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ltration

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Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107247
EISBN: 978-3-318-01494-5
... Abstract Push/pull hemodiafi ltration is characterized by alternate fi ltration and backfi ltration,while sterile pyrogen-free dialysate is fl owing through a hemodiafi lter. During the fi ltrationphase, uremic substances are eliminated not only by diffusive, but also by convective...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107233
EISBN: 978-3-318-01494-5
... contactbetween fi bers) or the moiré structure (waved shape of fi bers to prevent contact betweenadjacent fi bers). Furthermore, the process of transmembrane crossfi ltration along the lengthof the dialyzer can be very different in quantity and direction, thus interfering signifi cantlywith the diffusion process...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107248
EISBN: 978-3-318-01494-5
... Abstract It has recently been suggested that the potentials of modern high-fl ux membranes couldbe exploited with the so-called internal hemodiafi ltration (iHDF) technique. In principle,iHDF works just as high-fl ux hemodialysis but requires the convective dose to be clinicallyrelevant...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107254
EISBN: 978-3-318-01494-5
... Abstract Hemodiafi ltration with larger amounts of substitution fl uid offers an optimal way toremove uremic substances. Hemodiafi ltration could be indicated for all hemodialysis patients.Large observational studies have shown an association of a lower mortality risk with hemodiafiltration...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107238
EISBN: 978-3-318-01494-5
... Abstract The objective of hemodiafi ltration (HDF) is to increase the convective transport of solutespoorly removed by diffusion, and therefore ultrafi ltration (UF) beyond the desired weightloss is prescribed. The excess UF is compensated for by infusion of a physiological solutionwhich should...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107242
EISBN: 978-3-318-01494-5
... Abstract Mixed-dilution hemodiafi ltration (mixed HDF) controlled by the transmembrane pressure(TMP) feedback, improves the depurative capacity of the more traditional HDF techniquesby fully exploiting the convective mechanism of small- and middle-molecular-weightsolute removal. The feedback...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107246
EISBN: 978-3-318-01494-5
... Abstract Hemodiafi ltration (HDF) can augment the effi ciency of removal of small and large solutesfor renal replacement therapy. Double high-fl ux HDF was developed in 1984 with theobjective to shorten treatment time compared to conventional therapy. It consists of a serialpair of dialyzers...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107250
EISBN: 978-3-318-01494-5
... Abstract The biologic response to uremia and to the associated chronic infl ammation is an activearea of research. Among the different modalities developed in the technology fi eld of chronicrenal replacement, hemodialfi ltration has evolved consistently. On-line production of substitutionfl...
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/isbn.978-3-318-01494-5
EISBN: 978-3-318-01494-5
Book Chapter
Series: Contributions to Nephrology
Volume: 163
Published: 15 June 2009
10.1159/000223775
EISBN: 978-3-8055-9203-1
... Abstract The rate of transport of small solutes across the peritoneal membrane is one of the most important measurements in PD patients. Signifi cant between-patient variability is associated with an impact on small solute clearance, ultrafi ltration and even survival. Cross-sectional...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107230
EISBN: 978-3-318-01494-5
... Abstract The evolution of hemodiafi ltration (HDF) has become possible by the advances in theconstruction of dialysis membranes. The availability of a high-fl ux membrane, partiallyhydrophilic with high sieving coeffi cients and a reduced wall thickness has made it possibleto conveniently...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107234
EISBN: 978-3-318-01494-5
... Abstract Background: Prescribing therapeutic conditions for online predilution hemodiafi ltration(HDF) with fi xed total dialysate fl ow rate QDtotal is not straightforward, since the increasein the substitution fl ow rate QS is compensated by the decrease in the net dialysate fl ow rateQDnet...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107236
EISBN: 978-3-318-01494-5
... Abstract The chapter describes and analyzes the most commonly used systems for online substitutionfl uid production in hemofi ltration and hemodiafi ltration, covering in detail systemscomprising 2 multiuse fi lters, or 2 multiuse fi lters in combination with 1 disposable fi lter. Agenerally...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107239
EISBN: 978-3-318-01494-5
... Abstract Hemodiafi ltration (HDF) is well known to increase the solute convective clearance dueto increased ultrafi ltration but requires substantial amounts of high-quality reinfusion fl uid.Initially in the early 90s, individual bags or containers of reinfusion fl uid were used and causedmany...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107241
EISBN: 978-3-318-01494-5
... Abstract Online production of substitution fl uid by ‘cold sterilization’ (ultrafi ltration) of dialysisfl uid gives access to virtually unlimited amounts of sterile and nonpyrogenic solution. Theincorporation of the online hemodiafi ltration (ol-HDF) module into the dialysis...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107244
EISBN: 978-3-318-01494-5
... Abstract Acetate-free biofi ltration (AFB) is a hemodiafi ltration technique that, technically aswell as biologically speaking, has all the premises for being a perfectly biocompatible techniquecapable of satisfying even the demands of critical patients laden with comorbidities.Important...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107251
EISBN: 978-3-318-01494-5
... these middle molecules. These solutes are not well cleared by low-fl ux dialysis.High-fl ux dialysis will clear middle molecules, partly by internal fi ltration. This convectivecomponent of high-fl ux dialysis can be enhanced in a predictable way by haemodiafi ltration(HDF). The convective and diffusive...
Book Chapter
Series: Contributions to Nephrology
Volume: 163
Published: 15 June 2009
10.1159/000223773
EISBN: 978-3-8055-9203-1
... by inflammation or ischemia. Ultrafi ltration failure occurs when intraperitoneal pressure is too high, the inflamed peritoneum dissipates the osmotic agent rapidly because of hyperpermeable angiogenic vessels, or peritoneal scarring lowers the osmotic pressure near the blood supply and there is no force...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107235
EISBN: 978-3-318-01494-5
... Abstract Online haemodiafi ltration is an extracorporeal technique, utilizing highly permeableand highly biocompatible membranes, which permits the combination of convective and diffusivesolute removal from the blood and offers increased removal of medium-weight uraemicsolutes, compared...
Book Chapter
Series: Contributions to Nephrology
Volume: 158
Published: 16 August 2007
10.1159/000107237
EISBN: 978-3-318-01494-5
... Abstract Great improvements in water treatment technology and the spread of ultrafi ltration forcold sterilization have been the basic support for the development and diffusion of on-linedialysis treatments. Some 20 years ago, nephrologists recognized that the offi cial standardsfor dialysis fl...