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Book Chapter
Series: Contributions to Nephrology
Volume: 195
Published: 22 May 2018
10.1159/000486930
EISBN: 978-3-318-06350-9
... Abstract Minimal change nephrotic syndrome (MCNS) usually responds to steroids but frequently relapses, requiring additional treatment with immunosuppressive agents. Rituximab is a chimeric murine/human monoclonal immunoglobulin G1 antibody that targets CD20, a B-cell differentiation marker. B...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 20
Published: 28 September 2015
10.1159/000382102
EISBN: 978-3-318-05497-2
... Abstract Detecting minimal amounts of tumor cells in bone marrow, peripheral blood, putative metastatic sites, lymph nodes or in other tissues, compartments or body fluids has become a major goal in cancer diagnostics. For neuroblastoma patients, the clinical relevance of minimal residual...
Book Chapter
Series: Progress in Respiratory Research
Volume: 39
Published: 31 August 2010
10.1159/000320830
EISBN: 978-3-8055-9567-4
... ). Topical (inhalation, intranasal) delivery may enable high levels of local PDE4 inhibition within the target tissue of the lung, and minimize systemic toxicity. Number of new chemical entity (NCE) patents claiming phosphodiesterase type 4 inhibition. Figure 1. Number of new chemical entity (NCE...
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Series: Advances in Biological Psychiatry
Volume: 1
Published: 07 August 1978
10.1159/000401866
EISBN: 978-3-318-03050-1