... Abstract Many factors influence patients' perspectives on actinic keratosis (AK). The wish to keep a sense of control prompts many to seek information, which they then interpret according to their personal perspective. Speculations regarding the risk of getting skin cancer and emotional...

... Abstract Nonsurgical procedures are the first-line treatment for actinic keratosis (AK). The choice of therapy is based on AK features and patient characteristics. Numerous randomized clinical trials and open-label studies have provided robust data on the efficacy and tolerability...

... of suitable treatment for actinic keratosis (AK) depends on numerous factors, including the number and location of the lesions that have to be treated [ 6 , 7 . ]For the treatment of single lesions, treatment options like curettage or cryotherapy might be favourable. In contrast, PDT may be the first choice...

...: clinical research and future challenges. Cancer 1997;79:2282-2308. 3. Ko DY, Kim KH, Song KH: Comparative study of photodynamic therapy with topical methyl aminolevulinate versus 5-aminolevulinic acid for facial actinic keratosis with long-term follow-up. Ann Dermatol 2014;26:321-331. 4. Soret JL...

... Abstract This manuscript focuses on the use of mice to study the genetics and biology of cutaneous squamous cell carcinoma (SCC). Mice develop actinic keratosis-like lesions and SCC resembling those seen in humans. As an animal model, the mouse provides great experimental flexibility and has...

... of the epidermis; this variant is named bowenoid keratosis . If suprabasal clefts are present, AKs are named acantholytic . In pigmented AK , there is excess melanin deposition in both keratinocytes and melanocytes, and melanophages are present in the dermis. Melan-A is not a helpful marker for distinguishing...

... are easier to organise, require less-sophisticated technology and are more widely accessible and convenient for both patients and doctors. No study to date has focused solely on teledermatology for actinic keratosis, but such lesions are typically found during teledermatology examinations for other main...

... lesions, such as actinic keratosis [<citeref rid="ref6">6</citeref>]. Murine studies have shown that nicotinamide is also able to protect against photocarcinogenesis [<citeref rid="ref4">4</citeref>,<citeref rid="ref5">5</citeref>]. Preliminary human studies suggest...

... Abstract In the realm of keratinocyte skin cancer, specific dermoscopic patterns that are associated with different stages of progression have been identified, which allows for an improved clinical diagnosis and differentiation actinic keratosis, intraepidermal carcinoma (also commonly named...

... Yttrium Aluminium Garnet (Erbium YAG; 2,940 nm) laser systems, are used. In this chapter, the applicability and efficacy of various laser systems in the treatment of AK are discussed. Basic Aspects of Laser Treatments for Actinic Keratosis Laser systems emit coherent light of one wavelength...

... Abstract Ultraviolet (UV) radiation is likely to drive the initiation and progression of skin cancer from actinic keratosis to squamous cell carcinoma. Signs of photodamage occur at multiple steps. UV radiation damages many cellular constituents, including lipids, proteins and DNA, all of which...

... wound healing, the development of psoriasis-like lesions, structural and functional defects of hair follicles and tumourigenesis. Actinic keratosis, which is also known as solar keratosis, develops in sun-exposed areas of the skin. These are often called ‘premalignant lesions' and are said to represent...

... Abstract Squamous skin cancer, which is commonly called squamous cell carcinoma (SCC), represents an immunological puzzle. The major skin cancers (SCC, basal cell carcinoma, Merkel cell carcinoma, and melanoma) and actinic keratosis (AK), as a potential precursor lesion of SCC, are common...

... Abstract The incidence of non-melanoma skin cancer (NMSC), including actinic keratosis (AK), squamous cell carcinoma (SCC), Bowen's Disease (BD) and basal cell carcinoma (BCC), is increasing. UVA and UVB radiation lead to genetic alterations in keratinocytes, which eventually result in skin...

... Abstract Actinic keratosis is a common result of severe sun damage and is usually present on sun-exposed skin. Reflectance confocal microscopy is a non-invasive clinical imaging modality that results in quasi-histological, en face skin images. In this chapter, we review the available literature...

... Abstract Clinical assessment of actinic keratosis is known to be a variable process; however, there are currently no non-invasive alternatives for objectively assessing the condition besides excision and histopathology. While a number of technologies for examining potential actinic keratoses...

...References References 1. 1 Green A, Battistutta D: Incidence and determinants of skin cancer in a high risk Australian population. Int J Cancer 1990;15:356-361. 2. 2 Flohil SC, van der Leest RJ, Dowlatshahi EA, et al: Prevalence of actinic keratosis and its risk factors in the general...

...References References 1. 1 Memon AA, Tomenson JA, Bothwell J, et al: Prevalence of solar damage and actinic keratosis in a Merseyside population. Br J Dermatol 2000;142:1154-1159. 2. 2 Rosen T: Reexamination of field-directed therapy for actinic keratosis. Cutis 2012;90:163-165. 3...

...References References 1. 1 Yantsos VA, Conrad N, Zabawski E, et al: Incipient intraepidermal cutaneous squamous cell carcinoma: a proposal for reclassifying and grading solar (actinic) keratoses. Semin Cutan Med Surg 1999;18:3-14. 2. 2 Ackerman AB, Mones JM: Solar (actinic) keratosis...