Search Results for hippocampu

... Abstract The association between epilepsy and the hippocampus is well known and important. Mesial temporal epilepsy with hippocampal sclerosis is a syndromic diagnostic entity and indeed a quite common one. There are different theories on the pathophysiological pathways, as the hippocampus...

... Abstract There has been a long tradition in memory research of adopting the view of a vital role of the medial temporal lobe and especially the hippocampus in declarative memory. Despite the broad support for this notion, there is an ongoing debate about what computations are performed...

... Abstract AD is the commonest neurodegenerative disorder resulting ultimately in dementia, a stage during which there is a loss of previously acquired intellectual skill and independent occupational and social function. Neurodegenerative changes within the hippocampus and an extended neuronal...

... Abstract Stress hormones, i.e. cortisol in human and cortisone in rodents, influence a wide range of cognitive functions, including hippocampus-based declarative memory performance. Cortisol enhances memory consolidation, but impairs memory retrieval. In this context glucocorticoid receptor...

... Abstract The hippocampus is a temporal brain structure belonging to the limbic lobe and is fundamentally involved in memory processing, learning, and emotions. It consists of two allocortex laminae: the gyrus dentatus and the cornu ammonis, one rolled up inside the other, creating a bulge...

... Abstract The hippocampus expresses a variety of highly organized network states which bind its individual neurons into collective modes of activity. These patterns go along with characteristic oscillations of extracellular potential known as theta, gamma, and ripple oscillations. Such network...

... Abstract Developments in tasks and imaging techniques applied over the last decades have yielded substantial support for the hypothesized role of the hippocampus in mnemonic processes. Human imaging research has now moved on to disentangle the contributions of the different hippocampal...

... Abstract The human hippocampus is a highly complex structure located on the medial surface of the cerebral hemispheres as a part of the intralimbic gyrus. For clinical purposes, in addition to routine transverse MRI slices, acquisitions parallel and perpendicular to the long axis...

... models' of human diseases, as they will continue to need and benefit from a better understanding of the normal structure and functions of the hippocampus in ‘model animals'. Experimental studies conducted with animals are invaluable and remain to date irreplaceable, providing some...

... within the hippocampus, but also outside in both the subcortical and cortical areas. It is therefore of utmost importance to understand and always remember the anatomical and functional correlation of hippocampal abnormalities and deficits in both diseased and healthy ageing. These fascinating...

... Abstract The hippocampus is one of several brain regions that together comprise the hippocampal formation. The hippocampal formation is a prominent C-shaped structure bulging in the floor of the temporal horn of the lateral ventricle. The hippocampus proper consists of three major subfields...

... Abstract The role of the medial temporal lobe, specifically the hippocampus, in learning and memory has been consistently demonstrated over the past years and has led to the identification of the hippocampus as a target imaging marker for several neurological and psychiatric disorders...

..., a disturbance of venous hemodynamics) have been hypothesized. However, to date there is no scientific proof of any of these mechanisms. By using diffusion-weighted MRI 24-48 h after a TGA episode, small dot-like lesions have been detected in the hippocampus. This has led to the implication that the selective...

... amnesia as the sole or primary manifestation of acute - mostly left-sided - hippocampal stroke was described. With the use of modern MRI techniques the identification of typical ischemic stroke lesion patterns affecting the hippocampus has become possible. Although overt cognitive deficits in unilateral...