... by an excess of unbound unconjugated bilirubin (UUB) in the plasma. The pathogenesis involves albumin binding and free bilirubin plasmatic levels, passage across the blood-brain barrier, and neuronal susceptibility to injury. Phototherapy and, eventually, exchange transfusion remain the primary treatment...

... Abstract Plasma exchange (PE) therapy is the most commonly used treatment in Japan today. The issue with PE is that it removes coagulation factors and other essential molecules during the treatment process. Fresh frozen plasma (FFP) is used to replace the essential molecules which are lost...

... and EUBIROD. The conclusions underpin the importance to follow up all recent experiences concluded positively, with consistent initiatives aimed at engaging governments, health professionals, and the whole community in the safe exchange of diabetes information, which is in everyone's interest...

... Abstract Plasma exchange has been used for the treatment of rapidly progressive glomerulonephritis (RPGN) for more than 40 years. Its main application has been the rapid removal of special pathogenic factors that are of great importance for treatment of antiglomerular basement membrane disease...