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Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
10.1159/000506566
EISBN: 978-3-318-06734-7
... Abstract Josef von Mering discovered the glucosuric effect of phlorizin. Phlorizin is the progenitor of contemporary SGLT2 inhibitors. Von Mering also described the blood glucose-lowering effect of phlorizin and postulated that the action of phlorizin occurs in the kidney – a hypothesis which...
Book Chapter
Book
Series: Bibliotheca Paediatrica
Volume: 48
Published: 30 November 1948
Book Chapter
Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
EISBN: 978-3-318-06734-7
...-mering.de: Familiengeschichte. http://von-mering.de/index.php?option=com_content&view=article&id=130&Itemid=16 8. Von Mering FE: Geschichte der Burgen, Rittergüter, Abteien und Klöster in den Rheinlanden und den Provinzen Jülich, Cleve, Berg und Westfalen. Cologne, Heberle, 12 vol, 1833–1861...
Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
10.1159/000506549
EISBN: 978-3-318-06734-7
... colleague Freiherr Josef von Mering was the highlight of the first world congress of physiology in 1889. Minkowski was born 1858 in the Lithuanian city of Kaunas. His family immigrated to Königsberg in Prussia, where he studied medicine. Prof. Bernhard Naunyn became supervisor of his thesis and Minkowski...
Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
EISBN: 978-3-318-06734-7
... mellitus. Naunyn-Schmiedebergs Arch1884;18:35–55. 4. Minkowski O: Untersuchungen über den Einfluss der Leberexstirpation auf den Stoffwechsel.Naunyn-Schmiedebergs Arch 1886;21:41–88. 5. Von Mering J: Über künstlichen Diabetes. Centralbl Med Wissensch 1886;22:31–33. 6. Houssay BA: The discovery...
Book Chapter
Series: Aesthetic Dermatology
Volume: 5
Published: 09 February 2021
10.1159/000491854
EISBN: 978-3-318-06690-6
... Abstract Cosmeceuticals, those cosmetics with pharmaceutical-like effects, have taken over the prescriptions of dermatologists around the world, and even over the personal care industry. That fine line between mere cosmetics and drugs needs to be better understood. We think they should be used...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 85
Published: 18 December 2020
10.1159/000456686
EISBN: 978-3-318-06628-9
... thyroplasty does not increase the “bulk” of the atrophic vocal fold but merely brings the fold closer to its unaffected partner. Besides the obvious lateralization, there is occasionally a third dimensional component to the affected fold. The slipping and prolapse forward of the arytenoid cartilage due...
Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
10.1159/000506554
EISBN: 978-3-318-06734-7
..., Apollinaire Bouchardat suggested the suppression of bread and almost all other carbohydrates from the diet but conceded their partial reintroduction after the disappearance of glycosuria, which the patients could detect by tasting their own urine, a first in self-management! Finally, in 1889, von Mering...
Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
10.1159/000506563
EISBN: 978-3-318-06734-7
..., that important “discoveries” were made by obscure others way before bold announcements or, alternatively, that not much had been discovered after all. For example, the ketogenic effects of the plant extract phlorizin, later transformed into modern SGLT inhibitors, was described by von Mering in 1887, before...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490302
EISBN: 978-3-318-06341-7
... underlie the pathogenesis of noncommunicable diseases or are merely end results thereof, confronting the question of causality. This uncertainty notwithstanding, the complex and bidirectional interrelationship of the diet and the gut microbiota is becoming evident. Early exposures by the enteral route...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 6
Published: 26 April 2018
10.1159/000485050
EISBN: 978-3-318-06313-4
... of the clinical utility of medical shockwaves could elevate the management of multiple pathologies from being merely palliative, toward a more sanative approach, improving the quality of life of patients across their lifespan, while reducing the burden of healthcare costs globally. Introduction The theory...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 39
Published: 03 August 2016
10.1159/000445412
EISBN: 978-3-318-05865-9
... Abstract Background: Statistical methods are often considered as mere tools to address research questions. The lack of critical understanding can make their use sometimes highly questionable if not inappropriate. Biostatistics should be seen more as a paradigm than a set of tools. Knowledge...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 38
Published: 04 April 2016
10.1159/000442682
EISBN: 978-3-318-05606-8
... for unethical experimentation to discover the cause of multiple sclerosis or to try to induce epileptic convulsions in a hypoxic state. Some merely used neuropathological material from murdered patients for publications in scientific journals. In the totalitarian state, research funding and academic advancement...
Book Chapter
Series: Key Issues in Mental Health
Volume: 181
Published: 15 January 2016
10.1159/000440913
EISBN: 978-3-318-05621-1
... underlying mental disorder or a merely transient phenomenon. Five groups of symptoms and clinical features that are frequently reported by individuals with suspected psychosis risk states, yet share strong commonalities with other mental disorders and conditions and thus can be conceptualized as being part...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 30
Published: 28 September 2015
10.1159/000435938
EISBN: 978-3-318-05574-0
... afferent nociceptive input to the brain. The underlying mechanisms of the various emotional and cognitive modulatory influences may partly overlap, but also have some unique aspects. What becomes clear is that pain is not merely a reflection of the nociceptive input, but should be considered as a complex...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 41
Published: 22 July 2015
10.1159/000381162
EISBN: 978-3-318-05457-6
... of the microbiome advances, it is evident that these microbial populations participate in a multitude of symbiotic associations with us. The disruption of these associations can lead to a range of diseases beyond mere pathogenesis as microbial nutrition, signaling, and immune defense break down. It is known...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 34
Published: 09 July 2015
10.1159/000381411
EISBN: 978-3-318-05474-3
... TNF in vitro. However, mere neutralization of soluble TNF cannot be the only therapeutic modality of therapeutically efficient anti-TNF agents, as accumulating evidence indicates that effector cells expressing membrane-bound TNF are critically involved in the induction and perpetuation of chronic...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 79
Published: 10 September 2014
10.1159/000360720
EISBN: 978-3-318-02670-2
... Abstract Inflammatory bowel diseases (IBD) are chronic progressive diseases. Current therapeutic strategies have not significantly altered the natural history of IBD. In the wake of other chronic diseases, such as rheumatoid arthritis, the goal of therapy has now shifted from mere control...