... within the otosclerotic focus. Stapes footplates from 30 patientswith clinical otosclerosis undergoing stapedectomy were formalin fixed, decalcified andparaffin embedded. As controls, 30 autoptic temporal bone specimens were employed. Weinvestigated the expression of collagens I-V...

... Abstract Premature development of breast and/or pubic hair in a prepubertal girl used to raise questions and concerns from the families. There is actually a wide range of clinical expressions of precocious puberty in girls and not all presentations are considered to be true precocious puberty...

... Abstract Gap junctions, assembled from connexins, form the cell-to-cell pathways for propagationof the precisely orchestrated patterns of current flow that govern the synchronized rhythm ofthe healthy heart. As in most tissues and organs, multiple connexin types are co-expressed inthe heart...

... summarizes results of gene expression profiling of allergic disease and immunologicallyrelevant cells, using DNA array technology. The results of these studies are searchablein public databases and represent exciting tools to study gene expression of diseases on aglobal base. ...

... of expression andthe signals that modulate CFTR expression can provide criticalinsights into the pathogenesis of CF and the functions ofCFTR.Also, understanding the regulation of endogenous CFTRexpression is fundamental to the development of appropriateand specific gene therapy for CF and the possibility...

... described to be expressed by human mast cells of differentorigins. Seven chemokines (CXCL1, CXCL5, CXCL8, CXCL14, CX3CL1, CCL5and CCL11) have been shown to act on some of these receptors and to induce mast cellmigration. Mast cells have a unique expression pattern of CCR3, CXCR1 and CXCR2.These receptors...