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lacrimal

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Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315019
EISBN: 978-3-8055-9419-6
... Abstract Aqueous tear deficiency due to lacrimal gland insufficiency is one of the major causes of dry eye. In severe cases, such as Sjoegren’s syndrome, Stevens-Johnson syndrome or ocular cicatricial pemphigoid, therapy with artificial tears can be insufficient to relieve severe discomfort...
Book Chapter
Series: Developments in Ophthalmology
Volume: 41
Published: 23 May 2008
10.1159/000131085
EISBN: 978-3-8055-8377-0
... the problem of impaired production, this leading to significant concentration ofinflammatory mediators on the abnormal ocular surface - this concentration being even greaterwhere tear drainage is impaired. Nasolacrimal duct obstruction is, moreover, associated with abackwash of toxic debris from the lacrimal...
Book Chapter
Series: Developments in Ophthalmology
Volume: 41
Published: 23 May 2008
10.1159/000131090
EISBN: 978-3-8055-8377-0
... Abstract Background: Next to medical therapy, blockage of the lacrimal drainage system is thecommonest form of treating dry eye. Rather than applying an artificial tear, the latter helps topreserve any remaining natural tear fluid, which by far has the best wetting and nutrient capacityfor...
Book Chapter
Series: Developments in Ophthalmology
Volume: 41
Published: 23 May 2008
10.1159/000131091
EISBN: 978-3-8055-8377-0
... Abstract Background: If a lacrimal plug that successfully improves dry eye symptoms is spontaneouslylost or causes unwanted effects other than epiphora, surgical occlusion of the lacrimaldrainage system should be considered. Here we review current irreversible and reversible techniquesto...
Book Chapter
Series: Developments in Ophthalmology
Volume: 30
Published: 01 October 1999
10.1159/000060750
EISBN: 978-3-318-00425-0
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Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 21 August 2017
10.1159/000475960
EISBN: 978-3-318-06085-0
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 21 August 2017
10.1159/000475961
EISBN: 978-3-318-06085-0
... connected with drying of the ocular surface. In the course of active GO, ocular surface damage correlated significantly with a reduced tear secretion due to autoimmune lacrimal gland impairment, but not with increased ocular surface or impaired upgaze [ 8 ]. Other studies had shown that in patients...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315017
EISBN: 978-3-8055-9419-6
... (conjunctiva and cornea) is anatomically continuous with its mucosal adnexa (the lacrimal gland and lacrimal drainage system) and contains a mucosal immune system termed ‘eye-associated lymphoid tissue’ (EALT). This extends from the periacinar lacrimal-gland-associated lymphoid tissue along the excretory ducts...
Book Chapter
Series: Developments in Ophthalmology
Volume: 41
Published: 23 May 2008
10.1159/000131066
EISBN: 978-3-8055-8377-0
... Abstract Purpose: To survey briefly current knowledge on the normal preocular tear film.Methods: Sections deal with: (1) Formation of the film, its physical dimensions and ratesof inflow and outflow of tears, and briefly the pathways of nervous control of tear productionin the main lacrimal...
Book Chapter
Series: Developments in Ophthalmology
Volume: 41
Published: 23 May 2008
10.1159/000131068
EISBN: 978-3-8055-8377-0
...) anatomy of the ocular surface, lacrimal gland, eyelid and nasolacrimalducts. (2) The meaning and importance of the lacrimal functional unit and the function of themucosal innate immune system are briefly summarized. (3) Finally, the occurrence and the possiblefunction of EALT is discussed with regard...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 92
Published: 24 January 2007
10.1159/000099268
EISBN: 978-3-318-01404-4
... Abstract Over the past 20 years it has become clear that dry eye syndrome (DES) or keratoconjunctivitissicca (KCS) is a complex multifactorial disease characterized by an immune andinflammatory process that affects the lacrimal glands and ocular surface. In this paradigm,inflammation is seen...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315023
EISBN: 978-3-8055-9419-6
... of pathophysiological mechanisms involved [ 2 , 5 , 19 , 20 ]. Live animal models, which are used to examine quantitative tear film deficiency and environmental stress, use surgical removal, irradiation or closure of the lacrimal gland excretory duct [ 21 – 23 ], prevention of eyelid closure [ 24 ], drug-induced...
Book Chapter
Series: ESASO Course Series
Volume: 5
Published: 25 August 2014
10.1159/000363716
EISBN: 978-3-318-02606-1
... confirmed by orbital biopsy. The main orbital tumour categories include lymphoma, vascular tumours, epithelial lacrimal gland tumours, neural tumours and metastases. Cavernous haemangioma is the most common benign orbital tumour in adults and can be seen as a well-circumscribed ovoid orbital mass occupying...
Book Chapter
Series: Monographs in Clinical Cytology
Volume: 21
Published: 19 October 2011
10.1159/000331039
EISBN: 978-3-8055-9871-2
... is the mainstay of morphological diagnosis for orbital tumors in Stockholm, rarely being replaced as the primary procedure by open biopsy. Below there are comments on some of the specifics of FNA performed in more frequent tumors such as those of the lacrimal gland, lymphocytic tumors and tumors metastatic...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
EISBN: 978-3-8055-9419-6
...References References 1. Knop E, Knop N: A functional unit for ocular surface immune defense formed by the lacrimal gland, conjunctiva and lacrimal drainage system. Adv Exp Med Biol 2002;506:835-844 2. Knop E, Knop N: New techniques in lacrimal gland research: the magic juice and how...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 92
Published: 24 January 2007
10.1159/000099252
EISBN: 978-3-318-01404-4
... Abstract The ocular surface, in a strict sense, consists of the cornea and its major support tissue,the conjunctiva. In a wider anatomical, embryological, and also functional sense, theocular mucosal adnexa (i.e. the lacrimal gland and the lacrimal drainage system) alsobelong to the ocular...