as optimal for pediatric vitamin D status. These recommendations are relative to skeletal endpoints, as vitamin D plays a pivotal role in bone mineral content (BMC...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 118
Published: 24 April 2018
10.1159/000484391
EISBN: 978-3-318-06253-3
... status [ 9 ]) below a threshold which has been variably suggested to range from <12.5 to <50 nmol/L [ 10 ]. Most authoritative agencies briefed with establishing either dietary recommendations for vitamin D or guidelines for prevention of vitamin D deficiency have used <25/30 nmol/L...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494906
EISBN: 978-3-318-06471-1
... serum testosterone concentrations above 7 nmol/L could indicate an androgen-secreting tumor. Other ovarian and adrenal androgens should be determined and functional endocrine testing including low-dose dexamethasone suppression test, gonadotrophin-releasing hormone (GnRH) agonist test, imaging methods...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 40
Published: 19 October 2012
10.1159/000342179
EISBN: 978-3-318-02239-1
... follicular phase 17-hydroxyprogesterone level should be used as a screening tool, regardless of the presence of polycystic ovaries or metabolic dysfunction; in the case of doubt, an ACTH stimulation test is recommended. Levels above 10 ng/ml (30 nmol/l), either basal or after stimulation should be considered...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 30
Published: 22 June 2012
10.1159/000338428
EISBN: 978-3-318-02184-4
... (600 nmol i.c.v.). Simultaneously, the noradrenaline content of nucleus tractus solitarii (NTS) decreased from 1,881 ± 89 to 1,439 ± 154 pg/mg tissue (p < 0.05) in 6-OH dopamine-treated rats. The results indicate that the integrity of the adrenergic system besides the cholinergic one may also...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
10.1159/000516711
EISBN: 978-3-318-06296-0
... was still prevalent among children [ 1 ]. A global consensus [ 34 ] in 2016 defined vitamin D insufficiency as serum 25OHD between 30 and 50 nmol/L, and deficiency as 25OHD below 30nmol/L. A cross-sectional survey in 2016–2017 suggested that the prevalence of vitamin D insufficiency/deficiency (25OHD <50...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
10.1159/000486086
EISBN: 978-3-318-06339-4
... and prospective studies have demonstrated the association of serum 25[OH]D levels lower than 50 nmol/L (20 ng/mL) with a 30-50% increase in risk of breast, prostate, and colon cancer, as well as a higher mortality from such diseases [ 1 ]. Regarding in particular the immune system, vitamin D deficiency may have...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 95
Published: 12 January 2021
10.1159/000511507
EISBN: 978-3-318-06866-5
... ]. Although targeted levels of 25-OHD are usually set at 50 nmol/L, it is likely that calcium absorption is only substantially limited at lower levels, such as below 30 nmol/L [ 24, 25 ]. Whether other potential benefits, such as immune function, require higher 25-OHD levels remains uncertain, especially...
Book Chapter
Series: Endocrine Development
Volume: 20
Published: 17 December 2010
10.1159/000321241
EISBN: 978-3-8055-9644-2
... ]. In a study to determine single- dose pharmacokinetics it was shown that the time to reach a clinically significant serum concentration of cortisol (>200 nmol/l) was within 25 min and a peak of 400–450 nmol/l was obtained within 50 min after the 20- mg tablet. Serum cortisol levels remained >200 nmol/l...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 52
Published: 05 February 2019
10.1159/000493239
EISBN: 978-3-318-06383-7
.... In the appropriate clinical context, measurement of morning cortisol may be useful. In a prospective study of patients presenting with euvolemic hyponatremia, 87% of our cohort of 573 patients had 09.00 h plasma cortisol as a screening tool for adrenal insufficiency. Anyone with a plasma cortisol <300 nmol/L (11...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 97
Published: 12 May 2023
10.1159/000529005
EISBN: 978-3-318-07170-2
... and/or have darker skins, which modulates the conversion of inactive to active vitamin D 3 . A review of the global prevalence of vitamin D deficiency highlights the importance of such variables [ 19 ]. Using cutoffs for 25(OH)D levels of <30 nmol/L (12 ng/mL), <50 nmol/L (<20 ng/mL), and <75 nmol...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 46
Published: 23 May 2016
10.1159/000443861
EISBN: 978-3-318-05840-6
..., justifying the rationale for using this test. To enhance the sensitivity of this test, a post-dexamethasone cortisol cut-off of 50 nmol/l at 08.00-09.00 h is recommended, although this at the expense of a lower specificity depending on the population being screened. Around 5% of patients with proven...
Book Chapter
Series: Progress in Respiratory Research
Volume: 39
Published: 31 August 2010
10.1159/000320824
EISBN: 978-3-8055-9567-4
.... Table 1. Examples of patent applications of MMP-9 and/or MMP-12 inhibitors for respiratory diseases. Another broad-spectrum MMP inhibitor, CP-471474, discovered by Pfizer, has also been studied, and has been reported to have IC 50 values of 1170 nmol/L (MMP-1), 0.7 nmol/L (MMP-2), 16 nmol/L...
Book Chapter
Series: Endocrine Development
Volume: 30
Published: 10 December 2015
10.1159/000439329
EISBN: 978-3-318-05637-2
... of hydrocortisone reveal wide interindividual variability in different parameters. After 10-20 mg of oral hydrocortisone, C max varied between 422 and 1,554 nmol/l and area under the curve (AUC) ranged between 1,081 and 5,471 nmol h/l in patients suffering from AI [ 28 ]. A number of factors could account...