... and Triton Swept-Source OCT of the posterior pole and mid-periphery. When considered necessary, fluorescein fundus angiography (FFA) with OPTOS California wide-field imaging was performed. The findings were compared with the current literature. Results: Forty-three consecutive patients (86 eyes) were...

... and can have grave consequences on the action of insulin on glucose uptake. In healthy muscle, glucose and free fatty acids (FFAs) are efficiently metabolized preventing the accumulation of harmful lipid by-products. In contrast, in pre-diabetic conditions, reduced oxidative capacity, high levels...

...), cholesterol (CHOL) and free fatty acids (FFAs). These lipid classes are present in an approximately equal molar ratio [ 19 ]. We will first describe the most important observations reported until now. FFAs consist of a single carbon chain with a variation in chain length in human SC between around 14...

... laboratory situation. Higher increments of FFA, cholesterol, BG, BP and HR were recorded in the CHD group. No differences in the strength of emotion and personality traits -considering Leary’s and Eysenck’s inventories–were found. Higher levels of cholesterol or its increments were ascertained in CHD...

... insulin-mediated inhibition of basal lipolysis. Together with increased body fat mass, this contributes to an increase in the level of circulating free fatty acids (FFAs). FFAs are in turn causally related to insulin resistance and reactive hyperinsulinemia in three different ways. FFAs reduce insulin...

... variants include classic LPP, frontal fibrosing alopecia (FFA), and Graham-Little syndrome. Pathogenesis The pathogenesis of LPP remains to be fully elucidated, but like other cicatricial alopecias, it involves the irreversible destruction of hair follicle stem cells and the loss of the capacity...

... equivalent for the physical barrier function of the stratum corneum (SC) [ 1 , 2 , 3 ]. Of the SCs total mass, 10 up to 15% are lipids, subdivided approximately into 40% ceramides, 25% cholesterol, 25% free fatty acids (FFA), 5% cholesterol sulphate and less than 1% triglycerides [ 4 , 5 ]. The backbone...

... in storing triglycerides which provide energy in the form of free fatty acids (FFA), and the released FFA may contribute to insulin resistance in peripheral tissues. Therefore, it was plausible to hypothesize that resistin might represent a link between increased FFA plasma levels and insulin resistance...

... ). Fig. 1 Multimodal imaging pictures of right eye type 1 CNV. a FFA shows late leakage from an undetermined source (black arrow) as occult CNV pattern. b ICGA shows the actual CNV (white arrow). c Infrared imaging showing OCT scan orientation and direction. d OCT B-scan reveals parafoveal sub...

... is determined. SC lipids ceramides (CER; Ceramide EOS = Ceramide 1 = N-Acetylsphingosine, Ceramide NP = Ceramide 3 = N-Acyl-Phytoshingosin, Ceramide NH = Ceramide 6 = Ceramide 6 II), free fatty acids (FFA; palmitic acid, stearic acid, linoleic acid, linolenic acid, oleic acid) and cholesterol (CHOL...

... the levels of free fatty acids (FFA), IGF-I, ketone bodies, insulin and glucose. Conversely, fasting and stress increase GH secretion, whereas feeding inhibits it, suggesting a predominant role for GH in fasting conditions or in the postabsorptive states [ 1 , 4 ]. Then, GH actions on glucose metabolism...

... to transplant sufficient grafts (up to 2,500 grafts). These differences makes it possible to use PL-FUT to treat patients with AGA, facial and scalp burns or progressive scarring alopecias, such as FFA, as well as for the restoration of eyebrows. PL-FUT has great advantages over traditional hair...

... ], retinal cells [ 21 ] and human monocytes [ 22 ]. Moderately elevated glucose concentrations (11 m M ) were sufficient to induce transcriptional activation of IL-1β expression in human islets [ 14 ]. More recently, it was also found that long-chain free fatty acids (FFAs) induce several cyto...

... as the balance of the microbial flora [ 5 ] depend on the acidic skin surface pH. Numerous endogenous pathways contribute to the acidic skin surface pH: (I) Proton-donating free fatty acids (FFA) generated from the hydrolysis of epidermal phospholipids and other complex lipids in the late stages...

... to a ‘portal’ effect of greater free fatty acids (FFA) and glycerol release with proximal access to the liver [ 20 ]. This hypothesis had remained attractive for many years since obesity is associated with higher FFA levels and excess circulating FFA are known to promote insulin resistance in skeletal muscle...

... for the development of hypoglycemia, low glycogen stores, delayed oxidation of FFA and induction of PEP-CK [ 17 , 18 ]. Hypocalcemia may occur due to excess phosphate release from damaged cells or acidosis, but is not a consistent feature of SGA per se unless accompanied by prematurity. Fasting hypoglycemia...

... in muscle and fat [ 8 , 9 ]. Being a fundamentally lipolytic hormone, GH increases free fatty acids (FFAs), which themselves suppress glucose transporters in muscle and adipose tissue [ 3 , 7 ]. At least in the early stages of the disease, patients with acromegaly maintain a normal fasting glucose...

...) on adipocytes that induces NF-κB signaling pathway activation. The TNF-induced NF-κB activation in adipocytes results in increased lipolysis with release from adipocytes of free fatty acids (FFA). These FFA act as paracrine TLR4 ligands that induce NF-κB signaling pathway activation inside macrophages...