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Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444568
EISBN: 978-3-318-05856-7
... Abstract There has been considerable progress in identifying the mutations primarily associated with congenital hearing loss caused by a single gene. The next challenge is the discovery of genes and mutations associated with common acquired hearing loss in the human population such as age...
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Book Cover Image
Published: 31 December 1953
10.1159/isbn.978-3-318-04267-2
EISBN: 978-3-318-04267-2
Book
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/000485587
EISBN: 978-3-318-06315-8
... Abstract The number of marketed bone-conduction hearing implants (BCHIs) has been steadily growing, with multiple percutaneous devices and transcutaneous devices now available. However, studies assessing efficacy often have small sample sizes and employ different assessment methodologies. Thus...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/000485525
EISBN: 978-3-318-06315-8
... Abstract Microtia and atresia cause significant conductive hearing loss of up to 60 dB HL. The bilateral cases suffer from severely restricted communication abilities and require immediate acoustic stimulation. There is also growing evidence that unilateral cases benefit from an early...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/000485529
EISBN: 978-3-318-06315-8
... Abstract Hearing implant technology is evolving at a rapid rate and more than ever patients with hearing loss are benefiting from these emerging hearing devices. Active middle ear implants are alternatives to hearing aids and bone conducting devices, offering patients an expanded range...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/000485544
EISBN: 978-3-318-06315-8
... Abstract Cochlear implantation (CI), with attempted preservation of residual natural low-frequency hearing, is an increasingly accepted application of this technology, with potential benefits to the patient when listening in noise and in music appreciation. The full extent of the benefits...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/000485526
EISBN: 978-3-318-06315-8
... Abstract Bilateral vestibular schwannomas are almost pathognomonic of neurofibromatosis type 2 (NF2). As a result of these tumors, hearing loss is the presenting symptom in 60% of adults and 30% of children with NF2. It is often bilateral. The best means of preserving hearing in patients...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/000485541
EISBN: 978-3-318-06315-8
... Abstract Surgery aimed at hearing rehabilitation risks damaging residual inner ear function, especially cochlear implant surgery. Pharmacological intervention to reduce this risk has shown great promise in animal models. The challenge is to deliver medication to the appropriate part...
Book
Book Cover Image
Series: Advances in Oto-Rhino-Laryngology
Volume: 81
Published: 07 May 2018
10.1159/isbn.978-3-318-06315-8
EISBN: 978-3-318-06315-8
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444561
EISBN: 978-3-318-05856-7
... Abstract Relationships are central to social well-being and emotional resilience across the lifespan, and good hearing and communication is integral to their establishment and maintenance. However, hearing loss is one of the most prevalent chronic conditions of ageing and significantly affects...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444598
EISBN: 978-3-318-05856-7
... Abstract Hearing loss is the most common sensory deficit in humans. Untreated hearing loss will affect speech and language development and lead to impaired cognitive and social skills. Early detection and intervention have proven critical to successful rehabilitation and help individuals...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444564
EISBN: 978-3-318-05856-7
... the diagnostic evaluation of patients with hearing loss, considering the audiological, radiological and clinical aspects. Background Communicatively significant permanent hearing loss affects up to 1-3:1,000 newborns, with 50-60% of cases estimated to result from genetic etiologies [ 1 ]. Infectious...
Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444599
EISBN: 978-3-318-05856-7
... Abstract Hereditary hearing loss is a classic genetically heterogeneous condition with nearly 100 nonsyndromic hearing loss genes currently described and many more awaiting discovery. Priorities in the field with potentially rapid clinical application are the identification of all genes...