... attracts macrophages to the tumor [ 6 ]. The genetic change can be detected by cytogenetics, FISH, PCR, and consequently NGS (next-generation sequencing), on fresh and fixated material. Differential Diagnosis • Deep benign fibrous histiocytoma • Reactive synovial hyperplasia • Giant cell...

...References References 1. Walaas L, Angervall L, Hagmar B, Save-Soderbergh J: A correlative cytologic and histologic study of malignant fibrous histiocytoma: an analysis of 40 cases examined by fine-needle aspiration cytology. Diagn Cytopathol 1986;2:46-54. 2. Meis-Kindblom JM, Bjerkehage...

... of pleomorphic morphology (previously pleomorphic malignant fibrous histiocytoma; MFH) usually occur in elderly adults. Morphologically, they can be either spindle cell, epithelioid, round cell, or pleomorphic (Fig. 1 ) (previous MFH). MFH was considered to be a distinct entity for many years [ 1...

... histiocytoma: classic, aneurysmal, and myxoid variants. Diagn Cytopathol 2004;31:387-391. 8. Frau DV, Erdas E, Caria P, Ambu R, Dettori T, Faa G, Fletcher CD, Vanni R: Deep fibrous histiocytoma with a clonal karyotypic alteration: molecular cytogenetic characterization of a t(16;17)(p13.3;q21.3). Cancer...

... metastatic malignancies from cutaneous primary sites include Merkel cell carcinoma, pleomorphic sarcoma (previously called malignant fibrous histiocytoma) and metastatic basal cell carcinoma. Systemic metastases can also occur from tumors such as renal cell carcinoma. This review will focus on the management...

..., Dal Cin P, Domanski HA: Angiomatoid fibrous histiocytoma a series of five cytologic cases with literature review and emphasis on diagnostic pitfalls. Diagn Cytopathol 2012;40(suppl 2):E86-E93. 9. Lemos MM, Karlen J, Tani E: Fine-needle aspiration cytology of angiomatoid malignant fibrous...

... been off-therapy for 5 and 18 months, respectively. Partial responses were seen in all other tumor types except for malignant fibrous histiocytoma and differentiated sarcomas, although in these categories inadequate numbers of patients were treated to conclude that ifosfamide is inactive. Toxicity...

...), respectively. The efficacy was measured in terms of growth delay (gd) of treated animals as compared to controls. IFO caused a statistically significant gd on a malignant fibrous histiocytoma (MFH), a leiomyo- and a neurofibrosarcoma xenograft (p < 0.05 each). These results were significant as well...

... atypical cells seen in smears from low-grade myxofibrosarcoma and low-grade fibromyxoid sarcoma. Angiomatoid Fibrous Histiocytoma Angiomatoid fibrous histiocytoma (AFH) is an indolent, rarely metastasizing neoplasm of uncertain lineage, commonly arising in the deep dermis and subcutaneous tissue...

... benign fibrous histiocytoma • Neurofibroma • Schwannoma • Nodular fasciitis • SFT • Other spindle-cell sarcomas arising in skin and subcutaneous tissue Cellular smears from DFSP are most often considered low-grade malignant spindle cell sarcoma. The most important differential...

... tracheal rings in an infant: endoscopic laser division and balloon dilation. J Pediatr Surg 2000;35:262-264 24. Conforti S, Bonacina E, Ravini M, Torre M: A case of fibrous histiocytoma of the trachea in an infant treated by endobronchial Nd:YAG laser. Lung Cancer 2007;57:112-114 25. Breen DP...

... granular cell tumor: role of laryngotracheal reconstruction. Int J Pediatr Otorhinolaryngol 2006;70:957-963 42. Conforti S, Bonacina E, Ravini M, Torre M: A case of fibrous histiocytoma of the trachea in an infant treated by endobronchial Nd:YAG laser. Lung Cancer 2007;57:112-114 43. Borasio P...

...: Malignant fibrous histiocytoma and atypical fibroxanthoma in renal transplant recipients. Dermatology 1999; 198: 29-32 75. Kovach BT Sams HH Stasko T: Multiple atypical fibroxanthomas in a cardiac transplant recipient. Dermatol Surg 2005; 31: 467-470 76. Swerdlow SH Webber SA Chadburn A Ferry...

...) in pericytic cells and GLUT1 in infantile hemangioma. Genetics No known recurrent or specific genetic changes have been described. Differential Diagnosis • Benign spindle-cell neoplasms • Angiomatoid fibrous histiocytoma • Malignant vascular neoplasms • Benign lipomatous tumors...

... (AFX), malignant fibrous histiocytoma and cutaneous leiomyosarcoma [ 73 - 75 ]. AFX manifests with a nodular lesion arising on sunexposed body regions, particularly the face and scalp, and clinically resembles BCC or SCC. Histologically, AFX is characterized by a dermal nodular proliferation of plump...

... in the “atypia” category in order to be histologically confirmed. Malignant Phyllodes Tumor versus Other Sarcomas Fibrosarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, and other rare sarcomas of the breast might be suspected in the presence of markedly atypical spindle cells in an aspirate...