Search Results for neuron

... Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of unknown originaffecting primarily motor neurons. The observation that point mutations in the copper/zincsuperoxide dismutase (SOD1) gene are present in some patients with autosomal dominantfamilial ALS (FALS) has...

... Abstract Many proteins first identified in the nervous system were also found to be expressedelsewhere in the body. The text reviews some of these ‘neuronal’ markers and delineatesintersections between nervous and non-nervous tissues on the structural and functional level.Examples are given...

... (swelling-induced extracellular space shrinkage and ephaptic interactions)might be responsible for the hyposmolarity effects on brain excitability. Neuronal volumeconstancy in hyponatremia is preserved by the isovolumetric regulation, relying importantlyon organic osmolytes. Changes in cell volume...

... Abstract Biological tools that are unleashed in malignancies are employed in a controlled mannerduring neuronal development. By default, early embryonic cells would become neuronalstem cells, a path that is blocked by specific signaling pathways. The future nervous systemonly develops where...

... Abstract The multifunctional, hypothalamic hypocretin/orexin (HCRT)-producing neurons regulate an array of physiological and behavioral states including arousal, sleep, feeding, emotions, stress, and reward. How a presumably uniform HCRT neuron population regulates such a diverse set...