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Book Cover Image
Series: Frontiers of Hormone Research
Volume: 55
Published: 01 August 2024
10.1159/isbn.978-3-318-07354-6
EISBN: 978-3-318-07354-6
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
10.1159/000516733
EISBN: 978-3-318-06296-0
... from foods and excessive loss from bleeding than by its paucity in the diet. Iron-deficiency anemia in early life can produce negative cognitive and developmental repercussions lasting through adolescence. Adverse consequences can result from the exposure of the intestines to oral iron therapy...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494899
EISBN: 978-3-318-06471-1
... Abstract In utero androgen excess reliably induces polycystic ovary syndrome (PCOS)-like reproductive and metabolic traits in female monkeys, sheep, rats, and mice. In humans, however, substantial technical and ethical constraints on fetal sampling have curtailed safe, pathogenic exploration...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494902
EISBN: 978-3-318-06471-1
... by their circulating serum levels, within a narrow window, outside of which disturbances in metabolism are observed. Thus, androgen excess in women, as documented in those with polycystic ovary syndrome, can adversely affect insulin sensitivity, promoting visceral adiposity, adipose tissue dysfunction, and, ultimately...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494907
EISBN: 978-3-318-06471-1
... Abstract Unwanted sexual hair growth has a considerable negative impact on a woman’s self-esteem and quality of life. Excessive growth of terminal hair in women in a man-like pattern is defined as hirsutism and affects up to 1 in 7 women. Androgens secreted by the ovary and adrenal are the main...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494910
EISBN: 978-3-318-06471-1
... with androgen excess experience polycystic ovary syndrome (PCOS), whereas the prevalence of idiopathic hirsutism and idiopathic hyperandrogenemia is about 5–20, 2–4%, for nonclassic congenital adrenal hyperplasia and 0.2% for androgen-secreting neoplasms [ 1 - 3 ]. Cushing’s syndrome, acromegaly...
Book
Book Cover Image
Series: Frontiers of Hormone Research
Volume: 46
Published: 23 May 2016
10.1159/isbn.978-3-318-05840-6
EISBN: 978-3-318-05840-6
Book Chapter
Series: Frontiers of Hormone Research
Volume: 46
Published: 23 May 2016
10.1159/000443864
EISBN: 978-3-318-05840-6
... Abstract Cushing's syndrome (CS) is a severe chronic and systemic condition caused by endogenous or exogenous excess of glucocorticoids, associated with increased morbidity and mortality. Patients with active CS suffer from many metabolic alterations, including visceral obesity, systemic...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 46
Published: 23 May 2016
10.1159/000443868
EISBN: 978-3-318-05840-6
... hypercortisolism, is associated with deficits in concentration and memory, as well as a wide range of cognitive impairments; therefore, it is a good human model to evaluate the effects of cortisol excess on the brain. Structural and Functional Alterations Hippocampus The hippocampus, a subcortical brain...
Book Chapter
Series: Frontiers in Diabetes
Volume: 22
Published: 10 April 2014
10.1159/000357242
EISBN: 978-3-318-02598-9
... Abstract This chapter tries to address the fascinating interplay between the glucose-insulin system and the growth hormone (GH)-insulin-like growth factor 1 system from the angle of GH excess. As these two systems are so closely linked, one might expect that when GH secretion is pathologically...
Book Chapter
Series: Frontiers in Diabetes
Volume: 22
Published: 10 April 2014
10.1159/000357244
EISBN: 978-3-318-02598-9
... Abstract Glucocorticoid excess may have adverse effects on glucose tolerance by various mechanisms. They may not only induce defective pancreatic insulin secretion, but also increase insulin resistance and food intake while translocating glucose transporters from the plasma membrane. About 20...
Book Chapter
Series: Frontiers in Diabetes
Volume: 22
Published: 10 April 2014
10.1159/000357245
EISBN: 978-3-318-02598-9
... of Catecholamine Excess If catecholamine excess denotes a pathological increase in catecholamine plasma levels, only patients affected by a chromaffin tumor (an adrenal pheochromocytoma or an extraadrenal paraganglioma) may be taken into account. In these patients, depending on the site and genetic background...
Book Chapter
Book Chapter
Series: Endocrine Development
Volume: 13
Published: 05 June 2008
10.1159/000134831
EISBN: 978-3-8055-8581-1
... Abstract Adrenal androgen excess is found in adult female rhesus monkeys previously exposed to androgen treatmentduring early gestation. In adulthood, such prenatally androgenized female monkeys exhibit elevatedbasal circulating levels of dehydroepiandrosterone sulfate (DHEAS), typical...
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Book Chapter
Series: Advances in Psychosomatic Medicine
Volume: 19
Published: 21 September 1989
10.1159/000417398
EISBN: 978-3-318-03173-7
Book Chapter
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