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hormone

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Book Chapter
Series: Frontiers of Hormone Research
Volume: 48
Published: 09 March 2017
10.1159/000452913
EISBN: 978-3-318-06014-0
... Abstract Most scientific reports debate the thymotropic and immuno-stimulating properties of the somatotrope growth hormone-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor (IGF)-1 axis, but there is still some disagreement about the physiological role of this axis...
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Series: Frontiers of Hormone Research
Volume: 54
Published: 17 December 2021
10.1159/000515111
EISBN: 978-3-318-06791-0
... Abstract Growth hormone deficiency (GHD) is common in childhood cancer survivors (CCS). Major risk factors for GHD include radiation therapy, both cranial and total body irradiation, and tumor location. Some newer anti-cancer therapies may impact growth and the GH-IGF-1 axis as well. While...
Book Chapter
Series: Endocrine Development
Volume: 11
Published: 20 November 2007
10.1159/000111053
EISBN: 978-3-8055-8348-0
... Abstract The central feature of growth hormone (GH) insensitivity is deficiency of insulin-likegrowth factor-1 (IGF-1) in association with elevated GH secretion. This condition is alsoknown as primary IGF deficiency. There are currently four known genetic causes of GHinsensitivity/primary IGF...
Book Chapter
Series: Endocrine Development
Volume: 11
Published: 20 November 2007
10.1159/000111055
EISBN: 978-3-8055-8348-0
... Abstract Many variables influence the outcome of growth hormone (GH) therapy (GH dose andduration, height - SDS at treatment start or at puberty onset, bone age, mid parental height,growth velocity, age, etc.). Nevertheless, all these factors only partially explain...
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Series: Frontiers of Hormone Research
Volume: 35
Published: 21 June 2006
10.1159/000094310
EISBN: 978-3-318-01379-5
... Abstract During the last century, the questions posed by scientists and clinicians on pituitaryfunction have led to new concepts about the mechanisms of hormone action and cell differentiation.In particular, the advent of molecular genetics and the cloning of pituitary hormonecoding genes...
Book Chapter
Series: Endocrine Development
Volume: 9
Published: 10 May 2005
10.1159/000085759
EISBN: 978-3-318-01215-6
... Abstract Decisions on growth hormone (GH) dosing in paediatric practice have depended onbody weight or surface area calculations. Although this policy was used initially in the treatmentof adult patients, it has become apparent both in clinical studies and longitudinal observationthat...
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