Search Results for long

... Abstract SummaryLong-term administration of vindesine, included in a maintenance regimen for acute lymphoblastic leukemia (ALL) with poor prognosis, proved to be effective. There was no apparent long-term cumulative neurotoxicity. ...

... was consistent (predominantly in the jejunum, impaired by biliary content), but it wasn’t until a few years ago that an oral formulation began to take its space in clinical practice. In the late ‘90s, a long-acting-release formulation of Octreotide ( Octreotide LAR ) was launched. It exploited a polymer...

... Abstract Infants born very preterm miss out on the in utero transfer of the omega-3 and omega-6 long-chain polyunsaturated fatty acids that occurs during the third trimester. A number of studies have explored the impact of increasing the enteral intakes of omega-3 +/– omega-6 long-chain...

... suffer from perinatal malnutrition. Stress and malnutrition can act closely aligned and stress and nutrition interact. There is emerging evidence that specific nutritional supplementation during various time windows may ameliorate the long-lasting effects of early-life stress, although possible...

... Metabolic programming of long-term health Developmental origins of adult health and disease Breastfeeding and obesity Long-term impact of infant feeding Non-communicable disease risk Key Messages Environmental cues, including nutritional and metabolic exposures during sensitive...

... dysfunction, metabolic syndrome, and low bone mineral density. Long-term follow-up (LTFU) care, including education, risk-based prevention, and surveillance strategies, is essential to reduce the burden of endocrine complications and to allow for timely interventions. To integrate scientific expert knowledge...

... growth and development. Current nutrition recommendations are largely based on limited evidence, especially regarding long-term outcomes. Rather than aiming for a specific weight gain or body composition for preterm infants, a better goal would be to support preterm infants to grow at rates similar...

... Abstract Long-term type 1 neovascularization (NV) evolution shows different outcomes: stabilization, chronicity, fibrosis, atrophy, hemorrhages, or retinal pigment epithelium (RPE) tears. We do not know the reason why some NVs become stable, bringing to a standstill its evolution and activity...

.... The papyrus, a 20-m long, 30-cm wide roll, contains information on more than 700 recipes and 400 medicinal preparations for the treatment of stomach, heart, eye, skin, tooth diseases and numerous other conditions, including some mental disorders such as dementia and depression. Prescriptions include all...

... Abstract The neonatal immune system has its own reactivity, constraints, and challenges, which profoundly differ from the adult. Breast milk is most probably a key requirement both for optimal immune function in early life and for imprinting of the immune system for long-term immune health...

... Abstract Many adults born very preterm are healthy and well. However, very preterm birth may be regarded as a “chronic condition” with a higher risk of long-term morbidities that warrant attention or follow-up in adult life, and the degree of maturity at birth should be routinely assessed...

... Abstract Maternal diabetes in pregnancy has short-term as well as long-term implications for the offspring. Observational studies in humans and animals as well as interventional studies in animals have found associations between fetal exposure to intrauterine hyperglycemia and later development...

... screening for hyperglycemia is recommended in women with previous GDM, but the cost – benefit of this is not fully known. A healthy lifestyle is generally recommended, based on common sense and a few long-term intervention studies. Introduction Gestational diabetes is characterized by impaired...

...- and long-term adverse radiation effects (ARE). Nidus obliteration typically occurs between 1 and 5 years after GKRS. The most important factor associated with nidus obliteration is the prescribed radiation dose. The chance of obliteration ranges from 60 to 70% for margin doses of 15–16 Gy to 90% or more...

..., it has also been reported that intractable pain in long-term HD patients, including DRA-related symptoms, not only decreases quality of life but also is also associated with a higher risk of hospitalization and death [ 20 ]. Therefore, the selection of a dialysis modality or combination therapy...

... Abstract It is well established that nutrition during the first 1,000 days of life can have a long-term effect on growth, metabolic outcome, and long-term health. We review the long-term anthropometric follow-ups of children with risk of later morbidity: (a) very-low-birth-weight (VLBW) infants...

... Abstract The disk of hyaline cartilage that is interposed between the epiphysis and the metaphysis of each of the long bones is responsible for its elongation, and, thus, when the lower limbs are concerned, for increases in bodily height. This so-called growth plate is avascular, aneural...