... Abstract This chapter presents an overview of different addictive and obsessive-compulsive symptoms and their constellations due to focal brain lesions. In general, such symptoms are not systematically reported in the literature, and the knowledge about the networks involved is sometimes sparse...

... Abstract Background: Clinical observations of rapid proteinuria after kidney transplantation suggest the existence of a causative permeability factor in the circulation of focal segmental glomerulosclerosis (FSGS) patients. Searching for such factor(s) however has been extremely painstaking...

... Abstract Various drugs have been used for the treatment of focal segmental glomerular sclerosis (FSGS) or minimal change disease (idiopathic nephrotic syndrome, INS) including methylprednisolone pulses, alkylating agents and calcineurin inhibitors, often without a strong rationale. For some...

... Abstract Objectives: Familial focal segmental glomerulosclerosis (FSGS) has been widely reported as having an underlining genetic component to its pathogenesis. Recently, mutations in TRPC6 and ACTN4 were identified to be associated with familial FSGS, however few studies have reported...

... Abstract Objective: Focal segmental glomerular sclerosis (FSGS) is one of the most important causes of end-stage renal disease (ESRD). The pathogenesis, clinical manifestation, pathological changes and treatment of FSGS differ in patients with and without a family history of the disease...

... Abstract This study aimed to analyze the treatment, clinical outcomes, and risk factors that affect the prognosis of patients with primary focal segmental glomerulosclerosis (FSGS) and to provide theoretical evidence for various treatment options in these patients. The study reviewed...

... Abstract One of the major advances in the care of patients with congenital hyperinsulinism was the discovery of focal adenomatous hyperplasia since patients can be definitively cured after a limited pancreatectomy. The histological features include hyperplasia and an increased beta-cell mass...

... Abstract Approximately half of the infants with congenital hyperinsulinism who require surgical pancreatectomy for glucose control have a potentially curable focal lesion. Molecular imaging with [ 18 F]-l-3,4-dihydroxyphenylalanine ([ 18 F]-DOPA) PET has revolutionized the diagnostic evaluation...

... Abstract Tonsillar focal disease is defined as clinical disorders in the distant organ from the tonsil that are caused by the tonsils without any symptoms of the tonsil itself. Palmoplantar pustulosis and IgA nephropathy are known typical tonsillar focal diseases. In this paper, the clinical...

... tonsillectomy. Arthritis ceased after the treatments and no recurrence was found. Discussion : Sterile inflammatory arthritis induced by tonsillitis was cured by resection of the microabscess in the tonsils. Therefore, ReA induced by tonsillitis is one form of ‘focal infection’. Reactive arthritis (ReA...

... Abstract Some inflammatory skin diseases are known to be related to tonsil focal infection at their onset. Administration of antibiotics is adequate treatment in most acute or subacute cases. However, chronic focal infections in the tonsils could cause chronic skin diseases like pustulosis...

... is a representative skin disorder showing a close relationship with focal infections such as tonsillitis, chronic sinusitis, and dental infection. In particular, tonsillitis often triggers or deteriorates PPP. In Japanese patients, regions other than the palms and soles are occasionally affected manifesting scaly...

..., a piano work which allowed high level virtuosoperformance without the use of the middle finger of the right hand. However, from1833, he almost completely gave up playing piano literature, but continued to improvise.Robert Schumann was suffering from a focal, task specific dystonia of the right hand...