... with time. In an RCT, HA330 was applied to 44 septic patients as a stand-alone approach. HP was performed during 2 h, once a day, for 3 consecutive days, with a blood flow rate between 100 and 200 mL/min [ 14 ]. HP with HA330 induced a decrease in IL-6 and IL-8 blood levels. In addition, an improvement...

..., prostaglandins, leukotrienes, vasopressors, platelet activation products, and complement induces vascular damage and vessel thrombosis. Then, tumor necrosis factor alpha (TNF-α) induces cell apoptosis, and, finally, sequestered leukocytes in the burn tissues release proinflammatory mediators, thus fueling...

...: the use of systematic ultrasound guidance for the insertion of dialysis catheters and the use of RCA instead of systemic heparin anticoagulation. Hypothermia induced by CRRT and complications associated with prolonged bed rest are also better controlled today. Finally, the removal of undesired substances...

... Abstract Cancer therapy-induced bone loss (CTIBL), occurring especially in hormone-treated breast and prostate cancer patients, is a noteworthy long-term consequence of cancer treatments. Because of its negative impact on the quality life of cancer survivors, it deserves much attention. We here...

..., and pregnancy-induced complications such as gestational diabetes mellitus. In this paragraph, the authors reviewed the literature concerning the application of metabolomics in the investigation of gestational diabetes, summarized the most relevant findings, and hypothesized possible future utilizations...

... were found [ 9 , 10 ]. Finally, it was demonstrated that bifidobacteria in infants suffering from atopic dermatitis induces a higher secretion of proinflammatory cytokines, while those of healthy infants induce a higher secretion of anti-inflammatory cytokines [ 11 ]. Starting from these data...

... Abstract Laser-induced interstitial thermotherapy (LITT) is a modern minimally invasive treatment modality applied for management of a variety of diseases. Recent developments of techniques for precise targeting of the lesion, accurate delivery of the prescribed therapeutically effective...

... in patients exposed to glucocorticoid excess, although some peculiarities of this treatment should be taken into account to avoid under-treatment of hypovitaminosis D in the specific clinical context of glucocorticoid-induced osteoporosis. This chapter deals with pathophysiological, clinical, and therapeutic...

... Abstract Drug-induced sleep endoscopy was introduced in 1991 and has recently evolved into a pivotal instrument for patients in whom obstructive sleep apnea surgery is considered. Here, we discuss the indications, contraindications, technique, anesthesia, scoring systems, validity, and insights...

... Abstract Drugs may cause itching as a concomitant symptom of drug-induced skin reactions or in the form of pruritus without skin lesions. Drug-induced itch is defined as generalized itching without skin lesions, caused by a drug. Itching associated with drug-induced cholestasis is among...

... Abstract Differentiated somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) via transduction of transcription factors or small molecule compounds. Similar to embryonic stem cells, iPSCs have the capacity to differentiate into any type of cell in the body. Because...