Search Results for muscle

... Abstract Skeletal myogenesis begins in the embryo with proliferation and differentiation of muscle progenitor cells that ultimately fuse to form multinucleated myofibers. After midgestation, muscle growth occurs through hypertrophy of these myofibers. The most rapid growth phase occurs...

... by relatively rapid fibrosis of the involved extraocular muscles. This results in a reduced elasticity with preserved or even forced contractility. Clinically the muscle appears stiff and inextensible. Affected patients develop an incomitant strabismus, i.e., the angle of strabismus varies in different...

... predominance of female patients). Tumor cells in aspirates have morphology reminiscent of normal smooth muscle and myofibroblastic cells. An important diagnostic pitfall is low-grade leiomyosarcoma (LMS), which displays more nuclear pleomorphism and coarser chromatin than leiomyoma. Cytologic Features...

... Rhabdomyosarcoma (RMS) is a malignant tumor with differentiation towards skeletal muscle and is the most common sarcoma of childhood. Four main subtypes are recognized in the current WHO classification: embryonal, alveolar, spindle cell/sclerosing, and pleomorphic. The embryonal subtype of RMS...

... Abstract Muscle stem cells, resident beneath the basal lamina of skeletal muscle myofibers, are quiescent precursor cells and are required for normal postnatal growth and repair of skeletal muscles in adulthood. There is clear evidence of functional decline in skeletal muscle tissue during...

... Abstract This chapter reviews current knowledge of the various signaling pathways that cause the glucose transporter isoform 4 (GLUT4)-containing vesicles to translocate from intracellular compartments of skeletal muscle cells to the plasma membrane in response to exercise. Specifically...

... response. Excessive anti-inflammatory measures may impair recovery. Many injuries result in limb immobilization. Immobilization results in muscle loss due to increased periods of negative muscle protein balance from decreased basal muscle protein synthesis and resistance to anabolic stimuli, including...