... Abstract The formation of the dental enamel is a consequence of a complex series of events and when disturbed, visible consequences ranging from hypoplasia to hypomineralization occur. Less dramatic alterations of the enamel structure and conformation are argued to modulate individual...

... activity, facilitating bolus formation, and taste. It contains proteins, such as histatins and acidic proline-rich, which are present only in saliva, proteins that are present in several different body fluids aside from saliva, such as lysozyme, mucins, and immunoglobulins, and proteins not originating...

... activity was highest at pH 8, whereas mass had the highest value at pH 7. In conclusion, the initial pH value influences biofilm formation. In particular, metabolic activity and the amount of bacteria associated with disease correlated with the respective pH known to be of importance in the development...

... formation. A microbroth dilution technique was used to determine the minimum inhibitory concentration of the substances against two laboratory strains and seven clinical isolates. Furthermore, a potential inhibition of biofilm formation of C. albicans or C. glabrata (single-species biofilm or mixed...

... conditions (strictures or irritable bowel). In the present chapter, we will focus on immunogenicity, which is the capacity of the foreign biologic to produce an immune response within the human body. Formation of Neutralizing Antibodies Biologics are nonnative proteins manufactured from exogenous...

... Abstract The hippocampus is one of several brain regions that together comprise the hippocampal formation. The hippocampal formation is a prominent C-shaped structure bulging in the floor of the temporal horn of the lateral ventricle. The hippocampus proper consists of three major subfields...

... in conventionally fed animals, suggesting the importance of feeding in the formation of intestinal lesions. Furthermore, it appears that insoluble dietary fibers such as cellulose in the diet play an important role in the formation of NSAID-induced intestinal lesions, whereas soluble dietary fibers such as pectin...

... structure are of great research interest. Histological studies show that lumen formation begins during the mid stages of branching morphogenesis. At this stage, apoptotic cells are detectable in the developing salivary ducts at sites where lumina are forming, suggesting that programmed cell death...

... oxidative attacks in the course of antioxidative action. We investigated the formation of CBPs by stimulated neutrophils (and at further conditions), tested the hypothesis that CBPs may exert mitochondriotoxicity and tried to prevent toxicity in the presence of members of the antioxidative network...

... Abstract The key mechanisms controlling where and when craniofacial bones and hence suturesform are discussed in this review. These include the formation and growth of skeletogeniccondensations, tissue to tissue interactions between the epithelium, skeletogenic mesenchymeand the underlying...

... Abstract This chapter reviews the cellular and molecular componentsthat lead to delayed-type hypersensitivity granuloma formationduring interstitial lung diseases. Granuloma formation is comprisedof four main steps: (1) the triggering of T cells by antigenpresentingcells, represented...

... subsequent recognition by naturallyoccurringantibodies, experimental approaches that diminish or prevent formation of largeimmunostimulatory IC should be further explored. ...

... aberrancy exposes N-acetylgalactosamine-containing neoepitopes recognized by naturallyoccurring IgG or IgA1 antibodies resulting in formation of immune complexes. IgA1 containsup to six O-glycosylation sites per heavy chain; it is not known whether the glycosylation defectoccurs randomly or preferentially...

... Abstract The immune surveillance theory proposed almost half a century ago stated that theimmune system was responsible for preventing the formation of spontaneous tumors by identifyingand eliminating neoplastic cells early in their development. Recent studies demonstratingthat innate...