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neovascular

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Book Chapter
Series: ESASO Course Series
Volume: 9
Published: 07 June 2017
10.1159/000471825
EISBN: 978-3-318-06068-3
... Abstract Neovascular age-related macular degeneration (AMD) is a disease with the potential to cause significant visual impairment. The hallmark of this disease is the development of angiogenesis originating from the choroid or retina leading to various, potentially blinding, complications...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000438969
EISBN: 978-3-318-05565-8
... Abstract Age-related macular degeneration (AMD) is the leading cause of severe vision loss in individuals over the age of 50 years. Choroidal neovascularization (CNV) is the hallmark of ‘wet' or ‘exudative' AMD, and is responsible for approximately 90% of cases of severe vision loss due to AMD...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431196
EISBN: 978-3-318-05565-8
... Abstract Neovascular glaucoma (NVG) is a secondary ocular pathological condition resulting from a myriad of ocular and systemic conditions with retinal ischemia as a mediator in over 95% of cases. NVG is caused by the growth of a fibrovascular membrane secondary to a local angiogenic stimulus...
Book Chapter
Series: ESASO Course Series
Volume: 4
Published: 27 February 2014
10.1159/000355967
EISBN: 978-3-318-02564-4
... Abstract The purpose of this study was to develop a method of segmentation using ‘en face' spectral domain-optical coherence tomography (SD-OCT) (‘en face' C-scans) to evaluate different patterns of the choroidal neovascular network (CNV) due to age-related macular degeneration (AMD...
Book Chapter
Series: Frontiers in Diabetes
Volume: 20
Published: 24 November 2009
10.1159/000262664
EISBN: 978-3-8055-9276-5
... and protein levels [ 27 ]. These observations suggest that PEDF is an endogenous negative regulator of VEGF in Müller cells, and that regulatory Müller glial functions are important for adjusting the balance between pro-angiogenic and anti-angiogenic mediators during retinal neovascular processes...
Book Chapter
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431194
EISBN: 978-3-318-05565-8
... Abstract Choroidal neovascularization (CNV) is a significant cause of vision loss in all age groups. The most common cause of CNV is age-related macular degeneration (AMD). However, CNV can also occur as a secondary manifestation of various inherited and acquired conditions, including...
Book Chapter
Series: ESASO Course Series
Volume: 4
Published: 27 February 2014
10.1159/000355969
EISBN: 978-3-318-02564-4
... Abstract Choroidal neovascularization (CNV) is one of the most important vision-threatening complications of degenerative myopia, occurring in up to 10% of highly myopic eyes. Optical coherence tomography (OCT) is a noninvasive examination technique, easy to be performed, and well accepted...
Book Chapter
Series: ESASO Course Series
Volume: 11
Published: 28 December 2020
10.1159/000485304
EISBN: 978-3-318-06643-2
... Abstract Neovascular age-related macular degeneration (AMD) is most commonly the result of type 1 choroidal neovascularization (NV) which comprises 60% or more of lesion types in wet AMD. However, intraretinal NV or type 3 NV is the cause of exudative AMD in one-third of cases. Given the small...
Book Chapter
Book Chapter
Book: Anti-VEGF
Series: Developments in Ophthalmology
Volume: 46
Published: 13 August 2010
10.1159/000320010
EISBN: 978-3-8055-9530-8
... Abstract Choroidal neovascularization (CNV) is the most common vision-threatening macular complication in pathologic myopia (PM) being detectable in 4–11% of the affected eyes. Treatment of PM-related CNV is still controversial. Intravitreal injections of antivascular endothelial growth factor...
Book Chapter
Series: ESASO Course Series
Volume: 11
Published: 28 December 2020
10.1159/000504923
EISBN: 978-3-318-06643-2
... Abstract The pathogenesis of type 3 neovascularization has been debated over the past 2 decades. Using high-resolution multimodal imaging including high-density optical coherence tomography (OCT) and OCT angiography (OCTA), it has been illustrated that type 3 neovascularizations originate...
Book Chapter
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442800
EISBN: 978-3-318-05830-7
... Abstract Purpose: To analyze the ability of optical coherence tomography angiography (OCT-A) to detect the presence of myopic choroidal neovascularization (CNV) and to describe structural features of myopic CNV on OCT-A. Methods: Patients with CNV secondary to high myopia (>6...
Book Chapter
Book Chapter
Series: ESASO Course Series
Volume: 11
Published: 28 December 2020
10.1159/000485305
EISBN: 978-3-318-06643-2
... Abstract Long-term type 1 neovascularization (NV) evolution shows different outcomes: stabilization, chronicity, fibrosis, atrophy, hemorrhages, or retinal pigment epithelium (RPE) tears. We do not know the reason why some NVs become stable, bringing to a standstill its evolution and activity...
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442780
EISBN: 978-3-318-05830-7
... Abstract Purpose: To describe the imaging of mixed neovascular age-related macular degeneration (AMD) using optical coherence tomography angiography (OCTA). Methods: Literature review and case series. Results: A review of mixed neovascularization in AMD is discussed, focusing...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000438953
EISBN: 978-3-318-05565-8
... that is activated in retinochoroidal vascular diseases. The mechanism of action, side effects, efficacy, and the potential synergistic role of these agents in combination with other treatment options is discussed. The future of treatment of retinochoroidal vascular diseases, particularly neovascular AMD, has become...
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442776
EISBN: 978-3-318-05830-7
... Abstract Age-related macular degeneration continues to be the leading cause of severe central vision loss in older adults of European descent. Optical coherence tomography angiography (OCT-A) enables more accurate identification of type 1 neovascularization in age-related macular degeneration...
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442777
EISBN: 978-3-318-05830-7
... Abstract Well-defined choroidal neovascularization, known as type 2 neovascularization (NV) or classic NV, is the least representative phenotype of exudative age-related macular degeneration. Clinical aspects of type 2 NV have been widely described in the literature, and to date fluorescein...