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Series: Current Problems in Dermatology
Volume: 56
Published: 05 July 2023
10.1159/000521487
EISBN: 978-3-318-07040-8
... developed 20 MHz high-intensity focused ultrasound (HIFU) is introduced as a complementary method to lasers, but also as a stand-alone treatment for selected groups. 20 MHz HIFU allows for application of high-power ultrasound energy to very small focal targets in the dermis, and thereby precise confinement...
Book Chapter
Series: Current Problems in Dermatology
Volume: 55
Published: 29 November 2021
10.1159/000517666
EISBN: 978-3-318-06608-1
... spectrophotometers. This research evaluated the protection of 10 high-SPF (30–110), broad-spectrum sunscreen products, as well as 6 sun-protective fabrics against natural sunlight in Arequipa, Peru. Each of the 17 subjects was exposed to natural sunlight for 1 h and 59 min under clear skies, with temperatures...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 85
Published: 18 December 2020
10.1159/000456681
EISBN: 978-3-318-06628-9
... Abstract Videostroboscopy and high-speed imaging is now an accepted way to evaluate laryngeal function in patients with voice disorders. In patients with neurolaryngological diseases such as tremor, laryngeal spasm, and paralysis, having an objective way to evaluate vocal function is desirable...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 35
Published: 18 December 2020
10.1159/000509665
EISBN: 978-3-318-06795-8
... Abstract Since the first successful use of high-frequency electrical stimulation of trigeminal branches for treatment of facial pain in 1962, neuromodulation techniques become well established but remain greatly underutilised. Most subsequent implantation techniques and commercial devices...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 32
Published: 23 July 2018
10.1159/000469678
EISBN: 978-3-318-06063-8
... and the palliation of bone metastasis. It is in the brain though, where therapeutic ultrasound arguably holds the most promising possibilities, including neuromodulation, focused ultrasound surgery, and blood-brain barrier (BBB) disruption. Recent clinical trials of MRI-guided high-intensity focused ultrasound (HIFU...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 32
Published: 23 July 2018
10.1159/000469684
EISBN: 978-3-318-06063-8
... Abstract Multiple phase II clinical trials on the use of tumor vaccines in cases of high-grade gliomas (HGG), in particular autologous formalin-fixed tumor vaccine (AFTV), demonstrated the safety and potential efficacy of such therapy. There is evidence that maximal resection of neoplasm...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 32
Published: 23 July 2018
10.1159/000469688
EISBN: 978-3-318-06063-8
...-loaded polymers. Many of these therapeutic approaches have shown promising results in management of high-grade gliomas. Introduction High-grade gliomas (HGG) are intrinsically invasive and resistant to many forms of treatment. Current management options for such tumors include a combination...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 118
Published: 24 April 2018
10.1159/000484391
EISBN: 978-3-318-06253-3
... among disadvantaged populations, they also present a public health problem in some industrialized countries. Vitamin D deficiency is a good example, as it is certainly prevalent in some upper-middle to high-income countries, arising due to a lack of ultraviolet B (UVB) sunshine availability for anything...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 31
Published: 06 February 2018
10.1159/000467374
EISBN: 978-3-318-06059-1
... demonstrated the efficacy of specific drugs in subsets of patients with high-grade astrocytomas that has revived the enthusiasm for the role of systemic chemotherapy against these neoplasms. Temozolomide, a monofunctional alkylator, was the first chemotherapeutic agent to definitively improve survival...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 31
Published: 06 February 2018
10.1159/000467379
EISBN: 978-3-318-06059-1
.... Introduction High-grade gliomas (HGG) including glioblastoma multiforme (GBM) of the World Health Organization (WHO) histopathological grade IV and other anaplastic tumors of WHO grade III, account for approximately 80% of adult primary malignant brain neoplasms diagnosed in the United States each year...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 33
Published: 22 January 2018
10.1159/000481080
EISBN: 978-3-318-06202-1
... several neurological disorders. The results that have been reported thus far suggest that MRgFUS achieves a high success rate with a very low rate of permanent complications. To achieve successful transcranial sonication, significant limitations associated with delivering energy through the skull had...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444599
EISBN: 978-3-318-05856-7
... of large families for successful positional cloning. Major technological advancements in the past decade have empowered high-throughput next-generation sequencing approaches that have already facilitated the recognition of over 30 genes since 2010 and shifted hurdles away from achieving economical and time...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 85
Published: 25 April 2016
10.1159/000439492
EISBN: 978-3-318-05643-3
... during infancy, which is associated with higher risk of obesity during childhood and adult life. This can have lifelong consequences such as increased risk of noncommunicable diseases. Many studies indicate that infants of obese and nonobese mothers who were fed traditional (high-protein) formulas gain...
Book Chapter
Series: Key Issues in Mental Health
Volume: 181
Published: 15 January 2016
10.1159/000440913
EISBN: 978-3-318-05621-1
... disorders. Of the 639 individuals so far assessed in the Bruderholz Early Psychosis Outpatient Service for Adolescents and Young Adults, 230 (36%) met ultra-high-risk criteria, 206 (89.6%) of whom suffered from one of the five symptom groups mentioned above. The present chapter highlights that with a purely...
Book Chapter
Series: Key Issues in Mental Health
Volume: 181
Published: 15 January 2016
10.1159/000440914
EISBN: 978-3-318-05621-1
... of treatment. Preventative interventions in several arenas of medicine have advanced, but have only come to the fore in psychiatry in the last two decades. It was long known that a preclinical phase preceded psychosis, now commonly termed as ‘ultra-high-risk (UHR)' status. The advent of specialized early...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 20
Published: 28 September 2015
10.1159/000382066
EISBN: 978-3-318-05497-2
... Abstract Neuroblastoma is a heterogeneous tumor that displays several numerical and structural copy number variations. Metastatic tumors of high-risk patients frequently show loss of chromosomes 1p, 4p, 9p, 11q and 14q, and gains of chromosomes 2p, 12p and 17q. Moreover, tumor tissue gene...
Book Chapter
Book: Cornea
Series: ESASO Course Series
Volume: 6
Published: 11 August 2015
10.1159/000381494
EISBN: 978-3-318-05453-8
... Abstract This chapter focuses on endeavors to perform keratoplasties to treat eyes in high-risk settings and discusses alternative approaches (such as lamellar strategies). The historical and molecular backgrounds (histocompatibility antigens) as well as associated risk factors (corneal...