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Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444568
EISBN: 978-3-318-05856-7
... Abstract There has been considerable progress in identifying the mutations primarily associated with congenital hearing loss caused by a single gene. The next challenge is the discovery of genes and mutations associated with common acquired hearing loss in the human population such as age...
Book Chapter
Book Chapter
Book Chapter
Series: Frontiers of Hormone Research
Volume: 54
Published: 17 December 2021
10.1159/000514692
EISBN: 978-3-318-06791-0
... Abstract Cancer therapy-induced bone loss (CTIBL), occurring especially in hormone-treated breast and prostate cancer patients, is a noteworthy long-term consequence of cancer treatments. Because of its negative impact on the quality life of cancer survivors, it deserves much attention. We here...
Book Chapter
Series: Aesthetic Dermatology
Volume: 5
Published: 09 February 2021
10.1159/000491851
EISBN: 978-3-318-06690-6
... around improvement in skin elasticity and anecdotal evidence regarding benefits for rosacea, but further studies on its effects on hair have yet to be conducted [ 16 , 17 ]. While the appearance of hair is one target of cosmetics and cosmeceuticals, treatment and prevention of hair loss is another...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 52
Published: 05 February 2019
10.1159/000493237
EISBN: 978-3-318-06383-7
... and found a strong association between the odds of osteoporosis by bone density and hyponatremia. This study pointed out that age-dependent decline in bone density may mask hyponatremia-induced bone loss. Multiple independent retrospective studies, epidemiological studies, and prospective clinical studies...
Book Chapter
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444561
EISBN: 978-3-318-05856-7
... Abstract Relationships are central to social well-being and emotional resilience across the lifespan, and good hearing and communication is integral to their establishment and maintenance. However, hearing loss is one of the most prevalent chronic conditions of ageing and significantly affects...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444564
EISBN: 978-3-318-05856-7
... the diagnostic evaluation of patients with hearing loss, considering the audiological, radiological and clinical aspects. Background Communicatively significant permanent hearing loss affects up to 1-3:1,000 newborns, with 50-60% of cases estimated to result from genetic etiologies [ 1 ]. Infectious...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444599
EISBN: 978-3-318-05856-7
... Abstract Hereditary hearing loss is a classic genetically heterogeneous condition with nearly 100 nonsyndromic hearing loss genes currently described and many more awaiting discovery. Priorities in the field with potentially rapid clinical application are the identification of all genes...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444566
EISBN: 978-3-318-05856-7
... Abstract Hearing loss is a common neurosensory disorder. Mutations of many genes are associated with hearing loss, and there are a great variety of reasons for phenotypic variability, including environmental causes such as loud noise and exposure to ototoxic drugs. Additionally...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444565
EISBN: 978-3-318-05856-7
... Abstract Age-related hearing loss (ARHL) is a complex multifactorial disease. It is highly prevalent in older adults and has significant adverse impact on communication, mental health and quality of life. Severity and onset of ARHL varies substantially between individuals, and heritability...
Book Chapter
Series: Current Problems in Dermatology
Volume: 47
Published: 26 February 2015
10.1159/000369398
EISBN: 978-3-318-02775-4
.... Family History It is important to ask the patient whether someone else in her/his family suffers from hair problems. A positive family history is typical of male and female pattern hair loss (androgenetic alopecia) and is often found in alopecia areata [ 1 ], where it is considered a negative...
Book Chapter
Series: Current Problems in Dermatology
Volume: 47
Published: 26 February 2015
10.1159/000369404
EISBN: 978-3-318-02775-4
... Abstract Female pattern hair loss, or female pattern androgenetic alopecia, is a nonscarring alopecia with a multi-factorial etiology that mostly affects postmenopausal women and is characterized by a reduction in hair density over the crown and frontal scalp. The clinical picture...
Book Chapter
Series: Current Problems in Dermatology
Volume: 47
Published: 26 February 2015
10.1159/000369405
EISBN: 978-3-318-02775-4
... Abstract Hair diseases represent frequent complaints in dermatology clinics, and they can be caused by a number of conditions reflected by specific diagnoses. Hair loss is not uncommon in the pediatric group, but its patterns in this group are different from those seen in adults. Additionally...
Book Chapter
Series: Current Problems in Dermatology
Volume: 47
Published: 26 February 2015
10.1159/000369413
EISBN: 978-3-318-02775-4
... Abstract Humans are social animals that communicate disproportionately via potent genetic signals imbued in the skin and hair, including racial, ethnic, health, gender, and age status. For the vast majority of us, age-related hair pigment loss becomes the inescapable signal of our disappearing...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 19
Published: 27 January 2015
10.1159/000368136
EISBN: 978-3-318-02799-0
... of pediatric obesity, it can be discouraging that there is no single proven strategy for success in pediatric weight management. It is problematic even to define success , although most researchers, clinicians, funding agencies, government officials, and families would view weight loss as the most meaningful...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 39
Published: 16 May 2014
10.1159/000358903
EISBN: 978-3-318-02653-5
... that several receptor-mediated functions decline with age because either of the loss of receptors or their uncoupling from their specific signalling pathways. The mechanisms and biological as well as pathological consequences of this age-dependent receptor loss and signal transduction changes are described...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 75
Published: 15 August 2013
10.1159/000345818
EISBN: 978-3-318-02333-6
... response. Excessive anti-inflammatory measures may impair recovery. Many injuries result in limb immobilization. Immobilization results in muscle loss due to increased periods of negative muscle protein balance from decreased basal muscle protein synthesis and resistance to anabolic stimuli, including...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 73
Published: 26 October 2012
10.1159/000341282
EISBN: 978-3-318-02116-5
..., and the tendency for weight-reduced individuals to regain weight to levels of fat stores similar to those present prior to initial weight loss. Brain responses to food and the observed changes in energy expenditure that occur during maintenance of a reduced weight are largely reversed by the administration...