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immunoglobulin

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Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505335
EISBN: 978-3-318-06685-2
... Abstract Secretory immunoglobulin A (SIgA) is intimately involved in the transfer of maternal immunity to the newborn breastfed infant. Recent research demonstrates the significance of SIgA in the initial development of the newborn’s microbiota and in the establishment of a tolerogenic...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 100
Published: 27 May 2014
10.1159/000358621
EISBN: 978-3-318-02195-0
... Abstract Immunoglobulin E (IgE) was discovered in 1967. Today, more than 40 years after the discovery, the normal beneficial function in the body of this enigmatic immunoglobulin still remains unclear. However, ever since the discovery new knowledge about allergic diseases and allergens, new...
Book Chapter
Series: Contributions to Nephrology
Volume: 169
Published: 14 January 2011
10.1159/000314778
EISBN: 978-3-8055-9538-4
... Abstract Light, light and heavy, and heavy chain deposition diseases (LCDD, LHCDD and HCDD, respectively) belong to a family of diseases featuring deposition in the kidney of a monoclonal immunoglobulin (Ig) or its isolated subunits, which also includes light chain amyloidosis, non-amyloid...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 93
Published: 20 March 2007
10.1159/000100858
EISBN: 978-3-318-01451-8
... is synthesized in low concentrations by the human liver, and is increased inbiological fluids of patients with viral hepatitis. This protein binds with high affinity to thevariable domain of the heavy chains of all human immunoglobulins. Thus, it is an endogenousimmunoglobulin superantigen because it binds...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 93
Published: 20 March 2007
10.1159/000100861
EISBN: 978-3-318-01451-8
... hypermutation, class switching to immunoglobulin (Ig) E andthe production of allergen-specific IgE in mucosal B cells. IgE antibodies directed against thesuperantigens (‘superallergens’) themselves engender chronic inflammation and the persistentsensitization to conventional allergens of mast cells and antigen...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 65
Published: 22 January 2007
10.1159/000098678
EISBN: 978-3-318-01343-6
... patients. Different serum dilutions were testedfor neutralizing activity against constant MV concentration. Nearly complete viral neutralizationwas achieved with samples containing inactivated complement and in immunoglobulin-Gcontainingfractions, and activity in sera from patients with confirmed...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 153
Published: 03 November 2006
10.1159/000096768
EISBN: 978-3-318-01397-9
... Abstract Amyloidosis is a disease in which abnormal proteins form toxic intermediates and fibrillartissue-deposits that compromise key viscera and lead to early death. In order to treat amyloidosis,the type of abnormal protein must be identified. The most common type ismonoclonal immunoglobulin...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 88
Published: 11 August 2005
10.1159/000087829
EISBN: 978-3-318-01233-0
... Abstract Immunological disturbances play a role in the majority of patients with recurrentmiscarriage (RM) and therefore treatment with intravenous immunoglobulin (IvIg) has beentested in patients with RM in several trials. Seven placebo-controlled trials that wereextremely heterogeneous...
Book Chapter
Book Chapter
Book Chapter
Book Chapter
Published: 17 August 1995
10.1159/000424872
EISBN: 978-3-318-04777-6
... Abstract Immunoglobulin heavy chain (Gm) and light chain (Km) allotypes have been extensively studied as possible markers of susceptibility to a range of immune-related diseases including malignancies, infectious diseases and autoimmune disorders. This review is concentrated on susceptibility...
Book Chapter
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 59
Published: 23 August 1994
10.1159/000319254
EISBN: 978-3-318-01898-1
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 59
Published: 23 August 1994
10.1159/000423694
EISBN: 978-3-318-01898-1
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Book Chapter
Series: Current Studies in Hematology and Blood Transfusion
Volume: 57
Published: 19 September 1990
10.1159/000418553
EISBN: 978-3-318-03527-8
Book Chapter