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hypoparathyroid

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Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491043
EISBN: 978-3-318-06409-4
... Abstract The term hypoparathyroidism encompasses a huge group of disorders all characterized by an abnormal mineral homeostasis determined by inadequate secretion of parathyroid hormone. Postsurgical hypoparathyroidism is a complication of neck surgery (thyroidectomy, parathyroidectomy, lymph...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491042
EISBN: 978-3-318-06409-4
... glands primarily in response to a decline in serum calcium levels. The causes of hypocalcemia can be broadly classified as inadequate PTH or vitamin D production, PTH resistance, or miscellaneous causes. The term “hypoparathyroidism” refers to a metabolic disorder in which hypocalcemia...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491044
EISBN: 978-3-318-06409-4
... Abstract Parathyroid hormone (PTH) is one of the major hormones that regulates serum calcium. Hypoparathyroidism occurs when PTH secretion is insufficient. The main symptoms of hypoparathyroidism are the result of low blood calcium levels, hypocalcemia, which interferes with normal muscle...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491046
EISBN: 978-3-318-06409-4
... Abstract The treatment of hypoparathyroidism depends on the severity of hypocalcemia, how rapidly the hypocalcemia developed, and the symptomatology. Chronic hypoparathyroidism is usually treated with oral supplementations, including calcium, calcitriol, or other active vitamin D analogs...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
10.1159/000486075
EISBN: 978-3-318-06339-4
... Abstract Hypoparathyroidism is a rare endocrine disorder characterized by hypocalcemia due to absent or insufficient levels of circulating parathyroid hormone (PTH). By far, the most common cause of the disease is iatrogenic, after anterior neck surgery, followed in incidence by autoimmune...
Book Chapter
Series: Progress in Surgery
Volume: 18
Published: 07 May 1986
10.1159/000412370
EISBN: 978-3-318-04148-4
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491047
EISBN: 978-3-318-06409-4
... Abstract Several studies have investigated replacement therapy with recombinant human parathyroid hormone [rhPTH(1-84)] for patients affected by chronic hypoparathyroidism who are not adequately controlled with standard treatment. In 2015, the Food and Drug Administration (FDA) in the USA...
Book Chapter
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
EISBN: 978-3-318-06409-4
...References References 1. Bilezikian JP, Khan A, Potts JT Jr, Brandi ML, Clarke BL, Shoback D, Jüppner H, D'Amour P, Fox J, Rejnmark L, Mosekilde L, Rubin MR, Dempster D, Gafni R, Collins MT, Sliney J, Sanders J: Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
EISBN: 978-3-318-06409-4
...References References 1. Brandi ML, Bilezikian JP, Shoback D, Bouillon R, Clarke BL, Thakker RV, Khan AA, Potts JT Jr: Management of hypoparathyroidism: summary statement and guidelines. J Clin Endocrinol Metab 2016;101:2273-2283. 2. Bilezikian JP, Khan A, Potts JT Jr, Brandi ML, Clarke...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
EISBN: 978-3-318-06339-4
...References References 1. Shoback DM, Bilezikian JP, Costa AG, Dempster D, Dralle H, Khan AA, Peacock M, Raffaelli M, Silva BC, Thakker RV, Vokes T, Bouillon R: Presentation of hypoparathyroidism: etiologies and clinical features. J Clin Endocrinol Metab 2016;101:2300-2312. 2. Al-Azem H...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
EISBN: 978-3-318-06409-4
...References References 1. Shoback D: Clinical practice. Hypoparathyroidism. N Engl J Med 2008;359:391-403. 2. Brandi ML, Bilezikian JP, Shoback D, Bouillon R, Clarke BL, Thakker RV, Khan AA, Potts JT Jr: Management of hypoparathyroidism: summary statement and guidelines. J Clin Endocrinol...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
EISBN: 978-3-318-06409-4
...References References 1. Brandi ML, Bilezikian JP, Shoback D, Bouillon R, Clarke BL, Thakker RV, Khan AA, Potts JT Jr: Management of hypoparathyroidism: summary statement and guidelines. J Clin Endocrinol Metab 2016;101:2273-2283. 2. Bollerslev J, Rejnmark L, Marcocci C, Shoback DM...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
EISBN: 978-3-318-06409-4
..., Khan AA, Potts JT Jr, Brandi ML, Clarke BL, Shoback D, Jüppner H, D'Amour P, Fox J, Rejnmark L, Moseklide L, Rubin MR, Dempster D, Gafni R, Collins MT, Sliney J, Sanders J: Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges...
Book Chapter
Series: Endocrine Development
Volume: 28
Published: 11 June 2015
EISBN: 978-3-318-05467-5
...References References 1. Fonseca OA, Calverley JR: Neurological manifestations of hypoparathyroidism. Arch Intern Med 1967;120:202-206. 2. Schaaf M, Payne CA: Effect of diphenylhydantoin and phenobarbital on overt and latent tetany. N Engl J Med 1966;274:1228-1233. 3. Shaw NJ...
Book Chapter
Series: Endocrine Development
Volume: 28
Published: 11 June 2015
10.1159/000380997
EISBN: 978-3-318-05467-5
... laboratories as a marker of bone turnover. This factor is often elevated when hypocalcaemia is secondary to a disorder of vitamin D and is often within the normal range when hypocalcaemia is secondary to hypoparathyroidism. Plasma creatinine is an essential measure to exclude the possibility of renal failure...
Book
Book Cover Image
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/isbn.978-3-318-06409-4
EISBN: 978-3-318-06409-4
Book Chapter
Book Chapter
Series: Endocrine Development
Volume: 16
Published: 17 June 2009
10.1159/000223697
EISBN: 978-3-8055-9162-1
... which alter the balance between bone accretion and reabsorption mainly by temporarily reducing the activity of osteoclasts. Vitamin D and its metabolites are used for the treatment of various forms of rickets and vitamin D deficiency and the active metabolites are also employed when hypoparathyroidism...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 49
Published: 26 April 2018
10.1159/000486003
EISBN: 978-3-318-06335-6
... cortex cells, where it may play a role in controlling body energy, blood pressure, and metabolism. Cardiometabolic features have been investigated in the wide spectrum of clinical parathyroid disorders, from hyperparathyroidism to pseudohypoparathyroidism and hypoparathyroidism. Indeed, in parathyroid...