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Book
Published: 20 June 1983
10.1159/isbn.978-3-318-04955-8
EISBN: 978-3-318-04955-8
Book Chapter
Series: Progress in Tumor Research
Volume: 43
Published: 08 September 2016
10.1159/000447043
EISBN: 978-3-318-05912-0
... us to create biologically driven trials and facilitate early new drug access and the creation of biobank collections to drive our understanding of the biology of cancers in this age group. Involving multiple stakeholders in trial design will facilitate acceptable trials to both healthcare...
Book Chapter
Series: Radiosurgery
Volume: 1
Published: 23 January 1996
10.1159/000425000
EISBN: 978-3-318-04188-0
Book Chapter
Published: 20 June 1983
10.1159/000408043
EISBN: 978-3-318-04955-8
Book Chapter
Series: Contributions to Nephrology
Volume: 200
Published: 07 August 2023
10.1159/000527355
EISBN: 978-3-318-07124-5
... Abstract Sepsis and multiple organ failure (MOF) are characterized by multiple hemodynamic changes and imbalanced immune response of the patient. Oxiris is a highly adsorptive membrane with the ability to remove cytokines and endotoxins, as well as to perform renal replacement therapy. Here we...
Book
Published: 14 March 2023
10.1159/isbn.978-3-318-00502-8
EISBN: 978-3-318-00502-8
Book Chapter
Book: Brain Stem Death: A Chronicle of Three Decades of Search for Its Cellular and Molecular Mechanisms
Series: Translational Research in Biomedicine
Volume: 8
Published: 10 May 2022
10.1159/000522459
EISBN: 978-3-318-07054-5
..., maintained mitochondrial membrane potential, diminished cytosolic level of AIF, and reduced apoptotic cell death. 5.4. Conclusion Mitochondria in the RVLM plays multiple roles during the progression towards brain stem death (Fig. 1 ). Dysfunction of mitochondrial ETC complexes and decrease in Mn-SOD...
Book
Published: 27 May 2021
10.1159/isbn.978-3-318-06799-6
EISBN: 978-3-318-06799-6
Book Chapter
Book: Leksell Radiosurgery
Series: Progress in Neurological Surgery
Volume: 34
Published: 28 May 2019
10.1159/000493055
EISBN: 978-3-318-06422-3
... Abstract Stereotactic radiosurgery (SRS) is an effective treatment for patients with multiple brain metastases. Three decades of increasingly powerful scientific studies have shown that SRS improves outcomes and reduces toxicity when it replaces whole-brain radiation therapy (WBRT). Expert...
Book Chapter
Series: Contributions to Nephrology
Volume: 194
Published: 26 April 2018
10.1159/000485634
EISBN: 978-3-318-06307-3
... Abstract The incidence of the multiple organ dysfunction syndrome (MODS) is rapidly increasing in intensive care units (ICU). It usually combines with sepsis and is the most frequent cause of death in the ICU patients. The nature of the ICU patients has changed in the last years. It includes...
Book Chapter
Series: Endocrine Development
Volume: 32
Published: 21 August 2017
10.1159/000475737
EISBN: 978-3-318-05974-8
... to the complexity of the disease and the redundancy of metabolic regulatory mechanisms that sustain body weight. At the forefront of obesity research is the development of combinational drug therapies that simultaneously target multiple regulatory pathways, which promote dysfunctional metabolism. Recently...
Book
Series: Fast Facts Collection 2017
Published: 09 January 2017
10.1159/isbn.978-1-910797-38-9
EISBN: 978-1-910797-38-9
Book Chapter
Series: Fast Facts Collection 2016
Published: 29 August 2016
10.1159/000491262
EISBN: 978-1-910797-26-6
Book
Series: Fast Facts Collection 2016
Published: 29 August 2016
10.1159/isbn.978-1-910797-26-6
EISBN: 978-1-910797-26-6
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 39
Published: 03 August 2016
10.1159/000445418
EISBN: 978-3-318-05865-9
... Abstract Background: The main objective in the treatment of multiple sclerosis is to prevent or postpone the long-term disability caused by the disease, which in most cases occurs over years. However, most randomized clinical trials (RCTs) assessing the efficacy and safety of disease...
Book Chapter
Published: 02 April 2015
10.1159/000365473
EISBN: 978-3-318-02697-9
... diseases, such as multiple sclerosis, are discussed. The vulnerability of the human neck and its impact on cerebrospinal fluid flow throughout the brain and spine is also linked to properly identifying the craniocervical syndrome given its plethora of symptoms. The advent of MRI and its unique...
Book Chapter
Series: Key Issues in Mental Health
Volume: 179
Published: 01 December 2014
10.1159/000365532
EISBN: 978-3-318-02604-7
...:762-767. 45. Argente J, Caballo N, Barrios V, Munoz MT, Pozo J, Chowen JA, Morande G, Hernandez M: Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa: effects of short- and long-term weight recuperation. J Clin Endocrinol...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 42
Published: 10 April 2014
10.1159/000358314
EISBN: 978-3-318-02639-9
... and the insulin receptor was one of the first hormone receptors to be detailed. These discoveries, paved with various Nobel Prizes, indicate that insulin is a prismatic hormone for endocrinology. Insulin is a very strong anabolic hormone with pleiotropic effects in multiple tissues. In contrast to many other...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 99
Published: 21 October 2013
10.1159/000353312
EISBN: 978-3-318-02481-4
... Abstract Angiogenesis is a constant hallmark of multiple myeloma progression and has prognostic potential. Multiple myeloma cells interact with surrounding host cells and extracellular matrix, this crosstalk affecting the most important aspects of the malignant phenotype, both at primary...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 74
Published: 18 July 2013
10.1159/000348391
EISBN: 978-3-318-02388-6
... estimates of how these factors operate in isolation and in synergy with each other. Ideally, LBW prevention should be cause specific in order to enhance the opportunity for effective action (see fig. 1 ). The implications of this model to LBW prevention - the topic of this paper - are multiple. Firstly...
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