... Abstract Diabetes, a major public health concern, is increasing in prevalence worldwide. A diabetic patient has an up to 25% lifetime risk of developing a foot ulcer condition that predisposes that patient to lower-extremity amputation. The underlying pathology is diabetic peripheral neuropathy...

... failed to relieve her symptoms. Radiographs of her foot revealed a healed Chevron osteotomy and a short first metatarsal. On the lateral radiograph, the structure of the foot was defined as a subtle cavus foot ( Figs. 1 and 2 ). The indication for Barouk-Rippstein-Toullec (BRT) osteotomies of the three...

... were used to correct the right foot and ankle in the same surgical time ( Fig. 2 ). The left foot and ankle underwent a tibiotalar arthrodesis, M1 closed wedge osteotomy (fixated with two cannulated 3-mm screws), and transfer of the posterior tibial tendon to the dorsum of the foot to prevent...

.... Diabetic foot disorders are common throughout the world, resulting in major medical, social and economic consequences for the patients, and a public health problem. The risk for ulceration and amputation is much higher in individuals with diabetes compared to that of the non-diabetic population...

... Abstract Diabetic foot syndrome (DFS) is considered the most severe and complicated framework of 2 diabetes-related long-term complications, peripheral neuropathy and peripheral arterial disease, and foot ulceration is usually their main clinical expression. Due to the presence of several co...

... Abstract The diabetic foot syndrome represents a relatively recent field of scientific interest: since the beginning the double origin of the disease has been evident: neuropathy and arteriopathy act together. In such a complex disease, the need for a “clinic” approach by a multidisciplinary...

... Abstract Charcot neuropathic osteoarthropathy (CN) is one of the most debilitating complications of diabetic neuropathy. It classically presents as a red hot swollen foot, precipitated by trauma. The latter leads to fracture, bone fragmentation and ultimately foot deformity. Recent advances...

... damages probably through a common pathway represented by increased intracellular oxidative stress. Among diabetic chronic complications, the pathology related to diabetic foot plays a major role and is the most common reason for hospitalization in diabetic patients. Nearly all components of the lower...

... Abstract The diabetic foot (DF) is a progressive and destructive complication of diabetes mellitus. It has a multifaceted pathogenesis and a complex clinical course, with different phases and patterns, so much so that it is befitting to define it more as the “DF syndrome.” The problems...

... Abstract When there is loss of protective sensation, elevated plantar pressure is a causative factor in the development of plantar foot ulcers in persons with diabetes. Therefore, to prevent and heal these foot ulcers, offloading is an important aspect of treatment. Neuropathic plantar forefoot...

... osteoarthropathy (CN) involving the foot and/or the ankle is a challenging clinical condition that causes progressive bone deformity and osteoarticular instability, which leads to ulcerations, spread of infection and, consequently, an elevated risk of amputation [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ]. CN does not only...

... Abstract Critical limb ischaemia is frequently associated to diabetic foot ulcers, and its recognition and timely treatment are crucial to achieve ulcer remission. Lower limb atherosclerosis in diabetic patients is characterized by having an earlier onset, a more aggressive pattern, a higher...

... Abstract Non-communicable diseases became the leading cause of global mortality almost a decade ago and the epidemic of diabetes is one of its major contributors. Diabetes affects more than 415 million people across the world and the diabetic foot ulcer (DFU) is one of its prime manifestations...

... Abstract In a world where both the prevalence of diabetes and resistance to antibacterial drugs are rapidly increasing, the emerging diabetic foot infection (DFI), which is caused by resistant and multi-resistant strains, is considered an emergency situation both from a clinical and from...

... Abstract Diabetic foot infections (DFIs) are very frequent conditions that lead to the prescription of antibiotics. Skin and soft tissue infections are distinct with regard to the management of osteomyelitis but are seen concomitantly in a high proportion of patients. The propensity...

... Abstract Surgery is frequently required to treat diabetic foot infections (DFIs) as part of the comprehensive approach of providing treatment to the patient. The goal is to evacuate pus, remove necrotic tissue and minimize the risk for further spread, thereby creating a good wound bed...

... Abstract The outcome of ulcers of the foot in diabetes is generally poor with prolonged healing times and a marked increase in the risk of amputation compared with patients without diabetes. There is therefore an urgent need for the development of interventions to improve outcomes. The evidence...

... Abstract Management of the diabetic foot is multifaceted and requires constant monitoring from patients and health care providers. The alarmingly high rates of diabetic foot ulcer recurrence are an indication for a change that we need to bring about in our approach to care and to the use...