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Book Chapter
Series: Contributions to Nephrology
Volume: 200
Published: 07 August 2023
10.1159/000529296
EISBN: 978-3-318-07124-5
... therapies, nonbiological extracorporeal liver support devices are the most widely used, mainly based on detoxification by eliminating accumulated toxins notably by adsorption on specific membranes and/or with plasmapheresis. One of the most recent techniques is the double plasma molecular adsorption system...
Book
Book
Book Cover Image
Series: Translational Research in Biomedicine
Volume: 8
Published: 10 May 2022
10.1159/isbn.978-3-318-07054-5
EISBN: 978-3-318-07054-5
Book
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
10.1159/000485717
EISBN: 978-3-318-06298-4
... of molecular hydrogen (H 2 ) on mesothelial cells from PDS in nonuremic rats. Summary: In the present study, we examined the effect of H 2 -containing PDS (commercially available neutral pH type) regarding the protection of peritoneal tissue in experimental chronic kidney disease rats. Furthermore, we...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 32
Published: 23 July 2018
10.1159/000469681
EISBN: 978-3-318-06063-8
... Abstract Multiple alterations in the expression levels of genes or proteins have been identified in gliomas, including activation of oncogenes and silencing of tumor suppressor genes. Illuminating these molecular mechanisms of tumorigenesis and treatment resistance is necessary...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 6
Published: 26 April 2018
10.1159/000485068
EISBN: 978-3-318-06313-4
.... Hatanaka K, Ito K, Shindo T, Kagaya Y, Ogata T, Eguchi K, Kurosawa R, Shimokawa H: Molecular mechanisms of the angiogenic effects of low-energy shock wave therapy: roles of mechanotransduction. Am J Physiol Cell Physiol 2016;311:C378-C385. 6. Lee FY, Zhen YY, Yuen CM, Fan R, Chen YT, Sheu JJ, Chen YL...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 31
Published: 06 February 2018
10.1159/000467378
EISBN: 978-3-318-06059-1
... with histologically identical tumors may have different outcomes and response to therapy. In recent years, extensive research has been done on three molecular markers in adult gliomas, namely MGMT promoter methylation, 1p/19q co-deletion, and IDH1 / IDH2 mutations. These markers may have either a prognostic...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 31
Published: 02 August 2017
10.1159/000470810
EISBN: 978-3-318-06051-5
... episode of psychosis and progressing long thereafter [ 1 , 2 ]. Herein, we will focus on the molecular basis of psychosis development and neuroprogression, first describing the N-methyl- D -aspartate receptor (NMDAR) model of psychosis, and then outlining the literature on the important roles...
Book Chapter
Series: Contributions to Nephrology
Volume: 189
Published: 22 December 2016
10.1159/000450781
EISBN: 978-3-318-05929-8
... Abstract Background: With the identification of β 2 -microglobulin (β 2 MG) as an active participant in dialysis-related amyloid fibril formation, low-molecular-weight proteins (LMWPs) are now recognized as a distinct class of uremic toxins, and numerous compounds in this category have been...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 46
Published: 23 May 2016
10.1159/000443871
EISBN: 978-3-318-05840-6
...-positive individuals). Thus, that study [ 42 ] provided the first demonstration of the strong genetic protection conferred by DRB1 * 0403 for AAD, similarly to what was observed in T1DM. The molecular mechanisms of HLA class II genetic predisposition are not yet fully understood. A hypothesis...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 78
Published: 19 April 2016
10.1159/000442121
EISBN: 978-3-318-05802-4
... Abstract The field of salivary gland tumor biology is quite broad, given the numerous subtypes of both benign and malignant tumors originating from the major and minor salivary glands. Knowledge about the molecular pathology of these lesions is still limited, and there are few clinically useful...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 45
Published: 21 March 2016
10.1159/000442276
EISBN: 978-3-318-02738-9
... body are poor in anatomical landmarks. This leads to problems in their interpretation. These may be overcome when registering the molecular maps of NIS expression pixel-wise to image datasets from imaging modalities better suited to visualizing morphology than radioiodine scanning, such as CT or MRI...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 45
Published: 21 March 2016
10.1159/000442317
EISBN: 978-3-318-02738-9
... Abstract The major workload in the field of adrenal imaging comprises patients with adrenal tumors incidentally depicted by imaging performed for other reasons than adrenal disease. These so-called ‘incidentalomas' are generally managed by CT and MRI, and molecular imaging techniques...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 45
Published: 21 March 2016
10.1159/000442329
EISBN: 978-3-318-02738-9
... diagnosis of or therapeutic purposes for pituitary lesions is very limited. Only in very specific cases might these molecular imaging techniques become helpful. These include the differential diagnosis of pituitary lesions, ectopic production of pituitary hormones, such as adrenocorticotrophic hormone...
Book Chapter
Series: Frontiers of Oral Biology
Volume: 18
Published: 01 December 2015
10.1159/000351895
EISBN: 978-3-318-05480-4
... such as prostaglandins, interleukins, chemokines, leukotrienes, growth factors, wnt signalling and bone morphogenetic proteins are involved in the regulation of bone remodeling. We discuss here cells and mediators involved in the cellular and molecular machanisms of bone resorption and bone formation. Cell Types...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 20
Published: 28 September 2015
10.1159/000382098
EISBN: 978-3-318-05497-2
... of NB-specific treatment options; however, due to the rapid development of drug resistance experienced in diseases with a similar pathogenesis, monotherapeutic approaches are limited. Multimodal therapies combining molecular-targeted drugs with low-dose chemotherapy, an optimized metronomic timing...
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 02 June 2015
10.1159/000375215
EISBN: 978-3-318-03004-4
... mutations) demonstrating sensitivity to gene dosage in either direction [ 29 ]. When the TBX20 gain-of-function mutation was coexpressed with NKX2.5 and GATA4/5, the transcriptional activity of TBX20 was synergistically increased demonstrating the common molecular pathway through which...
Book
Book Cover Image
Series: Karger eBooks Non-Series Collection
Published: 02 June 2015
10.1159/isbn.978-3-318-03004-4
EISBN: 978-3-318-03004-4