... into flat two-dimensional coloured planes, and distorted conventional perspective with often gross brushstrokes intentionally giving an “unfinished” aspect to the work. It is little known that Manet had a very painful second part of his life, due to excruciating limb and chest pains, which developed...

... and that 25% of such DFUs will eventually result in major limb amputation. A recent report documented that at least in the United States, the annual direct costs of diabetic limb complications exceeded those of each of the 5 most common forms of cancer [ 3 ]. The primary risk factors for DFU and amputation...

... Abstract The thick ascending limb of the loop of Henle reabsorbs 20–30% of filtered sodium chloride (NaCl) and generates the osmotic gradient necessary for water absorption in the distal nephron. It is second only to the collecting duct as a source of renal endothelin (ET)-1, which inhibits...