... Abstract Vigorous investigations for cerebral microbleeds (CMBs) have been made since the late 1990s. CMBs on paramagnetic-sensitive magnetic resonance sequences correspond pathologically to clusters of hemosiderin-laden macrophages and have emerged as an important new imaging marker...

...: Neuroimaging standards for research into small vessel disease and its contribution to aging and neurodegeneration. Lancet Neurol 2013;12:822-838. 3. Greenberg SM, Vernooij MW, Cordonnier C, Viswanathan A, Al-Shahi Salman R, Warach S, et al: Cerebral microbleeds: A guide to detection and interpretation...

...: Overviews of patients with chronic dialysis patients in Osaka, as of December 2016. J Osaka Society for Dialysis Therapy 2017;35:145-163. 5. Charidimou A, Kakar P, Fox Z, Werring DJ: Cerebral microbleeds and recurrent stroke risk: systematic review and meta-analysis of prospective ischemic stroke...

... hyperintensities (WMHs), and cerebral microbleeds (CMBs), is related to the future onset of stroke. Cerebral small-vessel disease is caused by microvascular damage to the small penetrating arteries of the middle cerebral artery including arteriolosclerosis, fibrinoid necrosis, and lipohyalinosis attributed...

..., Viswanathan A, Al-Shahi Salman R, Warach S, Launer LJ, Van Buchem MA, Breteler MM: Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009;8:165-174. 26. Viswanathan A, Chabriat H: Cerebral microhemorrhage. Stroke 2006;37:550-555. 27. Naganuma T, Takemoto Y, Yamasaki T, Shima...

... that asymptomatic cerebrovascular diseases, including silent cerebral infarction (SCI), white matter hyperintensities (WMHs), and cerebral microbleeds (CMBs), are related to future onset of stroke, cognitive impairment, and dementia. Magnetic resonance imaging studies have revealed a higher prevalence of SCI...

... function, auto-regulation, and relatively low-flow and high-oxygen-extraction systems [ 9 ]. Studies have demonstrated that retinal microvascular lesions are strongly correlated with cerebral small-vessel disease including white matter lesions and cerebral microbleeds [ 10 ]. Hence, retinal vascular...

.... 2013;8:1583–90. 16. Kaw D, Malhotra D. Platelet dysfunction and end-stage renal disease. Semin Dial. 2006;19:317–22. 17. Ovbiagele B, Wing JJ, Menon RS, Burgess RE, Gibbons MC, Sobotka I, et al. Association of chronic kidney disease with cerebral microbleeds in patients with primary intracerebral...

...: Proliferative retinopathy in type 1 diabetes is associated with cerebral microbleeds, which is part of generalized microangiopathy. Diabetes Care 2014;37:1165–1168. 22. Rodill LG, Exalto LG, Gilsanz P, Biessels GJ, Quesenberry CP, Whitmer RA: Diabetic retinopathy and dementia in type 1 diabetes. Alzheimer...

... JS: Moyamoya disease-related versus primary intracerebral hemorrhage: [corrected] location and outcomes are different. Stroke 2012;43:1947-1950. 86. Kikuta K, Takagi Y, Nozaki K, Sawamoto N, Fukuyama H, Hashimoto N: The presence of multiple microbleeds as a predictor of subsequent cerebral...

... brain microbleeds, as well as their number, has been associated with the occurrence of late seizures during long-term follow-up, which might suggest a link to the underlying vasculopathy (cerebral amyloid angiopathy) [ 28 ]. The risk of developing late seizures cannot be predicted by the occurrence...

... hypertension [ 15 ], a bleeding diathesis in uraemia [ 16 ], and the greater presence and number of cerebral microbleeds (CMB) in CKD, particularly in Black patients [ 17 ]. CKD has also been strongly associated with all types of subclinical cerebrovascular anatomical abnormalities including white matter...

... anterior choroidal artery branches may explain the high prevalence of intraventricular hemorrhages in MMD patients. In addition, gradient-echo, T2*-weighted, and susceptibility-weighted MRI has identified cerebral microbleeds in 28-46% of MMD patients [ 86 , 87 , 88 ]. Significant brain hypoperfusion...

.... PLoS One 2014;9:e115777. 68. Evans A, Demchuk A, Symons SP, Dowlatshahi D, Gladstone DJ, Zhang L, et al: The spot sign is more common in the absence of multiple prior microbleeds. Stroke 2010;41:2210-2217. 69. Rodriguez-Luna D, Dowlatshahi D, Aviv RI, Molina CA, Silva Y, Dzialowski I, et al...

... within 2 days, to exclude other secondary causes such as tumour, cavernoma or microbleed-associated hypertensive or cerebral amyloid angiopathy-related haemorrhage. If the MRI result is negative, urgent diagnostic CA should be considered, particularly in the case of younger patients or those...

... multifocal or diffuse white matter changes especially in the anterior temporal lobes, subcortical lacunar infarcts, dilated Virchow-Robin spaces, and microbleeds [ 216 ]. Since the involved vessels are mainly small arterioles, angiographic findings are usually negative. However, a patient with multifocal...

.... PLoS One 2014;9:e115777. 68. Evans A, Demchuk A, Symons SP, Dowlatshahi D, Gladstone DJ, Zhang L, et al: The spot sign is more common in the absence of multiple prior microbleeds. Stroke 2010;41:2210-2217. 69. Rodriguez-Luna D, Dowlatshahi D, Aviv RI, Molina CA, Silva Y, Dzialowski I, et al...