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Book Chapter
Series: Contributions to Nephrology
Volume: 174
Published: 15 September 2011
10.1159/000329396
EISBN: 978-3-8055-9811-8
... Abstract Acute kidney injury (AKI) has been shown to be associated with progression to chronic kidney disease (CKD). Multiple studies have shown that subsets of AKI survivors are at high risk for progression to advanced stage CKD and death. Risk factors associated with AKI survivors progressing...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517694
EISBN: 978-3-318-06937-2
... Abstract Clinical Background: Automobile accidents constitute one of the main causes of morbidity and mortality worldwide. Kidney injury related to automobile accidents occurs through several mechanisms. Among the mechanisms are direct traumatic injury, rhabdomyolysis, acute renal failure...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445462
EISBN: 978-3-318-05884-0
... Abstract Approximately 70% of community-acquired cases of acute kidney injury are attributed to pre-renal causes. In most of these cases, the underlying kidney function may be normal, but decreased renal perfusion associated with low intravascular volume or decreased arterial pressure can...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445466
EISBN: 978-3-318-05884-0
... Abstract Acute tubular necrosis (ATN) is the most common type of acute kidney injury (AKI) related to parenchymal damage (90% of cases). It may be due to a direct kidney injury, such as sepsis, drugs, toxins, contrast media, hemoglobinuria and myoglobinuria, or it may be the consequence...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445467
EISBN: 978-3-318-05884-0
... Abstract Acute cortical necrosis and hemolytic uremic syndrome (HUS) are 2 clinical scenarios of parenchymal acute kidney injury (AKI) related to renal microvascular injury. Acute cortical necrosis is a rare condition related to an ischemic necrosis of renal cortex. Necrotic lesions can be due...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445468
EISBN: 978-3-318-05884-0
... Abstract The incidence of acute kidney injury related to urinary tract obstruction is low (1-10%). It occurs in bilateral renal or lower urinary tract obstruction or in ureter obstruction in patients with a single functioning kidney or with pre-existing chronic kidney disease. The etiology...
Book Chapter
Series: Contributions to Nephrology
Volume: 187
Published: 12 February 2016
10.1159/000442365
EISBN: 978-3-318-05826-0
... Abstract Recent controlled trials, epidemiological analyses and basic research studies offer a comprehensive view of the short and long-term clinical repercussion of de novo acute kidney injury or AKI. While most post-AKI patients recover their baseline renal function, a significant number...
Book Chapter
Series: Contributions to Nephrology
Volume: 182
Published: 14 May 2013
10.1159/000349963
EISBN: 978-3-318-02407-4
... Abstract Acute kidney injury (AKI) commonly occurs in hospitalized patients and is independently and strongly associates with morbidity and mortality. The clinical benefits of a timely and definitive diagnosis of AKI have not been fully realized due to limitations imposed by the use of serum...
Book Chapter
Series: Contributions to Nephrology
Volume: 174
Published: 15 September 2011
10.1159/000329238
EISBN: 978-3-8055-9811-8
... Abstract Acute kidney injury (AKI), acute lung injury (ALI) and sepsis are all commonly encountered in critically ill patients. Although considered as separate conditions, largely for therapeutic purposes, a common inflammatory response is often implicated in their pathophysiologies...
Book Chapter
Series: Contributions to Nephrology
Volume: 165
Published: 04 May 2010
10.1159/000313740
EISBN: 978-3-8055-9473-8
... Abstract Septic acute kidney injury (AKI) is the most common form of AKI seen in critically ill patients in developed countries. Its pathogenesis has been traditionally attributed to ischemia secondary to decreased cardiac output and hypotension, which trigger sustained renal vasoconstriction...
Book Chapter
Series: Contributions to Nephrology
Volume: 156
Published: 10 May 2007
10.1159/000102124
EISBN: 978-3-318-01456-3
... Abstract Fortunately with improvements in initial medical resuscitation, such as the avoidanceof nephrotoxins, the incidence of acute kidney injury requiring renal support in patients withacute traumatic brain injury remains low. However the incidence of cerebral hemorrhage inpatients...
Book Chapter
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517701
EISBN: 978-3-318-06937-2
... Abstract Clinical Background: Clinical infections and its most severe forms sepsis and septic shock are commonly associated with changes in kidney function. This acute kidney injury (AKI) is associated with increased risk of morbidity and mortality in hospitalized patients. Epidemiology...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517699
EISBN: 978-3-318-06937-2
... Abstract Clinical Background: Nephrotoxic acute kidney injury or toxin-related acute kidney injury (ToxAKI) is a relevant and relatively common category of kidney damage. Exogenous toxins and venomous animals with epidemiologic variations across the world are some nephrotoxic agents...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517697
EISBN: 978-3-318-06937-2
... Abstract Obstetric-related acute kidney injury (obstetric AKI) is an important and complex public health problem; its early recognition and proper treatment are key in preventing maternal and fetal adverse outcomes. While the incidence of obstetric AKI has drastically declined in some...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517725
EISBN: 978-3-318-06937-2
... Abstract Snakebite-related acute kidney injury (AKI) is mainly caused by bites from the Viperidae family which are common snakes worldwide. It is a frequent and potentially fatal clinical complication. Coagulation abnormalities are usually present and are most likely to contribute to AKI...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 7
Published: 09 September 2019
10.1159/000500379
EISBN: 978-3-318-06540-4
... Abstract Acute kidney injury (AKI) is a prominent feature of leptospirosis, characterized by tubulo-interstitial nephritis and tubular dysfunction. Nonoliguric hypokalemic form of AKI is a hallmark of leptospiral nephropathy. Arrhythmias are the most important cardiac manifestations...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 7
Published: 09 September 2019
10.1159/000500382
EISBN: 978-3-318-06540-4
... Abstract Pathogenic species of Leptospira cause leptospirosis, a global zoonotic disease. The kidney is the main target of Leptospira during both acute and chronic infections, as the conditions in the renal tubules favor Leptospira survival. Acute kidney injury with characteristic...
Book Chapter
Series: Contributions to Nephrology
Volume: 193
Published: 08 February 2018
10.1159/000484956
EISBN: 978-3-318-06311-0
... Abstract Background: The acute reduction of kidney function in critically and noncritically ill patients (regardless of their age) is one of the deadliest clinical conditions ever reported in modern medicine. Acute kidney injury (AKI) symptoms are sneaky and potentially difficult...