... Abstract Mesothelial cells are an integral part of the peritoneum and play an important role in maintaining its structure and functions. A number of studies have been performed to evaluate the ability of mesothelial cells to regenerate and transdifferentiate. Mesothelial cells are also involved...

... Abstract Repopulation of the mesothelial monolayer after focal exfoliation, havingthe monolayer in vivo and in situ exposed to dialysis solutions, has not been thoroughlyinvestigated. This study describes repopulation of a ‘doughnut’ like mesothelial ring exfoliatedfrom the anterior liver...

... S, Chan TM: Intrinsic cells: mesothelial cells-central players in regulating inflammation and resolution. Perit Dial Int 2009;29(suppl 2):S21-S27. 8. Mutsaers SE, Prele CM, Lansley SM, Herrick SE: The origin of regenerating mesothelium: a historical perspective. Int J Artif Organs 2007;30:484...

... have been observed in the mesothelial monolayer: apoptosis, anoikis, secondary necrosis, pure necrosis and mitotic catastrophe. Death of mesothelial cells exposed to glucose-enriched solutions derives mainly from a degree of oxidative insult leading to DNA damage, provoked by glucose itself and/or its...

... of molecular hydrogen (H 2 ) on mesothelial cells from PDS in nonuremic rats. Summary: In the present study, we examined the effect of H 2 -containing PDS (commercially available neutral pH type) regarding the protection of peritoneal tissue in experimental chronic kidney disease rats. Furthermore, we...

... in the peritoneum. The development of cell culture techniques made it possible to cultivate peritoneal mesothelial cells in vitro and expose them to conditions similar to those occurring in the dialyzed peritoneum. Such experiments quickly revealed an enormous potential of human peritoneal mesothelial cells...

... efficient, changes in the sub-mesothelial layer can result in progressiveincreases in solute transfer and ultrafiltration diminution. Years of exposure to dialysis solutionsresult in an epithelial-to-mesenchymal transition of mesothelial cells and the formationof an avascular layer of intersitial matrix...

... metabolism. Kidney Int 1996;49:525-533 4. Witowski J, Jörres A, Coles GA, Williams JD, Topley N: Superinduction of IL-6 synthesis in human peritoneal mesothelial cells is related to the induction and stabilization of IL-6 mRNA. Kidney Int 1996;50:1212-1223 5. Hurst SM, Wilkinson TS, McLoughlin RM...

... Abstract During chronic peritoneal dialysis (PD), the peritoneal membrane undergoes structural and functional alterations that, in some patients, may eventually lead to loss of function as the ‘dialysis membrane’. These alterations include loss of mesothelial cells, thickening...

... Abstract There is now abundant evidence in both animal and human studies that sterile dialysissolutions result in the alteration of the peritoneal barrier. Mesothelial cells undergo an epithelialto-mesenchymal transition after less than 1 year of dialysis. After more than 6 years...

... pancreatic adenocarcinoma. Besides these, mesothelial cells and hepatocytes and bile duct cells from the liver may be sampled as well. Here, the cytological features of normal components and contaminants are described in detail. Normal Anatomy The pancreas is a retroperitoneal organ that is located...

... from metastatic non-small-cell carcinoma. Furthermore, granulomatous inflammation can be seen in the setting of malignancy, particularly with certain lymphomas, seminoma, and squamous cell carcinoma. 4. Mesothelial cells can also be seen in transbronchial biopsies and can be a diagnostic dilemma...

... in children on automated peritoneal dialysis. Pediatr Nephrol 2005;20:683-685 16. Gotloib L, Wajsbrot V, Shostak A: Osmotic agents hamper mesothelial repopulation as seen in the doughnut in vivo model. Perit Dial Int 2005;25:(suppl 3)S26-S30 17. Bender TO, Witowski J, Aufricht C, Endemann M, Frei U...

... and the glutathione precursor L-2-oxothiazolidine-4-carboxylic (OTZ), both showing antioxidant capabilities, are also promising agents that deserve to be further explored. Acute osmotic stress provokes different modes of cell death. In the long-term mesothelial cells adapt to the hypertonic environment, at least from...