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icodextrin

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Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
10.1159/000337790
EISBN: 978-3-318-02163-9
... Abstract Proper volume management continues to be a major challenge in patients requiring renal replacement therapy. In patients performing peritoneal dialysis the introduction of icodextrin represented a major advance in this effort. Recent studies have demonstrated a potential role...
Book Chapter
Series: Contributions to Nephrology
Volume: 150
Published: 12 May 2006
10.1159/000093508
EISBN: 978-3-318-01347-4
... Abstract Icodextrin is the only large molecular weight osmotic agent available in peritoneal dialysissolutions. Icodextrin (compared to glucose) has a prolonged positive ultrafiltrationbecause of the slow absortion of icodextrin due to its large molecular weight. As icodextrininduces...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
EISBN: 978-3-318-02163-9
... peritoneal dialysis patient populations. JASN 2006;17:271-278 4. Lin A, Qian J, Li X, Yu X, Liu W, Sun Y, Chen N, Mei C: Randomized controlled trial of icodextrin versus glucose containing peritoneal dialysis fluid. CJASN 2009;4:1799-1804 5. Jenkins S, Wilkie M: An exploratory study of a novel...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
10.1159/000337792
EISBN: 978-3-318-02163-9
... conventional PD fluids induce severe morphological and functional alterations of the peritoneal membrane within a few years, reduction of glucose degradation product content by multichamber systems, replacement of glucose by icodextrin and amino acids, and of lactate by bicarbonate at a neutral...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
EISBN: 978-3-318-02163-9
... hemodynamics as compared with icodextrin. Nephrol Dial Transplant 2005;20:1848-1853 6. Mistry CD, Gokal R, Peers E: A randomized multicenter clinical trial comparing isosmolar icodextrin with hyperosmolar glucose solutions in CAPD. MIDAS study group. Multicenter investigation of icodextrin in ambulatory...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
10.1159/000337784
EISBN: 978-3-318-02163-9
... of them is without side effects: glucose is relatively safe and brings additional energy but induces anorexia and lipid abnormalities, amino acids compensate dialysate losses but may increase uremia and acidosis, icodextrin helps control hyperhydration and chronic heart failure and minimizes glucose side...
Book Chapter
Series: Contributions to Nephrology
Volume: 185
Published: 26 May 2015
10.1159/000380975
EISBN: 978-3-318-05465-1
...% of PD patients were using the poly-glucose dialysis solution icodextrin (Extraneal). Around 40% of PD patients were using icodextrin, a much higher percentage than in other countries. What is the likelihood that the number of PD patients in Japan will gradually decrease (or increase) in the future...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
10.1159/000337809
EISBN: 978-3-318-02163-9
... to obtain a sufficient ultrafiltration volume to maintain a euvolemic state without using large amount of hypertonic glucose solution can cause peritoneal dialysis failure. New approaches in the use of icodextrin to increase ultrafiltration and sodium removal are under investigation. A novel modality...
Book Chapter
Series: Contributions to Nephrology
Volume: 150
Published: 12 May 2006
10.1159/000093502
EISBN: 978-3-318-01347-4
... a day, during 30 consecutive days withHank’s balanced salt solution. Groups 4 and 5 - same experimental protocol, but injecting4.25% glucose single bag or 7.5% Icodextrin PDF. Imprints and/or biopsies were taken aftera recovery period of 15 days, counted from the last IP injection. Results: Density...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
EISBN: 978-3-318-02163-9
... in peritoneal dialysis fluids. Perit Dial Int 2006;26:490-497 11. De Boer AW, Schröder CH, Van Vliet R: , et al Clinical experience with icodextrin in children: ultrafiltration profiles and metabolism. Pediatr Nephrol 2000;15:21-24 12. van Hoeck KJ, Rusthoven E, Vermeylen L: , et al Nutritional effects...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
EISBN: 978-3-318-02163-9
...-127 11. Van Biesen W, Verbeke F, Vanholder R: Cardiovascular disease in haemo-dialysis and peritoneal dialysis: arguments pro peritoneal dialysis. Nephrol Dial Transplant 2007;22:53-58 12. Qi H, Xu C, Yan H, Ma J: Comparison of icodextrin and glucose solutions for long dwell exchange...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
10.1159/000337890
EISBN: 978-3-318-02163-9
... in achieving dietary compliance with salt and fluid restriction, improving fluid status and minimizing the use of hypertonic glucose solution [ 23 ]. A recently published randomized control trial compared the effects of Icodextrin (ICO) and glucose-based solutions (GLU) in 41 Japanese patients with ESRD...
Book Chapter
Series: Contributions to Nephrology
Volume: 198
Published: 07 May 2019
10.1159/000496523
EISBN: 978-3-318-06424-7
... comprises systematic reviews and recommendations on clinical questions (CQs) according to the GRADE system. Six CQs are included in Part 2: CQ1. Are renin-angiotensin inhibitors useful in the management of PD? CQ2. Is combination of icodextrin solution with glucose-based solution useful...
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
10.1159/000485715
EISBN: 978-3-318-06298-4
... like icodextrin to optimize volume control are important. PD patients whose BP is consistently >140/90 mm Hg should be treated to maintain SBP at <140 mm Hg and DBP at <90 mm Hg. There are no randomized studies examining different BP targets in relation to clinical outcomes in PD patients...
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
10.1159/000485689
EISBN: 978-3-318-06298-4
... peritonitis as a factor for the development of EPS associated with icodextrin, which is widely used in Japan [ 24 ], and another report on the possibility that the acidity of PD solution (pH: 5.0) can damage peritoneal cells [ 25 ]. The pathogenesis of these complexes is still unclear in many aspects...
Book Chapter
Series: Contributions to Nephrology
Volume: 198
Published: 07 May 2019
EISBN: 978-3-318-06424-7
... disease in the era of icodextrin treatment. Eur J Intern Med 2018; 50: 69–74. 11. Wang IK, Li YF, Chen JH, Liang CC, Liu YL, Lin HH, Chang CT, Tsai WC, Yen TH, Huang CC: Icodextrin decreases technique failure and improves patient survival in peritoneal dialysis patients. Nephrology (Carlton) 2015; 20...
Book Chapter
Series: Contributions to Nephrology
Volume: 178
Published: 30 May 2012
10.1159/000337850
EISBN: 978-3-318-02163-9
... on the extracellular/intracellular water distribution. This is an instrument that can be longitudinally used to improve the accuracy of clinical judgment concerning volume status. Incremental PD with use of icodextrine besides the promising role of low sodium solutions and bimodal solutions are therapy issues that can...
Book Chapter
Series: Contributions to Nephrology
Volume: 185
Published: 26 May 2015
EISBN: 978-3-318-05465-1
..., Yamabe K, Kawaguchi Y: Successful use of Icodextrin in patients on CAPD. Adv Perit Dial 2005;21:168-174. 8. Babazono T, Nakamoto H, Kasai K, Kuriyama S, Sugimoto T, Nakayama M, Hamada C, Furuya R, Hasegawa H, Kasahara M, Moriishi M, Tomo T, Miyazaki M, Sato M, Yorioka N, Kawaguchi Y, for the Japanese...
Book Chapter
...Literatur Literatur 1. Davies SJ, Woodrow G, Donovan K, Plum J, Williams P, Johansson AC, et al: Icodextrin improves the fluid status of peritoneal dialysis patients: results of a double-blind randomized controlled trial. J Am Soc Nephrol 2003;14:2338-2344. 2. Del Peso G, Jimenez...