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filarial

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Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104231
EISBN: 978-3-318-01399-3
... Abstract Filarial worm infections of humans cause morbidity and even death in developingcountries of the tropics. Current antifilarial drug therapies target only the first-stage larvae,requiring many years of annual/biannual treatment. Another problem with controlling filarialinfections...
Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104233
EISBN: 978-3-318-01399-3
... Abstract Wolbachia of arthropods and nematodes have contrasting patterns of association withtheir hosts. These patterns reflect the biological nature of the associations: parasitic in arthropodsand possibly mutualistic in filarial nematodes. Genome sequence data are aiding in boththe resolution...
Book Chapter
Book Chapter
Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104228
EISBN: 978-3-318-01399-3
... endosymbionts required for survival of their hosts and embryogenesis of microfilariae,are present in all larval stages during the life cycle of filarial, and contribute to someof the inflammatory responses and pathological manifestations of filarial infections in thevertebrate hosts. Susceptibility of Wolbachia...
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Book Cover Image
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/isbn.978-3-318-01399-3
EISBN: 978-3-318-01399-3
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 92
Published: 24 January 2007
10.1159/000099276
EISBN: 978-3-318-01404-4
... Abstract Chronic infection with filarial nematodes results in development of a suppressiveresponse to an immense parasite burden, thereby limiting pathological and clinical manifestations.However, pro-inflammatory responses to dead and degenerating Onchocercavolvulus worms and release...
Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104403
EISBN: 978-3-318-01399-3
... Abstract Filarial worms are generally of little veterinary importance, with the exception ofDirofilaria immitis, the agent of canine and feline heartworm disease. Another filarial nematode,Onchocerca ochengi, causes subcutaneous filariasis in cattle and has become anincreasingly important...
Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104404
EISBN: 978-3-318-01399-3
... Abstract Over 150 million individuals worldwide are infected with filarial nematodes, whichinclude Wuchereria bancrofti and Brugia malayi that cause lymphatic filariasis, andOnchocerca volvulus, which causes onchocerciasis (river blindness). These nematodes all harborendosymbiotic Wolbachia...
Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104230
EISBN: 978-3-318-01399-3
... Abstract Our knowledge of the symbiosis between Wolbachia and filarial nematodes has grownrapidly in recent years. Phylogenetic analyses, which highlight a coevolutionary pattern forfilarial nematodes and their wolbachiae, and molecular evolutionary analyses, showing noevidence for positive...
Book Chapter
Series: Issues in Infectious Diseases
Volume: 5
Published: 25 June 2007
10.1159/000104232
EISBN: 978-3-318-01399-3
... on a single drug therapy for onchocerciasis for which there is evidence ofresistance. Wolbachia are attractive targets for control of filariasis as the endosymbiontsappear to be obligate for human filarial nematode vitality. Antibiotic studies in both animalmodels and in human trials indicate that disruption...
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Series: Progress in Respiratory Research
Volume: 7
Published: 05 November 1974
10.1159/isbn.978-3-318-04110-1
EISBN: 978-3-318-04110-1
Book
Series: Chemical Immunology and Allergy
Volume: 66
Published: 12 March 1997
10.1159/isbn.978-3-318-00224-9
EISBN: 978-3-318-00224-9
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Published: 22 February 1989
10.1159/isbn.978-3-318-05073-8
EISBN: 978-3-318-05073-8
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 100
Published: 27 May 2014
10.1159/000358860
EISBN: 978-3-318-02195-0
... with mite tropomyosins. IgE reactivity to this allergen is very frequent in both asthmatic and normal subjects sensitized to Ascaris [ 40 ]. Filarial and mite tropomyosins are similar, with a 72% identity at the amino acid level and overlapping predicted 3D structures. Filarial infection induces strong...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 43
Published: 04 May 2020
EISBN: 978-3-318-06678-4
... Immunopathol 2012;34:889–901. 70. Berbudi A, Surendar J, Ajendra J, Gondorf F, Schmidt D, Neumann AL, et al: Filarial infection or antigen administration improves glucose tolerance in diet-induced obese mice. J Innate Immun 2016;8:601–616. 71. Lumeng CN, Bodzin JL, Saltiel AR: Obesity induces...
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Series: Chemical Immunology and Allergy
Volume: 90
Published: 02 January 2006
10.1159/isbn.978-3-318-01251-4
EISBN: 978-3-318-01251-4
Book
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Published: 05 March 1996
10.1159/isbn.978-3-318-05151-3
EISBN: 978-3-318-05151-3
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
10.1159/000323290
EISBN: 978-3-8055-9687-9
... settings through the development of parasite-derived drugs [ 121 ]. An example of such a target molecule is ES-62, a glycoprotein secreted by filarial worms that is able to inhibit mast cell degranulation, but clinical studies are still awaited [ 122 ]. Once our immune systems have lost balance...
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Series: Progress in Tumor Research
Volume: 38
Published: 07 March 2005
10.1159/isbn.978-3-318-01198-2
EISBN: 978-3-318-01198-2