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myeloproliferative

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Published: 08 January 2019
10.1159/isbn.978-1-910797-80-8
EISBN: 978-1-910797-80-8
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 17
Published: 29 November 2013
10.1159/000350348
EISBN: 978-3-318-02423-4
... Abstract Paediatric myelodysplasia syndromes (MDS) and myeloproliferative disorders (MPD) are rare and genetically and clinically heterogeneous. This review focuses on recent studies outlining the partially characterised pathogenetic germline and/or acquired genetic changes in these disorders...
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Series: Monographs in Human Genetics
Volume: 17
Published: 02 October 2008
10.1159/000164848
EISBN: 978-3-8055-8654-2
... Abstract The Ras signaling pathway has been extensively studied because of its fundamental role in cancer. This review discusses the occurrence of cancer in persons affected by germline mutations in genes of this pathway. There is a link between Noonan syndrome and myeloproliferative disease...
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Series: Contributions to Oncology
Volume: 41
Published: 29 January 1991
10.1159/000419222
EISBN: 978-3-318-03424-0
... Abstract ZusammenfassungTransiente, neonatale myeloproliferative Störungen (TMDs) wurden bei Neugeborenen mit Down-Syndrom beschrieben und können infolge Hepatosplenomegalie, Hautinfektionen, Leukozytose, Anämie, Thrombozytopenie nicht von akuter Leukämie unterschieden werden. Retrospektiv...
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