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Book Chapter
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 167
Published: 02 June 2010
10.1159/000315917
EISBN: 978-3-8055-9485-1
... through ionic and hydrophobic interactions. Intravenous injection of PL-B has significant nephrotoxic and neurotoxic effects. However, covalently immobilized PL-B on the adsorbents of PMX do not leak out into the blood stream, thus allowing the clinical application without the known toxic effects of PL-B...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 88
Published: 11 August 2005
10.1159/000087819
EISBN: 978-3-318-01233-0
... Abstract Complement-dependent sperm-immobilizing antibodies (SI-Abs) have frequently beendetected in the sera of infertile women. Analyses using monoclonal antibodies as well aspatients’ antisperm antibodies have shown that the carbohydrate moieties of sperm and seminalplasma are major epitopes...
Book Chapter
Series: Contributions to Nephrology
Volume: 156
Published: 10 May 2007
10.1159/000102138
EISBN: 978-3-318-01456-3
... hemoperfusionwith polymyxin-B-immobilized fiber (PMX-F) is a promising treatment of gramnegativesepsis in critically ill patients. Because of the high affinity of polymyxin B forendotoxin, the rationale underlying extracorporeal therapy would be to remove circulating endotoxinby adsorption, thus preventing...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 167
Published: 02 June 2010
10.1159/000315920
EISBN: 978-3-8055-9485-1
... dysfunction [ 4 ]. Removal of circulating LPS by hemoperfusion through an immobilized polymyxin B (PMX-B) column has been shown to improve septic outcome and reduce the incidence of septic-induced ARF [ 5 - 7 ]; however, some physicians are hesitant to initiate the widespread application of this novel therapy...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
10.1159/000485725
EISBN: 978-3-318-06298-4
... by the polymyxin B-immobilized fiber column (PMX). PMX has been used for decades in Europe. Results of a North American randomized controlled trial (RCT) on PMX have recently been announced in a press release; results of large-scale observational studies and meta-analyses have also been reported in the last...
Book Chapter
Book Chapter
Book Chapter
Book Chapter
Series: Progress in Neurological Surgery
Volume: 34
Published: 28 May 2019
10.1159/000493046
EISBN: 978-3-318-06422-3
... of the intersection of the ionizing radiation beams that create the radiobiological effect. Non-invasive immobilization systems first proposed for linear accelerator or proton radiation technologies have now been developed for the Leksell Gamma Knife ICON radiosurgical system. The ICON technology adds a cone-beam...
Book Chapter
Series: Contributions to Nephrology
Volume: 200
Published: 07 August 2023
10.1159/000527708
EISBN: 978-3-318-07124-5
... with a technique to eliminate exposure. Polymyxin is bound and immobilized to fibers within a cartridge and administered as an extracorporeal therapy via veno-venous hemoperfusion. Clinical evidence of its use is plentiful yet inconsistent in studies based on an outcome for mortality at 28 days. Herein, we...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 75
Published: 15 August 2013
10.1159/000345818
EISBN: 978-3-318-02333-6
... response. Excessive anti-inflammatory measures may impair recovery. Many injuries result in limb immobilization. Immobilization results in muscle loss due to increased periods of negative muscle protein balance from decreased basal muscle protein synthesis and resistance to anabolic stimuli, including...
Book Chapter
Series: Contributions to Nephrology
Volume: 167
Published: 02 June 2010
EISBN: 978-3-8055-9485-1
...:108-114 5. Cruz DN, Bellomo R, Ronco C: Clinical effects of polymyxin B-immobilized fiber column in septic patients. Contrib Nephrol 2007;156:444-451 6. Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C: Effectiveness...
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
EISBN: 978-3-318-06298-4
...-controlled study of a polymyxin B-immobilized hemoperfusion cartridge in patients with severe sepsis secondary to intra-abdominal infection. Shock 2005;23:400-405. 9. Cruz DN, Antonelli M, Fumagalli R, Foltran F, Brienza N, Donati A, Malcangi V, Petrini F, Volta G, Bobbio Pallavicini FM, Rottoli F...
Book Chapter
Series: Contributions to Nephrology
Volume: 200
Published: 07 August 2023
EISBN: 978-3-318-07124-5
..., Fushimi K. Effectiveness of polymyxin B hemoperfusion for sepsis depends on the baseline SOFA score: a nationwide observational study. Ann Intensive Care. 2021 Dec;11(1):141. 26. Tanaka T, Tabata T, Fujino K, Tsujita Y, Eguchi Y. Impact of timing of polymyxin B-immobilized fiber column direct...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 32
Published: 03 July 2013
10.1159/000346424
EISBN: 978-3-318-02309-1
... damage to the motor neuron tract and partly from disuse muscle atrophy in paretic and nonparetic legs. Disuse muscle atrophy occurs even in healthy subjects as early as 4 days after bed rest immobilization and progresses further correlating with the duration of immobilization. Although detailed...
Book Chapter
Series: Contributions to Nephrology
Volume: 167
Published: 02 June 2010
EISBN: 978-3-8055-9485-1
...: endotoxin adsorption cartridge (Toraymyxin). Ther Apher Dial 2003;7:108-114 16. Aoki H, Kodama M, Tani T, Hanasawa K: Treatment of sepsis by extracorporeal elimination of endotoxin using polymyxin B-immobilized fiber. Am J Surg 1994;167:412-417 17. Cruz DN, Perazella MA, Bellomo R, et al...