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Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519388
EISBN: 978-3-318-07015-6
... Abstract The benefits of breastfeeding, such as reduced risk of gastrointestinal and respiratory tract infections, depend largely on the presence of bioactive compounds in breast milk, including human milk oligosaccharides (HMOs). The presence of HMOs represents one of the largest differences...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519390
EISBN: 978-3-318-07015-6
... determinants, and were associated with short- and long-term outcome. In another study, the effects of caesarean birth on infant gut microbiota could be alleviated by human milk oligosaccharides (HMOs) in mothers’ milk. In addition, 58 infants fed with a formula enriched with 2 HMOs had microbiota closer...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490306
EISBN: 978-3-318-06341-7
... Abstract Human milk oligosaccharides (HMOs) are the third most abundant component of human milk. So far, more than 150 different and structurally distinct HMOs have been identified. HMO composition varies substantially between women, but remains fairly constant over the course of lactation...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490292
EISBN: 978-3-318-06341-7
... Abstract Human milk oligosaccharides (HMOs) are elongations of the milk sugar lactose by galactose, N-acetylglucosamine, fucose; and sialic acid. The HMO composition of breast milk is strongly influenced by polymorphisms of the maternal fucosyltransferases, FUT2 and FUT3, and by the stage...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 97
Published: 12 May 2023
10.1159/000528992
EISBN: 978-3-318-07170-2
... Abstract Human milk contains all nutritive and bioactive compounds to give infants the best possible start in life. Human milk bioactives cover a broad range of components, including immune cells, antimicrobial proteins, microbes, and human milk oligosaccharides (HMOs). Over the last decade...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519396
EISBN: 978-3-318-07015-6
... is the most important factor shaping the gut microbiome, in particular receipt of human milk. Human milk contains viable bacteria and numerous components that modulate the bacterial community, including human milk oligosaccharides (HMOs) which promote the growth of Bifidobacterium species. Notably...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
10.1159/000455398
EISBN: 978-3-318-06031-7
... Abstract It is a great success that biotechnological means are available today to produce amounts of single human milk oligosaccharides (HMOs) in a purity which allows performing metabolic and functional studies even in humans. As recent data indicate that there is a link between the Lewis...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
10.1159/000518201
EISBN: 978-3-318-06296-0
... Human milk oligosaccharides Secretors Nonsecretors Synbiotics Infant health Key Messages Human milk oligosaccharides (HMOs) are a group of more than 150 different unconjugated carbohydrates (glycans), and their composition varies greatly between women and is dynamic over...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505339
EISBN: 978-3-318-06685-2
... Abstract Oligosaccharides are a group of complex glycans that are present in the milk of most mammals. However, human milk is unique as the concentrations of human milk oligosaccharides (HMOs) are much higher than those of other mammals, and their structural composition is more complex...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519405
EISBN: 978-3-318-07015-6
... in particular. At the same time, challenges create opportunities for potential interventions to help shape healthy microbial communities. Interventions include the use of human milk, the use of specific human milk bioactives like human milk oligosaccharides (HMOs), as well as the use of probiotics...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505551
EISBN: 978-3-318-06685-2
..., and this session intended to highlight recent research on some of the soluble components in human milk and the mechanisms behind their protective actions. Lars Bode started this session by presenting the biosynthesis and structure of human milk oligosaccharides (HMOs), and how they can vary among women...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505338
EISBN: 978-3-318-06685-2
... norovirus strains. In our current work, we tried to decipher the HBGA specificity of the most prevalent and clinically relevant norovirus GII.4 subfamily (Sydney 2012, JX459908) and its preferences for human milk oligosaccharides (HMOs) as potential anti-infectives. The structural evidence provided can...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519416
EISBN: 978-3-318-07015-6
... in preterm and low birth weight infants, including human milk oligosaccharides (HMOs) and their potential impact on the health of neonates. Speakers discussed the best-in-class nutritional strategies to optimize feeding, nutrition, and growth in preterm infants during their intensive care period...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
10.1159/000455400
EISBN: 978-3-318-06031-7
...-neotetraose and 2-fucosyllactose with safety assessment in European Union and United States. Introduction Human milk oligosaccharides (HMOs) are a group of sugars which are structurally diverse unconjugated glycans. They are found in human milk with a composition unique to each lactating mother [ 1...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519403
EISBN: 978-3-318-07015-6
... milk oligosaccharides (HMOs), growth, body composition, and long-term metabolic and cognitive outcomes. To bring us together requires a huge amount of effort and resource, and there are few forums to do this. The NNI workshop facilitated interactions between scientists, translation workers...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 96
Published: 30 June 2022
10.1159/000519401
EISBN: 978-3-318-07015-6
... that it brings into human milk [ 4 ]. Broad categories of bioactive components in breastmilk include immunological and growth factors. Immunological factors include immune cells such as T cells and lymphocytes, cytokines, secretory immunoglobulin A (sIgA), and human milk oligosaccharides (HMOs) [ 1 ]. Growth...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 98
Published: 21 March 2024
10.1159/000534995
EISBN: 978-3-318-07263-1
... nutrition, particularly through breastfeeding support, emerges as a paramount strategy for infant care. In cases where formula feeding is necessary, the utilization of low protein formulas and supplementation with human milk oligosaccharides (HMOs) have demonstrated favorable outcomes. Furthermore, adopting...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505425
EISBN: 978-3-318-06685-2
... oligosaccharides (HMO) with respect to disease expression in the neonate after exposure to allergens and infectious agents. She discussed in some detail the enzyme fucosyltransferase (FUT) and its genotypes FUT2 and FUT3. These enzymes are expressed on blood groups ABH and Lewis, intestinal mucosa, and other human...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490484
EISBN: 978-3-318-06341-7
... explained how human milk oligosaccharides (HMOs) are synthesized in the mammary gland and how polymorphism in genes involved as well as stage of lactation can affect their composition in breast milk. Several observational and basic research studies strongly suggest that HMOs influence early-life microbiota...
Book
Book Cover Image
Published: 03 December 1999
10.1159/isbn.978-3-318-00498-4
EISBN: 978-3-318-00498-4