... failure patients. With the use of mechanical, chemical, or biological devices, it is possible to temporarily and partially replace or assist the liver function [ 6 ]. ALSS consist of bioartificial liver support systems and non-bioartificial liver support systems (NBALSS). Bioartificial liver support...

... during sweating in mice (C57BL6/J). Since it was difficult to investigate the mechanism of AQP5 translocation in human tissues, we used mouse tissues for this investigation. Whether the mice were sweating or not through their paws was determined using a modified Minor method; mouse paws were painted...

... mechanisms could influence the functional decline or the malignant transformation of HSCs during aging. (a) The maintenance of HSC quiescence: low cell cycle activity is a characteristic sign of HSCs, and this may prevent the accumulation of replication-induced DNA damage and epigenetic alteration of the DNA...

... 1 Contribution of different salivary glands to the volume of whole-mouth saliva (WMS) Reflex Secretion of Saliva Afferent Mechanisms Secretion from the major salivary glands is evoked by interaction of tastants with different receptors on taste buds located predominantly...

... interaction with its host. The range of interactions between host and microorganism are widely recognized to have both positive and negative consequences for the host, but rarely are these interactions considered to have as a common mechanism a shared use and recognition of neuroendocrine hormones...

... Abstract Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor. Viruses that are associated with malignant transformation have evolved unique mechanisms to interfere with this interaction to evade antiviral T cell responses. EBV exploits many immune evasive strategies...

... Abstract Objective: The purpose of this review is to outline the mechanism of action of a novel ocular lubricant incorporating hydroxypropyl-guar (HPG) and the demulcents polyethylene glycol 400 and propylene glycol. Methods: The literature relating to the mechanism of action of Systane...

... of angiogenesis, and suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity as anticarcinogenesis mechanisms of tocotrienols both in vivo and in vitro. Extension of the duration of host survival was observed in tumor-implanted mice treated with tocotrienol. Tocotrienols induce apoptosis...

... options. This review describesthe organization of the HCV genome and biological systems useful to examine viral replication. Two viralenzymes, the NS3/4A serine protease and the NS5B RNA-dependent RNA polymerase, have been thesubject of intensive efforts to find small-molecule, mechanism-based inhibitors...

... Abstract The mode of action of intravenous immunoglobulin (IVIg) is complex. An ongoingresearch continues to elaborate and identify novel mechanisms. Recent advances have demonstratedthat IVIg has direct effect on keratinocytes, the target cells of autoimmune blisteringdiseases. IVIg protects...

... effects of glucose drive at least some aspects of the aging process and, conversely,that protective effects of dietary restriction are mediated by a reduction in exposureto glucose. The mechanisms mediating cumulative toxic effects of glucose are suggested bytwo general principles of metabolic processes...

... Abstract Alcoholic beverage consumption is classified as a known human carcinogen, causallyrelated to an increased risk of cancer of the upper aerodigestive tract. The formation ofacetaldehyde from ethanol metabolism appears to be the major mechanism underlying thiseffect. Acetaldehyde has been...