Search Results for high

... developed 20 MHz high-intensity focused ultrasound (HIFU) is introduced as a complementary method to lasers, but also as a stand-alone treatment for selected groups. 20 MHz HIFU allows for application of high-power ultrasound energy to very small focal targets in the dermis, and thereby precise confinement...

... spectrophotometers. This research evaluated the protection of 10 high-SPF (30–110), broad-spectrum sunscreen products, as well as 6 sun-protective fabrics against natural sunlight in Arequipa, Peru. Each of the 17 subjects was exposed to natural sunlight for 1 h and 59 min under clear skies, with temperatures...

... Abstract Videostroboscopy and high-speed imaging is now an accepted way to evaluate laryngeal function in patients with voice disorders. In patients with neurolaryngological diseases such as tremor, laryngeal spasm, and paralysis, having an objective way to evaluate vocal function is desirable...

... Abstract Since the first successful use of high-frequency electrical stimulation of trigeminal branches for treatment of facial pain in 1962, neuromodulation techniques become well established but remain greatly underutilised. Most subsequent implantation techniques and commercial devices...

... and the palliation of bone metastasis. It is in the brain though, where therapeutic ultrasound arguably holds the most promising possibilities, including neuromodulation, focused ultrasound surgery, and blood-brain barrier (BBB) disruption. Recent clinical trials of MRI-guided high-intensity focused ultrasound (HIFU...

... Abstract Multiple phase II clinical trials on the use of tumor vaccines in cases of high-grade gliomas (HGG), in particular autologous formalin-fixed tumor vaccine (AFTV), demonstrated the safety and potential efficacy of such therapy. There is evidence that maximal resection of neoplasm...

...-loaded polymers. Many of these therapeutic approaches have shown promising results in management of high-grade gliomas. Introduction High-grade gliomas (HGG) are intrinsically invasive and resistant to many forms of treatment. Current management options for such tumors include a combination...

... among disadvantaged populations, they also present a public health problem in some industrialized countries. Vitamin D deficiency is a good example, as it is certainly prevalent in some upper-middle to high-income countries, arising due to a lack of ultraviolet B (UVB) sunshine availability for anything...

... demonstrated the efficacy of specific drugs in subsets of patients with high-grade astrocytomas that has revived the enthusiasm for the role of systemic chemotherapy against these neoplasms. Temozolomide, a monofunctional alkylator, was the first chemotherapeutic agent to definitively improve survival...

.... Introduction High-grade gliomas (HGG) including glioblastoma multiforme (GBM) of the World Health Organization (WHO) histopathological grade IV and other anaplastic tumors of WHO grade III, account for approximately 80% of adult primary malignant brain neoplasms diagnosed in the United States each year...

... several neurological disorders. The results that have been reported thus far suggest that MRgFUS achieves a high success rate with a very low rate of permanent complications. To achieve successful transcranial sonication, significant limitations associated with delivering energy through the skull had...

... of large families for successful positional cloning. Major technological advancements in the past decade have empowered high-throughput next-generation sequencing approaches that have already facilitated the recognition of over 30 genes since 2010 and shifted hurdles away from achieving economical and time...

... during infancy, which is associated with higher risk of obesity during childhood and adult life. This can have lifelong consequences such as increased risk of noncommunicable diseases. Many studies indicate that infants of obese and nonobese mothers who were fed traditional (high-protein) formulas gain...

... disorders. Of the 639 individuals so far assessed in the Bruderholz Early Psychosis Outpatient Service for Adolescents and Young Adults, 230 (36%) met ultra-high-risk criteria, 206 (89.6%) of whom suffered from one of the five symptom groups mentioned above. The present chapter highlights that with a purely...

... of treatment. Preventative interventions in several arenas of medicine have advanced, but have only come to the fore in psychiatry in the last two decades. It was long known that a preclinical phase preceded psychosis, now commonly termed as ‘ultra-high-risk (UHR)' status. The advent of specialized early...

... Abstract Neuroblastoma is a heterogeneous tumor that displays several numerical and structural copy number variations. Metastatic tumors of high-risk patients frequently show loss of chromosomes 1p, 4p, 9p, 11q and 14q, and gains of chromosomes 2p, 12p and 17q. Moreover, tumor tissue gene...

... Abstract This chapter focuses on endeavors to perform keratoplasties to treat eyes in high-risk settings and discusses alternative approaches (such as lamellar strategies). The historical and molecular backgrounds (histocompatibility antigens) as well as associated risk factors (corneal...