...) and intrathecal Borrelia burgdorferi -specific antibody production. As the clinical picture of LNB may be unspecific, a lumbar puncture to analyze the CSF is usually mandatory for confirmation of the suspected diagnosis. The indications for a lumbar puncture and the limitations of the different diagnostic...

... Abstract Lumbar fusion is a commonly performed procedure for the treatment of painful instabilityof the spine, usually manifest as chronic low back pain. The safety, efficacy, and cost ofthese procedures have been questioned in the professional and lay press. Recently, evidencebased medicine...

... Rheum Dis 2004;63:71-77. 12. Tilkeridis C, Bei T, Garantziotis S, Stratakis CA: Association of a COL1A1 polymorphism with lumbar disc disease in young military recruits. J Med Genet 2005;42:e44. 13. Jin H, van't Hof RJ, Albagha OME, Ralston SH: Promoter and intron 1 polymorphisms of COL1A1...

... concentrated on survivors of acute lymphoblastic leukaemia (ALL). There is now good evidence that earlier treatment protocols that included cranial irradiation with doses of 24 Gy or greater may result in growth hormone deficiency and low bone mineral density (BMD) in the lumbar spine and femoral neck. Under...

... ] and lumbar disc disease (LDD) [ 12 ]. Recently, a second functional COL1A1 promoter polymorphism (-1997 G/T; rs1107946) was investigated with the risk of ACL ruptures in professional soccer players [ 8 ]. The -1997 G/T variant is in linkage disequilibrium with the Sp1 polymorphism (+1245 G/T), and together...

... Abstract Neuromodulation practitioners increasingly recognize the potential for peripheral nerve field stimulation (PNfS) to treat pain originating from the trunk. Conditions resulting in truncal pain that may respond to PNfS include cervical and lumbar postlaminectomy syndrome, inguinal...

... the trigeminal nerve roots and synapse on the second-order neurons in an area that extends from the lower brainstem to the C1 and C2 levels of the spinal cord. The risks of cervical puncture may explain the rarity of its use. However, new devices allowing a simpler lumbar approach and the ongoing opioid crisis...

... V, Feler C, Naumann C: Lumbar and sacral nerve root stimulation (NRS) in the treatment of chronic pain: a novel anatomic approach and neuro stimulation technique. Neuromodulation 1999;2:23-31. 17. Oakley JC: Spinal cord stimulation in axial low back pain: solving the dilemma. Pain Med 2006;7:S58...

... radiculopathy involving the lower extremities, we developed a hybrid technique of SCS and PNS that offers potential control of both axial pain in the lumbar area and radicular pain to the lower extremities. This chapter presents our results and the possible mechanisms of action. The management...