... are treated with systemic chemotherapy either as an initial or salvage therapy, the overall benefits of chemotherapeutic agents remain modest, suggesting a median increase of survival in the range of 2 months [ 1 ]. The Role of Radiosurgery Stereotactic radiosurgery (SRS) has been used as salvage...

... in adult as well as pediatric patients. For adults, the median radiosurgery target volume was 4.7 cm 3 (range 0.6–33.7) and the median margin dose was 13.3 Gy (range 10–20) [ 2 ]. The overall survival (OS) after SRS for the entire series was 100, 88.9, and 88.9% at 1, 3, and 5 years, respectively...

... with WBRT, and 15 with SRS (Table 1 ). The median overall survival (OS) for the whole cohort was 33 months. There was no significant difference in OS between the WBRT and erlotinib groups (median 35 vs. 26 months, p = 0.62), whereas patients treated with SRS had a longer OS than those in the erlotinib...

... gliomas are the most common primary brain tumors and are associated with very low survival rates. Of these neoplasms, glioblastoma multiforme (GBM), corresponding to World Health Organization (WHO) histopathological grade IV, is the most common and has a dismal prognosis with a median survival of only 14...

...%) and parafalcine (41%) meningiomas treated with a median prescription dose of 15 Gy showed 3- and 5-year tumour control rates of 85 and 70%, respectively [ 12 ]. The authors hypothesised that these lower control rates relative to other locations may be due to longer dural tails leading to higher recurrence rates...